The Trost ligand is a

diphosphine Diphosphane, or diphosphine, is an inorganic compound with the chemical formula . This colourless liquid is one of several binary phosphorus hydrides. It is the impurity that typically causes samples of phosphine to ignite in air. Properties, ...

used in the

palladium Palladium is a chemical element; it has symbol Pd and atomic number 46. It is a rare and lustrous silvery-white metal discovered in 1802 by the English chemist William Hyde Wollaston. He named it after the asteroid Pallas (formally 2 Pallas), ...

- catalyzed Trost asymmetric allylic alkylation. Other C₂-symmetric ligands derived from ''trans''-1,2-diaminocyclohexane (DACH) have been developed, such as the (''R'',''R'')-DACH- naphthyl ligand derived from 2-diphenylphosphino-1-naphthalenecarboxylic acid. Related bidentate

phosphine Phosphine (IUPAC name: phosphane) is a colorless, flammable, highly toxic compound with the chemical formula , classed as a pnictogen hydride. Pure phosphine is odorless, but technical grade samples have a highly unpleasant odor like rotting ...

-containing ligands derived from other chiral

diamines A diamine is an amine with two amino groups. Diamines are used as monomers to prepare polyamides, polyimides, and polyureas. The term ''diamine'' refers mostly to Primary (chemistry), primary diamines, as those are the most reactive. In terms of ...

and 2-diphenylphosphinobenzoic acid have also been developed for applications in asymmetric synthesis.

External links

Sigma-Aldrich: Trost Ligands

Trost Research Group
Reagents for organic chemistry Catalysts Tertiary phosphines Benzamides {{Catalysis-stub