Toxin (alternative Medicine)
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Detoxification (often shortened to detox and sometimes called body cleansing) is a type of
alternative-medicine Alternative medicine refers to practices that aim to achieve the healing effects of conventional medicine, but that typically lack biological plausibility, testability, repeatability, or supporting evidence of effectiveness. Such practices ar ...
treatment which aims to rid the body of unspecified "toxins" – substances that proponents claim accumulate in the body over time and have undesirable short-term or long-term effects on individual health. It is not to be confused with
detoxification Detoxification or detoxication (detox for short) is the physiological or medicinal removal of toxic substances from a living organism, including the human body, which is mainly carried out by the liver. Additionally, it can refer to the period o ...
carried out by the
liver The liver is a major metabolic organ (anatomy), organ exclusively found in vertebrates, which performs many essential biological Function (biology), functions such as detoxification of the organism, and the Protein biosynthesis, synthesis of var ...
and
kidneys In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organs that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation. They are located on the left and right in the retro ...
, which filter the blood and remove harmful substances to be processed and eliminated from the body. Activities commonly associated with detoxification include
dieting Dieting is the practice of eating food in a regulated way to decrease, maintain, or increase body weight, or to prevent and treat diseases such as diabetes and obesity. As weight loss depends on calorie intake, List of diets, different kinds of ...
,
fasting Fasting is the act of refraining from eating, and sometimes drinking. However, from a purely physiological context, "fasting" may refer to the metabolic status of a person who has not eaten overnight (before "breakfast"), or to the metabolic sta ...
, consuming exclusively or avoiding specific foods (such as fats, carbohydrates, fruits, vegetables, juices, herbs),
colon cleansing Colon cleansing, also known as colon therapy, colon hydrotherapy, a colonic, or colonic irrigation, encompasses a number of alternative medical therapies claimed to remove toxins from the colon and intestinal tract by removing accumulations o ...
,
chelation therapy Chelation therapy is a medical procedure that involves the administration of chelating agents to remove heavy metals from the body. Chelation therapy has a long history of use in clinical toxicology and remains in use for some very specific medic ...
, certain kinds of IV therapy and the removal of dental fillings containing
amalgam Amalgam most commonly refers to: * Amalgam (chemistry), mercury alloy * Amalgam (dentistry), material of silver tooth fillings ** Bonded amalgam, used in dentistry Amalgam may also refer to: * Amalgam Comics, a publisher * Amalgam Digital, an in ...
. Scientists and health organizations have criticized the concept of detoxification for its unsound scientific basis and for the lack of evidence for claims made. The "toxins" usually remain undefined, with little to no evidence of toxic accumulation in the patient. The British organisation
Sense about Science Sense about Science is a United Kingdom charitable organization that promotes the public understanding of science. Sense about Science was founded in 2002 by Lord Taverne, Bridget Ogilvie and others to promote respect for scientific evidence an ...
has described some detox diets and commercial products as "a waste of time and money", while the British Dietetic Association called the idea "nonsense" and a "marketing myth". Dara Mohammadi summarizes "detoxing" as "a scam ..a pseudo-medical concept designed to sell you things", and
Edzard Ernst Edzard Ernst (born 30 January 1948) is a retired British-German academic physician and researcher specializing in the study of complementary and alternative medicine. He was Professor of Complementary Medicine at the University of Exeter, the wo ...
, emeritus professor of complementary medicine, describes it as a term for conventional medical treatments for addiction which has been "hijacked by entrepreneurs, quacks and charlatans to sell a bogus treatment".


Background

Suspicions of the inefficacy of purging became widespread by the 1830s.
Biochemistry Biochemistry, or biological chemistry, is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology, a ...
and
microbiology Microbiology () is the branches of science, scientific study of microorganisms, those being of unicellular organism, unicellular (single-celled), multicellular organism, multicellular (consisting of complex cells), or non-cellular life, acellula ...
appeared to support auto-intoxication theory in the 19th century, but by the early twentieth century detoxification-based approaches quickly fell out of favour.Compare: Even though abandoned by mainstream medicine, the idea has persisted in the popular imagination and amongst
alternative medicine Alternative medicine refers to practices that aim to achieve the healing effects of conventional medicine, but that typically lack biological plausibility, testability, repeatability, or supporting evidence of effectiveness. Such practices are ...
practitioners. Notions of internal cleansing had resurgence along with the rise of alternative medicine in the 1970s and following; it remains unscientific and anachronistic. With the rise of the environmentalist movement, many detox diets use the diet format as a political platform to advocate for environmental ideas about pollution and toxic contamination.


