Tylosis may refer to:
;In medicine:
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Diffuse nonepidermolytic palmoplantar keratoderma, a skin condition of the palms and soles
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Howel–Evans syndrome, a skin condition of the palms and soles that is also associated with esophageal cancer
;Other uses:
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Tylosis (botany)
In woody plants, a tylosis (plural: tyloses) is a bladder-like distension of a parenchyma cell into the lumen of adjacent vessels. The term tylosis summarises the physiological process and the resulting occlusion in the xylem of woody plants as re ...
, a process in tree decay
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Tylosis (beetle), a genus of longhorn beetle
{{disambiguation
Palmoplantar keratodermas