Tight junction protein are
proteins
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respondi ...
that are involved in the formation and functioning of
tight junction
Tight junctions, also known as occluding junctions or ''zonulae occludentes'' (singular, ''zonula occludens''), are multiprotein junctional complexes whose canonical function is to prevent leakage of solutes and water and seals between the epith ...
s; "Tight junction protein" may refer to:
*TJP1,
Tight junction protein 1
Zonula occludens-1 ZO-1, also known as Tight junction protein-1 is a 220-kD peripheral membrane protein that is encoded by the ''TJP1'' gene in humans. It belongs to the family of ''zonula occludens proteins'' (ZO-1, ZO-2, and ZO-3), which are ...
(ZO-1)
*TJP2,
Tight junction protein 2
Tight junction protein ZO-2 is a protein that in humans is encoded by the ''TJP2'' gene.
Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelia ...
(ZO-2)
*TJP3,
Tight junction protein 3 (ZO-3)
See also
*
Gap junction protein Gap junction proteins
;Gap junction α (GJA) proteins
* GJA1, gap junction alpha-1 protein
* GJA2, gap junction alpha-2 protein
* GJA3, gap junction alpha-3 protein
* GJA4, gap junction alpha-4 protein
* GJA5, gap junction alpha-5 protein
* GJA6, ...
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