Types


Detox diets

Detox diets are dietary plans that claim to have
detoxifying Detoxification or detoxication (detox for short) is the physiological or medicinal removal of toxic substances from a living organism, including the human body, which is mainly carried out by the liver. Additionally, it can refer to the period o ...
effects. The general idea suggests that most food contains contaminants: ingredients deemed unnecessary for human life, such as
flavor enhancer A flavoring (or flavouring), also known as flavor (or flavour) or flavorant, is a food additive that is used to improve the taste or smell of food. It changes the perceptual impression of food as determined primarily by the chemoreceptors of t ...
s,
food coloring Food coloring, color additive or colorant is any dye, pigment, or substance that imparts color when it is added to food or beverages. Colorants can be supplied as liquids, powders, gels, or pastes. Food coloring is commonly used in commercia ...
s,
pesticide Pesticides are substances that are used to control pests. They include herbicides, insecticides, nematicides, fungicides, and many others (see table). The most common of these are herbicides, which account for approximately 50% of all p ...
s, and
preservative A preservative is a substance or a chemical that is added to products such as food products, beverages, pharmaceutical drugs, paints, biological samples, cosmetics, wood, and many other products to prevent decomposition by microbial growth or ...
s. Scientists, dietitians, and doctors, while generally viewing brief "detox diets" as harmless (unless
nutritional deficiency Malnutrition occurs when an organism gets too few or too many nutrients, resulting in health problems. Specifically, it is a deficiency, excess, or imbalance of energy, protein and other nutrients which adversely affects the body's tissues a ...
results), often dispute the value and need of "detox diets", due to lack of supporting factual evidence or coherent rationale. In cases where a person suffers from a disease, belief in the efficacy of a detox diet can result in delay or failure to seek effective treatment. Detox diets can involve consuming extremely limited sets of foods (only water or juice, for example, a form of
fasting Fasting is the act of refraining from eating, and sometimes drinking. However, from a purely physiological context, "fasting" may refer to the metabolic status of a person who has not eaten overnight (before "breakfast"), or to the metabolic sta ...
known as
juice fasting Juice fasting, also known as juice cleansing, is a fad diet in which a person consumes only fruit and vegetable juices while abstaining from solid food consumption. It is often used for its presumed detoxification effects as part of an alternativ ...
), eliminating certain foods (such as fats) from the diet, or eliminating
ultra-processed foods An ultra-processed food (UPF) is a grouping of processed food characterized by relatively involved methods of production. There is no simple definition of UPF, but they are generally understood to be an industrial creation derived from natural ...
and alleged irritants. Detox diets are often high in
fiber Fiber (spelled fibre in British English; from ) is a natural or artificial substance that is significantly longer than it is wide. Fibers are often used in the manufacture of other materials. The strongest engineering materials often inco ...
. Proponents claim that this causes the body to burn stored fats, releasing fat-stored "toxins" into the blood, which can then be eliminated through the blood, skin, urine, feces, and breath. Proponents claim that things such as an altered body odor support the notion that detox diets have an effect. The mainstream medical view is that the body has mechanisms to rid itself of toxins, and a
healthy diet A healthy diet is a diet that maintains or improves overall health. A healthy diet provides the body with essential nutrition: fluid, macronutrients such as protein, micronutrients such as vitamins, and adequate fibre and food energy. A he ...
is best for the body. In the short-term, such detox diet may lead to weight loss, due to the strict caloric restriction, however after returning to a normal diet there is a weight gain. Although a brief fast of a single day is unlikely to cause harm, prolonged fasting (as recommended by certain detox diets) can have dangerous health consequences or can even be fatal.


Colon cleansing

Colon cleansing involves administration of an
enema An enema, also known as a clyster, is the rectal administration of a fluid by injection into the Large intestine, lower bowel via the anus.Cullingworth, ''A Manual of Nursing, Medical and Surgical'':155 The word ''enema'' can also refer to the ...
(colonic) containing some salt, and sometimes coffee or
herb Herbs are a widely distributed and widespread group of plants, excluding vegetables, with savory or aromatic properties that are used for flavoring and garnishing food, for medicinal purposes, or for fragrances. Culinary use typically distingu ...
s to remove food that, according to proponents, remains in the colon, producing nonspecific symptoms and general ill-health. However, the colon usually does not require any help cleaning itself. The practice can be potentially dangerous if incorrectly practised.


Heavy metals

Practitioners may recommend detoxification as a treatment to address the notion that
mercury poisoning Mercury poisoning is a type of metal poisoning due to exposure to mercury. Symptoms depend upon the type, dose, method, and duration of exposure. They may include muscle weakness, poor coordination, numbness in the hands and feet, skin rashe ...
arises from consumption of contaminated fish and from dental amalgam fillings –
Quackwatch Quackwatch is a United States-based website focused on promoting consumer protection and providing information about health related frauds, myths, fads, fallacies, and misconduct. It primarily targets alternative medicine, questionable health cl ...
states: "Removing good fillings is not merely a waste of money. In some cases, it results in tooth loss because when fillings are drilled out, some of the surrounding tooth structure will be removed with it."


