
In
physiology
Physiology (; ) is the science, scientific study of function (biology), functions and mechanism (biology), mechanisms in a life, living system. As a branches of science, subdiscipline of biology, physiology focuses on how organisms, organ syst ...
, transduction is the translation of arriving stimulus into an action potential by a sensory receptor. It begins when stimulus changes the membrane potential of a
sensory receptor
Sensory neurons, also known as afferent neurons, are neurons in the nervous system, that convert a specific type of stimulus, via their receptors, into action potentials or graded receptor potentials. This process is called sensory transduc ...
.
A sensory receptor converts the energy in a stimulus into an electrical signal.
Receptors are broadly split into two main categories: exteroceptors, which receive external sensory stimuli, and interoceptors, which receive internal sensory stimuli.
Sensory transduction
The visual system
In the
visual system
The visual system is the physiological basis of visual perception (the ability to perception, detect and process light). The system detects, phototransduction, transduces and interprets information concerning light within the visible range to ...
, sensory cells called
rod and
cone cell
Cone cells or cones are photoreceptor cells in the retina of the vertebrate eye. Cones are active in daylight conditions and enable photopic vision, as opposed to rod cells, which are active in dim light and enable scotopic vision. Most v ...
s in the
retina
The retina (; or retinas) is the innermost, photosensitivity, light-sensitive layer of tissue (biology), tissue of the eye of most vertebrates and some Mollusca, molluscs. The optics of the eye create a focus (optics), focused two-dimensional ...
convert the physical energy of
light
Light, visible light, or visible radiation is electromagnetic radiation that can be visual perception, perceived by the human eye. Visible light spans the visible spectrum and is usually defined as having wavelengths in the range of 400– ...
signals into
electrical impulses that travel to the
brain
The brain is an organ (biology), organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It consists of nervous tissue and is typically located in the head (cephalization), usually near organs for ...
. The light causes a conformational change in a protein called
rhodopsin
Rhodopsin, also known as visual purple, is a protein encoded by the ''RHO'' gene and a G-protein-coupled receptor (GPCR). It is a light-sensitive receptor protein that triggers visual phototransduction in rod cells. Rhodopsin mediates dim ...
.
This conformational change sets in motion a series of molecular events that result in a reduction of the electrochemical gradient of the photoreceptor.
The decrease in the electrochemical gradient causes a reduction in the electrical signals going to the brain. Thus, in this example, more light hitting the photoreceptor results in the transduction of a signal into fewer electrical impulses, effectively communicating that stimulus to the brain. A change in neurotransmitter release is mediated through a second messenger system. The change in neurotransmitter release is by rods. Because of the change, a change in light intensity causes the response of the rods to be much slower than expected (for a process associated with the nervous system).
[Silverthorn, Dee Unglaub. Human Physiology: An Integrated Approach, 3rd Edition, Inc, San Francisco, CA, 2004.]
The auditory system
In the
auditory system
The auditory system is the sensory system for the sense of hearing. It includes both the ear, sensory organs (the ears) and the auditory parts of the sensory system.
System overview
The outer ear funnels sound vibrations to the eardrum, incre ...
, sound vibrations (mechanical energy) are transduced into electrical energy by hair cells in the inner ear. Sound vibrations from an object cause vibrations in air molecules, which in turn, vibrate the
ear drum
In the anatomy of humans and various other tetrapods, the eardrum, also called the tympanic membrane or myringa, is a thin, cone-shaped membrane that separates the external ear from the middle ear. Its function is to transmit changes in pressur ...
. The movement of the eardrum causes the bones of the middle ear (the
ossicles
The ossicles (also called auditory ossicles) are three irregular bones in the middle ear of humans and other mammals, and are among the smallest bones in the human body. Although the term "ossicle" literally means "tiny bone" (from Latin ''ossi ...
) to vibrate. These vibrations then pass into the
cochlea
The cochlea is the part of the inner ear involved in hearing. It is a spiral-shaped cavity in the bony labyrinth, in humans making 2.75 turns around its axis, the modiolus (cochlea), modiolus. A core component of the cochlea is the organ of Cort ...
, the organ of hearing. Within the cochlea, the hair cells on the sensory epithelium of the
organ of Corti bend and cause movement of the basilar membrane. The membrane undulates in different sized waves according to the frequency of the sound. Hair cells are then able to convert this movement (mechanical energy) into electrical signals (graded receptor potentials) which travel along auditory nerves to hearing centres in the brain.
The olfactory system
In the
olfactory system
The olfactory system, is the sensory nervous system, sensory system used for the sense of smell (olfaction). Olfaction is one of the special senses directly associated with specific organs. Most mammals and reptiles have a main olfactory system ...
, odorant molecules in the mucus bind to G-protein receptors on olfactory cells. The G-protein activates a downstream signalling cascade that causes increased level of cyclic-AMP (cAMP), which trigger neurotransmitter release.
The gustatory system
In the
gustatory system
The gustatory system or sense of taste is the sensory system that is partially responsible for the perception of taste. Taste is the perception stimulated when a substance in the mouth reacts chemically with taste receptor cells located on t ...
, perception of five primary
taste qualities (sweet, salty, sour, bitter and umami
avoriness) depends on taste transduction pathways, through taste receptor cells, G proteins, ion channels, and effector enzymes.
The somatosensory system
In the
somatosensory system
The somatosensory system, or somatic sensory system is a subset of the sensory nervous system. The main functions of the somatosensory system are the perception of external stimuli, the perception of internal stimuli, and the regulation of bod ...
the sensory transduction mainly involves the conversion of the mechanical signal such as pressure, skin compression, stretch, vibration to electro-ionic impulses through the process of
mechanotransduction.
It also includes the sensory transduction related to
thermoception
In physiology, thermoception or thermoreception is the sensation and perception of temperature, or more accurately, temperature differences inferred from heat flux. It deals with a series of events and processes required for an organism to recei ...
and
nociception
In physiology, nociception , also nocioception; ) is the Somatosensory system, sensory nervous system's process of encoding Noxious stimulus, noxious stimuli. It deals with a series of events and processes required for an organism to receive a pai ...
.
References
{{DEFAULTSORT:Transduction (Physiology)
Physiology