Trans-Feruloyl—CoA Synthase
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''trans''-Feruloyl—CoA synthase () is an enzyme that catalyzes the
chemical reaction A chemical reaction is a process that leads to the chemistry, chemical transformation of one set of chemical substances to another. When chemical reactions occur, the atoms are rearranged and the reaction is accompanied by an Gibbs free energy, ...
:ferulic acid + CoASH + ATP \rightleftharpoons ''trans''-feruloyl—CoA + products of ATP breakdown The three substrates of this enzyme are
ferulic acid Ferulic acid is a hydroxycinnamic acid derivative and a phenolic compound. It is an organic compound with the formula (CH3O)HOC6H3CH=CHCO2H. The name is derived from the genus '' Ferula'', referring to the giant fennel ('' Ferula communis''). Cl ...
, CoASH, and ATP, whereas its two
products Product may refer to: Business * Product (business), an item that can be offered to a market to satisfy the desire or need of a customer. * Product (project management), a deliverable or set of deliverables that contribute to a business solution ...
are ''trans''-feruloyl—CoA and products of ATP breakdown. This enzyme belongs to the family of
ligase In biochemistry, a ligase is an enzyme that can catalyze the joining ( ligation) of two molecules by forming a new chemical bond. This is typically via hydrolysis of a small pendant chemical group on one of the molecules, typically resulting i ...
s, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivi ...
of this enzyme class is ''trans''-ferulate:CoASH ligase (ATP-hydrolysing). This enzyme is also called ''trans''-feruloyl—CoA synthetase.


References

* * EC 6.2.1 Enzymes of unknown structure {{ligase-stub