Transient neonatal diabetes mellitus (TNDM) is a form of
neonatal diabetes Neonatal diabetes mellitus (NDM) is a disease that affects an infant and their body's ability to produce or use insulin. NDM is a kind of diabetes that is monogenic (regulated by a single gene) and arises in the first 6 months of life. Infants do ...
presenting at birth that is not permanent. This disease is considered to be a type of
maturity onset diabetes of the young
Maturity or immaturity may refer to:
* Adulthood or age of majority
* Maturity model
** Capability Maturity Model, in software engineering, a model representing the degree of formality and optimization of processes in an organization
* Developme ...
(MODY).
Types
Cause
This condition has to do with genetics and is often associated with having an added Chromosome 7 gene (mostly from the paternal side).
The form on chromosome 6 can involve
imprinting.
Diagnosis
Management
See also
*
Permanent neonatal diabetes mellitus
Permanent neonatal diabetes mellitus (PNDM) is a newly identified and potentially treatable form of monogenic diabetes. This type of neonatal diabetes is caused by activating mutations of the '' KCNJ11'' gene, which codes for the Kir6.2 subunit of ...
References
Further reading
GeneReview/NIH/UW entry on 6q24-Related Transient Neonatal Diabetes Mellitush1>
External links
{{DEFAULTSORT:Transient Neonatal Diabetes Mellitus
Types of diabetes
Neonatology