Tom Spies
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Dr. Tom Douglas Spies (September 21, 1902 in Ravenna, Texas – February 28, 1960 in New York City) was a distinguished American physician and medical educator. He was an authority in the study of nutritional diseases. In the 1930s, he contributed significantly to finding a cure for
pellagra Pellagra is a disease caused by a lack of the vitamin niacin (vitamin B3). Symptoms include inflamed skin, diarrhea, dementia, and sores in the mouth. Areas of the skin exposed to friction and radiation are typically affected first. Over tim ...
, a nutritional disease that once afflicted millions in the American South. Later, he also made a large contribution to finding cure for
tropical sprue Tropical sprue is a malabsorption disease commonly found in tropical regions, marked with abnormal flattening of the villi and inflammation of the lining of the small intestine. It differs significantly from coeliac sprue. It appears to be a mor ...
. For his efforts in elimination of pellagra, ''Time'' Magazine named him as 1938 "Man of the Year" in comprehensive science.


Education

A member of
Phi Beta Kappa The Phi Beta Kappa Society () is the oldest academic honor society in the United States. It was founded in 1776 at the College of William & Mary in Virginia. Phi Beta Kappa aims to promote and advocate excellence in the liberal arts and sciences, ...
, Spies received a B.A. degree from the University of Texas in 1923 and an M.D. from Harvard in 1927. He spent the next two years in pathology in Boston hospitals and then went to Western Reserve University to become an instructor in medicine until 1935.


Work

Spies became assistant professor of medicine at the University of Cincinnati's College of Medicine (1935–1947). After 1947, he became an instructor at
Northwestern University Medical School Northwestern or North-western or North western may refer to: * Northwest, a direction * Northwestern University, a private research university in Evanston, Illinois ** The Northwestern Wildcats, this school's intercollegiate athletic program ** No ...
.


Nutrition clinic

Spies was best known as a director of Nutrition Clinic at the Hillman Hospital, Birmingham, Alabama, after 1936. He was invited to come to Birmingham in 1935 by James S. McLester, physician-in-chief of the Hillman Hospital, who was then also the President of the
American Medical Association The American Medical Association (AMA) is an American professional association and lobbying group of physicians and medical students. This medical association was founded in 1847 and is headquartered in Chicago, Illinois. Membership was 271,660 ...
. In 1945, he and six social workers, including Martha Hutchinson, studied the effects of daily supplementation of milk on the growth and development of malnourished children.


Other contributions

Spies was appointed to the Food and Nutrition Board of National Research Council in 1943, and was a consultant on tropical medicine at Washington's Army Medical School, 1945. He labored with unremitting zeal to put
thiamine Thiamine, also known as thiamin and vitamin B1, is a vitamin – an Nutrient#Micronutrients, essential micronutrient for humans and animals. It is found in food and commercially synthesized to be a dietary supplement or medication. Phosp ...
,
nicotinic acid Nicotinic acid, or niacin, is an organic compound and a vitamer of vitamin B3, an essential human nutrient. It is produced by plants and animals from the amino acid tryptophan. Nicotinic acid is also a prescription medication. Amounts f ...
,
riboflavin Riboflavin, also known as vitamin B2, is a vitamin found in food and sold as a dietary supplement. It is essential to the formation of two major coenzymes, flavin mononucleotide and flavin adenine dinucleotide. These coenzymes are involved in ...
,
folic acid Folate, also known as vitamin B9 and folacin, is one of the B vitamins. Manufactured folic acid, which is converted into folate by the body, is used as a dietary supplement and in food fortification as it is more stable during processing and ...
,
vitamin B12 Vitamin B12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. One of eight B vitamins, it serves as a vital cofactor (biochemistry), cofactor in DNA synthesis and both fatty acid metabolism, fatty acid and amino a ...
and
thymine Thymine () (symbol T or Thy) is one of the four nucleotide bases in the nucleic acid of DNA that are represented by the letters G–C–A–T. The others are adenine, guanine, and cytosine. Thymine is also known as 5-methyluracil, a pyrimidine ...
(5-methyl uracil) to use in clinical and preventive medicine. In the late 1940s, Spies experimented with the use of folic acid and other vitamins in the treatment of
tropical sprue Tropical sprue is a malabsorption disease commonly found in tropical regions, marked with abnormal flattening of the villi and inflammation of the lining of the small intestine. It differs significantly from coeliac sprue. It appears to be a mor ...
, which was a deadly disease at that time; he conducted his research in Cuba and Puerto Rico. He received recognition from the Cuban and Puerto Rican governments for his efforts. According to the
American Medical Association The American Medical Association (AMA) is an American professional association and lobbying group of physicians and medical students. This medical association was founded in 1847 and is headquartered in Chicago, Illinois. Membership was 271,660 ...
,
Through his researches, pellagra in the southern United States and tropical sprue in Cuba and Puerto Rico have been virtually eliminated. Perhaps his greatest contribution has been his study of the dietary requirements for the preservation of tissue integrity, whereby premature aging can be prevented.JAMA: DR. SPIES RECEIVES DISTINGUISHED SERVICE MEDAL (1957)
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Honors and awards

* John Phillips Memorial Award of American College of Physicians; * Southern Medical Association Research Medal; * D.Sc., University of the South; * Charles V. Chapin Award (Rhode Island); * Modern Medicine Award for distinguished achievement; * Oscar B. Hunter Award of the American Therapeutic Society; * Recognition by U. S. Congress and Puerto Rico Congress; * Seven decorations and awards from the Government of Cuba; *
American Medical Association The American Medical Association (AMA) is an American professional association and lobbying group of physicians and medical students. This medical association was founded in 1847 and is headquartered in Chicago, Illinois. Membership was 271,660 ...
Distinguished Service Award (1957).


References


PDF file
A biographical sketch by Thomas H. Jukes. Journal of Nutrition, 1972 . NUTRITION, 302: 1395–1400


Footnotes


Bibliography

* Tom Douglas Spies, ''Nutrition and disease'' : special issue from the Department of Nutrition and Metabolism, Northwestern University Medical School, Chicago, Illinois ; Nutrition Clinic, Hillman Hospital, Birmingham, Alabama. Minneapolis : McGraw-Hill, 1955 * Spies, Tom Douglas, ''Rehabilitation through better nutrition''. Philadelphia, Saunders, 1947 * Tom Douglas Spies, ''Vitamins and vitamin deficiencies. Vitamin B12.''. N.Y. 1949. *FROSTIG, J. P., and SPIES, T. D.: ''The initial syndrome of pellagra and associated deficiency diseases''. American Journal of the Medical Sciences 199:268, 1940. *ARING, C. D., EVANS, J. P., and SPIES, T. D.: ''Some Clinical Neurologic Aspects of Vitamin B Deficiencies''. Journal of the American Medical Association 113:2105, 1939. *ARING, C. D., and SPIES, T. D.: ''A Critical Review: Vitamin B Deficiency and Nervous Disease''. Journal of Neurological Psychiatry 2:335, 1939. {{DEFAULTSORT:Spies, Tom Douglas 1902 births 1960 deaths American medical researchers American food scientists American nutritionists Harvard Medical School alumni University of Texas at Austin alumni Vitamin researchers Feinberg School of Medicine faculty