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Tracheal collapse in dogs is a condition characterized by incomplete formation or weakening of the
cartilaginous Cartilage is a resilient and smooth type of connective tissue. Semi-transparent and non-porous, it is usually covered by a tough and fibrous membrane called perichondrium. In tetrapods, it covers and protects the ends of long bones at the joints ...
rings of the
trachea The trachea (: tracheae or tracheas), also known as the windpipe, is a cartilaginous tube that connects the larynx to the bronchi of the lungs, allowing the passage of air, and so is present in almost all animals' lungs. The trachea extends from ...
resulting in flattening of the trachea. It can be
congenital A birth defect is an abnormal condition that is present at childbirth, birth, regardless of its cause. Birth defects may result in disability, disabilities that may be physical disability, physical, intellectual disability, intellectual, or dev ...
or acquired, and extrathoracic or intrathoracic (inside or outside the thoracic cavity). Tracheal collapse is a dynamic condition. Collapse of the cervical trachea or extrathoracic (in the neck) occurs during inspiration; collapse of the thoracic trachea or intrathoracic (in the chest) occurs during expiration. Tracheal collapse is most commonly found in small
dog The dog (''Canis familiaris'' or ''Canis lupus familiaris'') is a domesticated descendant of the gray wolf. Also called the domestic dog, it was selectively bred from a population of wolves during the Late Pleistocene by hunter-gatherers. ...
breeds, including the Chihuahua, Pomeranian, Toy Poodle, Shih Tzu, Lhasa Apso,
Maltese Maltese may refer to: * Someone or something of, from, or related to Malta * Maltese alphabet * Maltese cuisine * Maltese culture * Maltese language, the Semitic language spoken by Maltese people * Maltese people, people from Malta or of Maltese ...
,
Pug The Pug is a breed of dog with the physically distinctive features of a wrinkly, short-muzzled face, and curled tail. An ancient breed, with roots dating back to 400 B.C., they have a fine, glossy coat that comes in a variety of colors, most ...
, and
Yorkshire Terrier The Yorkshire Terrier, also known as a Yorkie, is a British breed of toy dog of terrier type. It is among the smallest of the terriers and indeed of all dog breeds, with a weight of no more than . It originated in the nineteenth century in the ...
. Congenital tracheal collapse appears to be caused by a deficiency of normal components of tracheal ring cartilage like
glycosaminoglycan Glycosaminoglycans (GAGs) or mucopolysaccharides are long, linear polysaccharides consisting of repeating disaccharide units (i.e. two-sugar units). The repeating two-sugar unit consists of a uronic sugar and an amino sugar, except in the case o ...
s,
glycoprotein Glycoproteins are proteins which contain oligosaccharide (sugar) chains covalently attached to amino acid side-chains. The carbohydrate is attached to the protein in a cotranslational or posttranslational modification. This process is known a ...
s,
calcium Calcium is a chemical element; it has symbol Ca and atomic number 20. As an alkaline earth metal, calcium is a reactive metal that forms a dark oxide-nitride layer when exposed to air. Its physical and chemical properties are most similar to it ...
, and
chondroitin A chondroitin is a chondrin derivative. Types include: * Chondroitin sulfate * Dermatan sulfate Chondroitin as a supplement is now commonly used (often in combination with glucosamine) in treating the joint disease of osteoarthritis. In contra ...
. Acquired tracheal collapse can be caused by
Cushing's syndrome Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol. Signs and symptoms may include high blood pressure, abdominal obesity but with thin arms and legs, reddish stretch marks, ...
, heart disease, and chronic respiratory disease and infection. Symptoms include a cough (often called a "goose honk cough" due to its sound), especially when the dog is excited. This cough is usually
paroxysm Paroxysmal attacks or paroxysms are a sudden recurrence or intensification of symptoms, such as a spasm or seizure. These short, frequent symptoms can be observed in various clinical conditions. They are usually associated with multiple scleros ...
al in nature. Other symptoms include exercise intolerance, respiratory distress, and gagging while eating or drinking. Tracheal collapse is easily seen on a
radiograph Radiography is an imaging technique using X-rays, gamma rays, or similar ionizing radiation and non-ionizing radiation to view the internal form of an object. Applications of radiography include medical ("diagnostic" radiography and "therapeu ...
as a narrowing of the tracheal lumen. Treatment for mild to moderate cases include
corticosteroid Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are invo ...
s,
bronchodilator A bronchodilator or broncholytic (although the latter occasionally includes secretory inhibition as well) is a substance that dilates the bronchi and bronchioles, decreasing resistance in the respiratory airway and increasing airflow to the lun ...
s, and
antitussive Cold medicines are a group of medications taken individually or in combination as a treatment for the symptoms of the common cold and similar conditions of the upper respiratory tract. The term encompasses a broad array of drugs, including ana ...
s. Medical treatment is successful in about 70 percent of tracheal collapse cases. Severe cases can be treated with surgical implantation of a tracheal
stent In medicine, a stent is a tube usually constructed of a metallic alloy or a polymer. It is inserted into the Lumen (anatomy), lumen (hollow space) of an anatomic vessel or duct to keep the passageway open. Stenting refers to the placement of ...
(inside or outside of the trachea) or prosthetic rings. Extraluminal (outside the trachea) stenting is generally used only for tracheal collapse in the neck region. Intraluminal stenting has shown more promise for success with intrathoracic cases, especially using nitinol, a type of
shape memory alloy In metallurgy, a shape-memory alloy (SMA) is an alloy that can be deformed when cold but returns to its pre-deformed ("remembered") shape when heated. It is also known in other names such as memory metal, memory alloy, smart metal, smart alloy, ...
composed of
nickel Nickel is a chemical element; it has symbol Ni and atomic number 28. It is a silvery-white lustrous metal with a slight golden tinge. Nickel is a hard and ductile transition metal. Pure nickel is chemically reactive, but large pieces are slo ...
and
titanium Titanium is a chemical element; it has symbol Ti and atomic number 22. Found in nature only as an oxide, it can be reduced to produce a lustrous transition metal with a silver color, low density, and high strength, resistant to corrosion in ...
. Potential problems include stent migration and fracture. Tracheal collapse has also been described in
horse The horse (''Equus ferus caballus'') is a domesticated, one-toed, hoofed mammal. It belongs to the taxonomic family Equidae and is one of two extant subspecies of ''Equus ferus''. The horse has evolved over the past 45 to 55 mi ...
s, both as a congenital condition and as a result of trauma. It is most commonly seen in the cervical trachea.


See also

* Laryngeal saccules


References

{{reflist Dog diseases