Twilight anesthesia is an
anesthetic technique where a mild dose of sedation is applied to induce
anxiolysis (anxiety relief),
hypnosis, and
anterograde amnesia (inability to form new memories). The patient is not unconscious, but sedated. During surgery or other medical procedures, the patient is under what is known as a "twilight state", where the patient is relaxed and "sleepy", able to follow simple directions by the doctor, and is responsive.
Generally, twilight anesthesia causes the patient to forget the surgery and the time right after. It is used for a variety of surgical procedures and for various reasons. Like regular
anesthesia
Anesthesia (American English) or anaesthesia (British English) is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes. It may include some or all of analgesia (relief from or prev ...
, twilight anesthesia is designed to help a patient feel more comfortable and to minimize pain associated with the procedure being performed and to allow the medical practitioner to practice without interruptions.
Overview
Twilight anesthesia is also known as twilight sleep and allows an easy awakening and a speedy recovery time for the patient.
Anesthesia
Anesthesia (American English) or anaesthesia (British English) is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes. It may include some or all of analgesia (relief from or prev ...
is used to control pain by using medicines that reversibly block nerve conduction near the site of administration, therefore, generating a loss of sensation at the area administered. Close monitoring by the anesthesia provider will sometimes be provided, to help keep the patient comfortable during a medical procedure, along with other drugs to help relax the body. It can also help control breathing,
blood pressure
Blood pressure (BP) is the pressure of Circulatory system, circulating blood against the walls of blood vessels. Most of this pressure results from the heart pumping blood through the circulatory system. When used without qualification, the term ...
,
blood flow
Hemodynamics American and British English spelling differences#ae and oe, or haemodynamics are the Fluid dynamics, dynamics of blood flow. The circulatory system is controlled by homeostasis, homeostatic mechanisms of autoregulation, just as hydrau ...
, and
heart rate and rhythm, when needed.
There are four levels of sedation by anesthesia.
Level one
This level, called ''minimal sedation'', causes
anxiolysis, a drug-induced state in which the patient responds normally to verbal commands. Although the
cognition
Cognition is the "mental action or process of acquiring knowledge and understanding through thought, experience, and the senses". It encompasses all aspects of intellectual functions and processes such as: perception, attention, thought, ...
and coordination of the patient are impaired,
cardiovascular
In vertebrates, the circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the body. It includes the cardiovascular system, or vascular system, that consists of the heart a ...
and ventilatory functions remain unaffected.
Level two
This level, called ''moderate sedation/analgesia'' or ''conscious sedation'', causes a drug induced
depression of consciousness during which the patient responds purposefully to verbal commands, either alone or accompanied with light physical stimulation.
Breathing tubes are not required for this type of
anesthesia
Anesthesia (American English) or anaesthesia (British English) is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes. It may include some or all of analgesia (relief from or prev ...
. This is twilight anesthesia.
Level three
This level, called ''deep sedation/analgesia'', causes a drug-induced depression of consciousness during which the patient cannot be easily aroused, but responds purposefully following repeated or painful stimulation. Ventilatory functions may be impaired, so breathing tubes are required.
Cardiovascular
In vertebrates, the circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the body. It includes the cardiovascular system, or vascular system, that consists of the heart a ...
functions are usually sustained.
Level four
This level, called ''
general anesthesia
General anaesthesia (UK) or general anesthesia (US) is medically induced loss of consciousness that renders a patient unarousable even by painful stimuli. It is achieved through medications, which can be injected or inhaled, often with an analgesi ...
'', causes a drug-induced depression of consciousness during which the patient cannot be aroused even by painful stimulation. Ventilatory function is often impaired and
cardiovascular
In vertebrates, the circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the body. It includes the cardiovascular system, or vascular system, that consists of the heart a ...
functions may be impaired.
Applications
Several factors are taken into consideration when determining which level of
anesthesia
Anesthesia (American English) or anaesthesia (British English) is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes. It may include some or all of analgesia (relief from or prev ...
is used under which type of medical procedures. Along with the factors determined, different types of anesthesia medications are used depending on the medical procedure being done. While the patient is under conscious sedation by anesthesia, depending on the type and dose administered, they are in a state that is called by some, a "twilight" state.
Drugs and technology used
Some of the same drugs used in general anesthesia are also used for twilight anesthesia, except in smaller doses and in a bolus interval (a concentrated mass of a substance administered intravenously for diagnostic or therapeutic purposes). These drugs can be administered via gases, such as
nitrous oxide
Nitrous oxide (dinitrogen oxide or dinitrogen monoxide), commonly known as laughing gas, nitrous, or factitious air, among others, is a chemical compound, an Nitrogen oxide, oxide of nitrogen with the Chemical formula, formula . At room te ...
(laughing gas), or
intravenously, with drugs such as
ketamine
Ketamine is a cyclohexanone-derived general anesthetic and NMDA receptor antagonist with analgesic and hallucinogenic properties, used medically for anesthesia, depression, and pain management. Ketamine exists as its S- (esketamine) a ...
(pediatrics primarily, and infrequently in adults),
propofol, and
midazolam
Midazolam, sold under the brand name Versed among others, is a benzodiazepine medication used for anesthesia, premedication before surgical anesthesia, and procedural sedation, and to treat psychomotor agitation, severe agitation. It induces ...
.
Twilight anesthesia alone is not used to provide relief from surgical pain; therefore, it is always given in conjunction with a local or regional anesthetic. Additionally, IV sedation is frequently administered as a concoction of several agents including those previously mentioned for induction and maintenance of anesthesia, as well as a
benzodiazepine
Benzodiazepines (BZD, BDZ, BZs), colloquially known as "benzos", are a class of central nervous system (CNS) depressant, depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. They are prescribed t ...
(usually midazolam, but
temazepam or
flunitrazepam are also used via the oral route
) and a narcotic/systemic analgesic such as
demerol or
fentanyl
Fentanyl is a highly potent synthetic piperidine opioid primarily used as an analgesic (pain medication). It is 30 to 50 times more Potency (pharmacology), potent than heroin and 50 to 100 times more potent than morphine. Its primary Medici ...
. As discussed in the levels of sedation by anesthesia, assistance with breathing tubes (
ETT or
LMA) are not generally used for this type of anesthesia.
Effects
A few studies have been geared towards studying the effects of post operative
analgesic regimes which measure the quality of recovery period and health-related quality of life. Factors other than degree of analgesia and presence of analgesic agent-related side effects (e.g., fatigue, physical functioning, and mental health) may potentially influence these outcomes.
Twilight anesthesia offers a limited recovery period after procedures, and is usually associated with less nausea and vomiting than
general anesthesia
General anaesthesia (UK) or general anesthesia (US) is medically induced loss of consciousness that renders a patient unarousable even by painful stimuli. It is achieved through medications, which can be injected or inhaled, often with an analgesi ...
which makes it a popular choice among doctors who are performing procedures such as minor plastic surgeries.
Uses
Twilight anesthesia is applied to various types of medical procedures and surgeries. It is a popular choice among surgeons and doctors who are performing anything from minor plastic surgeries to dental work, and procedures that do not require extensive operations or long durations in favor of less nausea and a limited recovery period after surgery.
References
{{DEFAULTSORT:Twilight Anesthesia
Anesthesia
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