In the

skeleton A skeleton is the structural frame that supports the body of an animal. There are several types of skeletons, including the exoskeleton, which is the stable outer shell of an organism, the endoskeleton, which forms the support structure inside ...

of humans and other animals, a tubercle, tuberosity or apophysis is a protrusion or eminence that serves as an attachment for

skeletal muscle Skeletal muscles (commonly referred to as muscles) are organs of the vertebrate muscular system and typically are attached by tendons to bones of a skeleton. The muscle cells of skeletal muscles are much longer than in the other types of m ...

s. The muscles attach by

tendon A tendon or sinew is a tough, high-tensile-strength band of dense fibrous connective tissue that connects muscle to bone. It is able to transmit the mechanical forces of muscle contraction to the skeletal system without sacrificing its ability ...

s, where the

enthesis The enthesis (plural entheses) is the connective tissue between tendon or ligament and bone. There are two types of entheses: ''Fibrous entheses'' and ''fibrocartilaginous entheses''. In a fibrous enthesis, the collagenous tendon or ligament dir ...

is the connective tissue between the tendon and

bone A bone is a rigid organ that constitutes part of the skeleton in most vertebrate animals. Bones protect the various other organs of the body, produce red and white blood cells, store minerals, provide structure and support for the body, an ...

. A ''tuberosity'' is generally a larger tubercle.

Main tubercles

Humerus

The

humerus The humerus (; ) is a long bone in the arm that runs from the shoulder to the elbow. It connects the scapula and the two bones of the lower arm, the radius and ulna, and consists of three sections. The humeral upper extremity consists of a roun ...

has two tubercles, the

greater tubercle The greater tubercle of the humerus is the outward part the upper end of that bone, adjacent to the large rounded prominence of the humerus head. It provides attachment points for the supraspinatus, infraspinatus, and teres minor muscles, thre ...

and the

lesser tubercle The lesser tubercle of the humerus, although smaller, is more prominent than the greater tubercle: it is situated in front, and is directed medially and anteriorly. The projection of the lesser tubercle is anterior from the junction that is found ...

. These are situated at the

proximal Standard anatomical terms of location are used to unambiguously describe the anatomy of animals, including humans. The terms, typically derived from Latin or Greek roots, describe something in its standard anatomical position. This position ...

end of the bone, that is the end that connects with the

scapula The scapula (plural scapulae or scapulas), also known as the shoulder blade, is the bone that connects the humerus (upper arm bone) with the clavicle (collar bone). Like their connected bones, the scapulae are paired, with each scapula on eithe ...

. The greater/lesser tubercule is located from the top of the

acromion In human anatomy, the acromion (from Greek: ''akros'', "highest", ''ōmos'', "shoulder", plural: acromia) is a bony process on the scapula (shoulder blade). Together with the coracoid process it extends laterally over the shoulder joint. The ac ...

laterally and inferiorly. The radius has two, the

radial tuberosity Beneath the neck of the radius, on the medial side, is an eminence, the radial tuberosity; its surface is divided into: * a ''posterior, rough portion'', for the insertion of the tendon of the biceps brachii. * an ''anterior, smooth portion'', on ...

and Lister's tubercle.

Ribs

On a

rib In vertebrate anatomy, ribs ( la, costae) are the long curved bones which form the rib cage, part of the axial skeleton. In most tetrapods, ribs surround the chest, enabling the lungs to expand and thus facilitate breathing by expanding the ch ...

, tubercle is an eminence on the back surface, at the junction between the neck and the body of the rib. It consists of an articular and a non-articular area. The lower and more medial articular area is a small oval surface for articulation with the transverse process of the lower of the two vertebrae which gives attachment to the head. The higher, non-articular area is a rough elevation which gives attachment to the ligament of the tubercle. The tubercle is much more prominent in the upper ribs than in the lower ribs.

Tibia

The most prominent tubercle of the

tibia The tibia (; ), also known as the shinbone or shankbone, is the larger, stronger, and anterior (frontal) of the two bones in the leg below the knee in vertebrates (the other being the fibula, behind and to the outside of the tibia); it connects ...

, a leg bone which is more commonly known as the shinbone or shankbone, is the

tibial tuberosity The tuberosity of the tibia or tibial tuberosity or tibial tubercle is an elevation on the proximal, anterior aspect of the tibia, just below where the anterior surfaces of the lateral and medial tibial condyles end. Structure The tuberosity o ...

. The tibial tuberosity is located on the tibia's

anterior Standard anatomical terms of location are used to unambiguously describe the anatomy of animals, including humans. The terms, typically derived from Latin or Greek roots, describe something in its standard anatomical position. This position prov ...

surface,

distal Standard anatomical terms of location are used to unambiguously describe the anatomy of animals, including humans. The terms, typically derived from Latin or Greek roots, describe something in its standard anatomical position. This position prov ...

to the medial condyle. It creates a bony prominence just below the

patella The patella, also known as the kneecap, is a flat, rounded triangular bone which articulates with the femur (thigh bone) and covers and protects the anterior articular surface of the knee joint. The patella is found in many tetrapods, such as m ...

, and can be easily located with the fingers. It creates an attachment point for the

ligamentum patellae The patellar tendon is the distal portion of the common tendon of the quadriceps femoris, which is continued from the patella to the tibial tuberosity. It is also sometimes called the patellar ligament as it forms a bone to bone connection when t ...

