Trofosfamide (
INN) is a
nitrogen mustard
Nitrogen mustards are cytotoxic organic compounds with the chloroethylamine (Cl(CH2)2NR2) functional group. Although originally produced as chemical warfare agents, they were the first chemotherapeutic agents for treatment of cancer. Nitrogen m ...
alkylating agent. It is sometimes abbreviated "TRO".
It has been used in trials to study its effects on
ependymoma,
medulloblastoma,
sarcoma, soft tissue,
supratentorial PNET, and recurrent brain tumors.
References
Organochlorides
Oxazaphosphinans
Phosphorodiamidates
Nitrogen mustards
Chloroethyl compounds
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