Troxerutin is a

flavonol Flavonols are a class of flavonoids that have the 3-hydroxyflavone backbone (IUPAC name: 3-hydroxy-2-phenylchromen-4-one). Their diversity stems from the different positions of the phenolic –OH groups. They are distinct from flavanols (with ...

, a type of flavonoid, derived from

rutin Rutin (rutoside, quercetin-3-O-rutinoside or sophorin) is the glycoside combining the flavonol quercetin and the disaccharide rutinose (α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranose). It is a flavonoid glycoside found in a wide variety of pla ...

. It is more accurately a

hydroxyethylrutoside Hydroxyethylrutosides (oxerutins, ''O''-beta-hydroxyethyl-rutosides, HR, or HER) are hydroxyethyl derivatives of rutosides. Examples include: * Monoxerutin * Dihydroxyethylrutoside * Troxerutin * Tetrahydroxyethylrutoside Oxerutins are semis ...

. It can be isolated from '' Sophora japonica'', the Japanese pagoda tree. It is used as a vasoprotective. Troxerutin has been shown in mice to reverse CNS insulin resistance and reduce

reactive oxygen species In chemistry and biology, reactive oxygen species (ROS) are highly Reactivity (chemistry), reactive chemicals formed from diatomic oxygen (), water, and hydrogen peroxide. Some prominent ROS are hydroperoxide (H2O2), superoxide (O2−), hydroxyl ...

induced by a high-cholesterol diet.

References

Quercetin glycosides Flavonol rutinosides Phenol ethers {{cardiovascular-drug-stub