"Detoxification" devices

Certain devices are promoted to allegedly remove toxins from the body. One version involves a foot-bath using a mild electric current, while another involves small adhesive pads applied to the skin (usually the foot). In both cases, the production of an alleged brown "toxin" appears after a brief delay. In the case of the foot bath, the "toxin" is actually small amounts of
rust Rust is an iron oxide, a usually reddish-brown oxide formed by the reaction of iron and oxygen in the catalytic presence of water or air moisture. Rust consists of hydrous iron(III) oxides (Fe2O3·nH2O) and iron(III) oxide-hydroxide (FeO(OH) ...
ed iron leaching from the electrodes. The adhesive pads change color due to
oxidation Redox ( , , reduction–oxidation or oxidation–reduction) is a type of chemical reaction in which the oxidation states of the reactants change. Oxidation is the loss of electrons or an increase in the oxidation state, while reduction is ...
of the pads' ingredients in response to the skin's moisture. In both cases, the same color changes occur irrespective of whether the water or patch even makes contact with the skin (they merely require water, thus proving the color change does not result from any body detoxification process).


Criticism


Unsound scientific basis

A 2015 review of clinical evidence about detox diets concluded: "At present, there is no compelling evidence to support the use of detox diets for weight management or toxin elimination. Considering the financial costs to consumers, unsubstantiated claims and potential health risks of detox products, they should be discouraged by health professionals and subject to independent regulatory review and monitoring." Detoxification and body cleansing products and diets have been criticized for their unsound scientific basis, in particular their premise of nonexistent "toxins" and their appropriation of the legitimate medical concept of
detoxification Detoxification or detoxication (detox for short) is the physiological or medicinal removal of toxic substances from a living organism, including the human body, which is mainly carried out by the liver. Additionally, it can refer to the period o ...
. According to the
Mayo Clinic Mayo Clinic () is a Nonprofit organization, private American Academic health science centre, academic Medical centers in the United States, medical center focused on integrated health care, healthcare, Mayo Clinic College of Medicine and Science ...
, the "toxins" typically remain unspecified, and there is little to no evidence of toxic accumulation in patients treated. According to a
British Dietetic Association The British Dietetic Association (BDA) is a trade union for dietitians in the United Kingdom. It was founded in 1936 and became a certified union in 1982. It is affiliated to the Trades Union Congress and the Scottish Trades Union Congress. H ...
(BDA) Fact Sheet, "The whole idea of detox is nonsense. The body is a well-developed system that has its own builtin mechanisms to detoxify and remove waste and toxins." It went on to characterize the idea as a "marketing myth", while other critics have called the idea a "scam" and a "hoax". The organization
Sense about Science Sense about Science is a United Kingdom charitable organization that promotes the public understanding of science. Sense about Science was founded in 2002 by Lord Taverne, Bridget Ogilvie and others to promote respect for scientific evidence an ...
investigated "detox" products, calling them a waste of time and money. Resulting in a report that concluded the term is used differently by different companies, most offered no evidence to support their claims, and in most cases its use was the simple renaming of "mundane things, like cleaning or brushing". The human body is naturally capable of maintaining itself, with several organs dedicated to cleansing the
blood Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood is com ...
and the gut. Alan Boobis, a professor and toxicologist at
Imperial College London Imperial College London, also known as Imperial, is a Public university, public research university in London, England. Its history began with Prince Albert of Saxe-Coburg and Gotha, Prince Albert, husband of Queen Victoria, who envisioned a Al ...
, states:
Scientific skeptic Science is a systematic discipline that builds and organises knowledge in the form of testable hypotheses and predictions about the universe. Modern science is typically divided into twoor threemajor branches: the natural sciences, which stu ...
author Brian Dunning investigated the subject in 2008 and concluded that:
Anyone interested in detoxifying their body might think about paying a little more attention to their body and less attention to the people trying to get their money... Why is it that so many people are more comfortable self-medicating for conditions that exist only in advertisements, than they are simply taking their doctor's advice? It's because doctors are burdened with the need to actually practice medicine. They won't hide bad news from you or make up easy answers to please you.
Despite unsound scientific basis, detoxification is popular, and detoxification products and regimes have become a profitable health trend. As with some other alternative medicine treatments, efficacy has been attributed to
astroturfing Astroturfing is the deceptive practice of hiding the Sponsor (commercial), sponsors of an orchestrated message or organization (e.g., political, economic, advertising, religious, or public relations) to make it appear as though it originates from ...
, the
placebo A placebo ( ) can be roughly defined as a sham medical treatment. Common placebos include inert tablets (like sugar pills), inert injections (like saline), sham surgery, and other procedures. Placebos are used in randomized clinical trials ...
effect,
psychosomatic Somatic symptom disorder, also known as somatoform disorder or somatization disorder, is chronic somatization. One or more chronic physical symptoms coincide with excessive and maladaptive thoughts, emotions, and behaviors connected to those symp ...
improvements, or natural recovery from illness that would have occurred without use of the product.


See also

*
List of diets An individual's Diet (nutrition), diet is the sum of food and drink that one habitually consumes. Dieting is the practice of attempting to achieve or maintain a certain weight through diet. People's dietary choices are often affected by a variet ...


References


External links

* {{DEFAULTSORT:Detoxification (Alternative Medicine) Pseudoscience Diets Fasting Fad diets