Triethylenemelamine (abbreviated TEM, also called Tretamine) is a drug used in
chemotherapy
Chemotherapy (often abbreviated chemo, sometimes CTX and CTx) is the type of cancer treatment that uses one or more anti-cancer drugs (list of chemotherapeutic agents, chemotherapeutic agents or alkylating agents) in a standard chemotherapy re ...
.
It can cause
chromatid
A chromatid (Greek ''khrÅmat-'' 'color' + ''-id'') is one half of a duplicated chromosome. Before replication, one chromosome is composed of one DNA molecule. In replication, the DNA molecule is copied, and the two molecules are known as chrom ...
aberrations in cell models.
See also
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Altretamine
Altretamine (trade name Hexalen), also called hexamethylmelamine, is an antineoplastic agent. It was approved by the U.S. FDA in 1990.
Uses
It is indicated for use as a single agent in the palliative treatment of patients with persistent or r ...
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thiotepa
Thiotepa (N,N',N''(-triethylenethiophosphoramide, INN), sold under the brand name Tepadina among others, is an anti-cancer medication.
Thiotepa is an organophosphorus compound with the formula (C2H4N)3PS.
History
Thiotepa and its synthesis ...
References
Alkylating antineoplastic agents
Triazines
1-Aziridinyl compounds
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