Tombus virus defective interfering (DI) RNA region 3 is an important

cis-regulatory ''Cis''-regulatory elements (CREs) or ''Cis''-regulatory modules (CRMs) are regions of non-coding DNA which regulate the transcription of neighboring genes. CREs are vital components of genetic regulatory networks, which in turn control morphoge ...

region identified in the

3' UTR In molecular genetics, the three prime untranslated region (3′-UTR) is the section of messenger RNA (mRNA) that immediately follows the translation termination codon. The 3′-UTR often contains regulatory regions that post-transcriptionall ...

of ''

Tombusvirus ''Tombusvirus'' is a genus of viruses, in the family ''Tombusviridae''. Plants serve as natural hosts. There are 17 species in this genus. Symptoms associated with this genus include mosaic. The name of the genus comes from ''Tomato bushy stunt ...

'' defective interfering particles (DI). Defective interfering RNAs are small sub-viral replicons which are non-coding deletion mutants of the virus that maintain cis-acting RNA elements necessary for

replication Replication may refer to: Science * Replication (scientific method), one of the main principles of the scientific method, a.k.a. reproducibility ** Replication (statistics), the repetition of a test or complete experiment ** Replication crisi ...

of the host virus. This conserved region of the 3'UTR has been found to enhance DI RNA accumulation by approximately 10-fold as well as mediating

viral replication Viral replication is the formation of biological viruses during the infection process in the target host cells. Viruses must first get into the cell before viral replication can occur. Through the generation of abundant copies of its genome a ...

References

External links

* Cis-regulatory RNA elements Tombusviridae {{molecular-cell-biology-stub

See also

References

External links