Tricetin 3',4',5'-O-trimethyltransferase (, ''FOMT'', ''TaOMT1'', ''TaCOMT1'', ''TaOMT2'') is an

enzyme An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...

with

systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivi ...

''S-adenosyl-L-methionine:tricetin 3',4',5'-O-trimethyltransferase''. This enzyme catalyses the following

chemical reaction A chemical reaction is a process that leads to the chemistry, chemical transformation of one set of chemical substances to another. When chemical reactions occur, the atoms are rearranged and the reaction is accompanied by an Gibbs free energy, ...

: 3

S-adenosyl-L-methionine ''S''-Adenosyl methionine (SAM), also known under the commercial names of SAMe, SAM-e, or AdoMet, is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation. Although these anabolic reactions occur throug ...

+ tricetin

\rightleftharpoons

3 S-adenosyl-L-homocysteine + 3',4',5'-O-trimethyltricetin (overall reaction) :(1a) S-adenosyl-L-methionine + tricetin

\rightleftharpoons

S-adenosyl-L-homocysteine + 3'-O-methyltricetin :(1b) S-adenosyl-L-methionine + 3'-O-methyltricetin

\rightleftharpoons

S-adenosyl-L-homocysteine + 3',5'-O-dimethyltricetin :(1c) S-adenosyl-L-methionine + 3',5'-O-dimethyltricetin

\rightleftharpoons

S-adenosyl-L-homocysteine + 3',4',5'-O-trimethyltricetin The enzyme from ''

Triticum aestivum Common wheat (''Triticum aestivum''), also known as bread wheat, is a cultivated wheat species. About 95% of wheat produced worldwide is common wheat; it is the most widely grown of all crops and the cereal with the highest monetary yield. Ta ...

'' catalyses the sequential O-methylation of tricetin via 3'-O-methyltricetin, 3',5'-O-methyltricetin to 3',4',5'-O-trimethyltricetin.

References

External links

* {{Portal bar, Biology, border=no EC 2.1.1 O-methylated flavones metabolism