, or patellar ligament. Other tubercles of the tibia include the

medial intercondylar tubercle The intercondylar area is the separation between the medial and lateral condyle on the upper extremity of the tibia. The anterior and posterior cruciate ligaments and the menisci attach to the intercondylar area. The intercondyloid eminence is ...

, the

lateral intercondylar tubercle The intercondylar area is the separation between the medial and lateral condyle on the upper extremity of the tibia. The anterior and posterior cruciate ligaments and the menisci attach to the intercondylar area. The intercondyloid eminence is ...

, and

Gerdy's tubercle Gerdy's tubercle is a lateral tubercle of the tibia, located where the iliotibial tract inserts. It was named after French surgeon Pierre Nicolas Gerdy (1797–1856). Gerdy's tubercle is a smooth facet on the lateral aspect of the upper part of t ...

Femur

A ''trochanter'' is one of up to three tubercles of the

femur The femur (; ), or thigh bone, is the proximal bone of the hindlimb in tetrapod vertebrates. The head of the femur articulates with the acetabulum in the pelvic bone forming the hip joint, while the distal part of the femur articulates wit ...

: *

Greater trochanter The greater trochanter of the femur is a large, irregular, quadrilateral eminence and a part of the skeletal system. It is directed lateral and medially and slightly posterior. In the adult it is about 2–4 cm lower than the femoral head.Stan ...

Lesser trochanter The lesser trochanter is a conical posteromedial bony projection of the femoral shaft. it serves as the principal insertion site of the iliopsoas muscle. Structure The lesser trochanter is a conical posteromedial projection of the shaft of the f ...

Third trochanter In human anatomy, the third trochanter is a bony projection occasionally present on the proximal femur near the superior border of the gluteal tuberosity. When present, it is oblong, rounded, or conical in shape and sometimes continuous with the g ...

, which is occasionally present

Fifth metatarsal

$Proximal fractures of 5th metatarsal$ In the

fifth metatarsal The fifth metatarsal bone is a long bone in the foot, and is palpable along the distal outer edges of the feet. It is the second smallest of the five metatarsal bones. The fifth metatarsal is analogous to the fifth metacarpal bone in the hand. As ...

bone, the most proximal part of the bone is termed the "tuberosity", and the secondary

ossification center An ossification center is a point where ossification of the cartilage begins. The first step in ossification is that the cartilage cells at this point enlarge and arrange themselves in rows.Gray and Spitzka (1910), page 44. The matrix in which t ...

that is normally present thereon in children is termed the "apophysis".

Related diseases and conditions

Fractures

The main type of fracture affecting tubercles is

avulsion fracture An avulsion fracture is a bone fracture which occurs when a fragment of bone tears away from the main mass of bone as a result of physical trauma. This can occur at the ligament by the application of forces external to the body (such as a fal ...

, by pulling the attached tendon.

Apophysitis

''Apophysitis'' is an

inflammation Inflammation (from la, wikt:en:inflammatio#Latin, inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or Irritation, irritants, and is a protective response involving im ...

of a tubercle. It mainly affects growing children, with overuse of the affected tubercle. Examples include: *

Osgood–Schlatter disease Osgood–Schlatter disease (OSD) is inflammation of the patellar ligament at the tibial tuberosity (apophysitis). It is characterized by a painful bump just below the knee that is worse with activity and better with rest. Episodes of pain typica ...

(apophysitis of the tibial tubercle) * Sever's disease (apophysitis of the posterior tubercle of the heel) * Sinding-Larsen and Johansson syndrome (apophysitis of the inferior pole of the

)

Enthesitis

Enthesitis Enthesitis is inflammation of the entheses, the sites where tendons or ligaments insert into the bone. It is an enthesopathy, a pathologic condition of the entheses. Early clinical manifestations are an aching sensation akin to "working out too ...

'' is an anatomically close but separate condition, wherein there is inflammation of the

entheses The enthesis (plural entheses) is the connective tissue between tendon or ligament and bone. There are two types of entheses: ''Fibrous entheses'' and ''fibrocartilaginous entheses''. In a fibrous enthesis, the collagenous tendon or ligament dir ...

, the sites where tendons or ligaments insert into the bone. It is associated with

HLA B27 Human leukocyte antigen (HLA) B27 (subtypes B*2701-2759) is a class I surface antigen encoded by the B locus in the major histocompatibility complex (MHC) on chromosome 6 and presents antigenic peptides (derived from self and non-self antigens) to ...

arthropathies such as

ankylosing spondylitis Ankylosing spondylitis (AS) is a type of arthritis characterized by long-term inflammation of the joints of the spine typically where the spine joins the pelvis. Occasionally areas affected may include other joints such as the shoulders or hi ...

psoriatic arthritis Psoriatic arthritis is a long-term inflammatory arthritis that occurs in people affected by the autoimmune disease psoriasis. The classic feature of psoriatic arthritis is swelling of entire fingers and toes with a sausage-like appearance. ...

, and

reactive arthritis Reactive arthritis, also known as Reiter's syndrome, is a form of inflammatory arthritis that develops in response to an infection in another part of the body (cross-reactivity). Coming into contact with bacteria and developing an infection can ...

References

{{reflist Skeletal system