''Tupavirus'' is a genus of
viruses
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Viruses are found in almo ...
in the family ''
Rhabdoviridae
''Rhabdoviridae'' is a family of negative-strand RNA viruses in the order ''Mononegavirales''. Vertebrates (including mammals and humans), invertebrates, plants, fungi and protozoans serve as natural hosts. Diseases associated with member virus ...
'', order ''
Mononegavirales
''Mononegavirales'' is an order of negative-strand RNA viruses which have nonsegmented genomes. Some members that cause human disease in this order include Ebola virus, human respiratory syncytial virus, measles virus, mumps virus, Nipah viru ...
''.
Taxonomy
The genus contains the following species:
* ''Tupavirus durham''
* ''Tupavirus incomtus''
* ''Tupavirus klamath''
* ''Tupavirus laniger''
* ''Tupavirus pearsonii''
* ''Tupavirus stheno''
* ''Tupavirus stoliczkanus''
* ''Tupavirus tupaia''
* ''Tupavirus wufeng''
Structure
Tupavirions enveloped, with bullet shaped geometries. These particles are about 160 nm long. Tupavirus genomes are linear, around 11.2 kb in length. The genome codes for 7 proteins.
[
]
Life cycle
Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the viral G glycoproteins to host receptors, which mediates clathrin-mediated endocytosis. Replication follows the negative stranded RNA virus replication model. Negative stranded RNA virus transcription, using polymerase stuttering is the method of transcription. The virus exits the host cell by budding, and tubule-guided viral movement. Birds serve as the natural host for Durham tupavirus,[ with antibodies having been found in the ]American coot
The American coot (''Fulica americana''), also known as a mud hen or pouldeau, is a bird of the family Rallidae. Though commonly mistaken for ducks, American coots are only distantly related to ducks, belonging to a separate order. Unlike the we ...
(''Fulica americana'').[ as well as voles and shrews.][
]
References
External links
Viralzone: Tupavirus
ICTV
{{Taxonbar, from=Q18814196
Rhabdoviridae
Virus genera