Thomas Strangeways
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Thomas Strangeways Pigg Strangeways (1866–1926) was a British
pathologist Pathology is the study of disease. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatme ...
, known for founding the Cambridge Research Hospital, which was renamed the
Strangeways Research Laboratory Strangeways Research Laboratory is a research institution in Cambridge, United Kingdom. It was founded by Thomas Strangeways in 1905 as the Cambridge Research Hospital and acquired its current name in 1928. Organised as an independent charity, ...
following Strangeways' death in 1926.


Education and early career

Strangeways was born Thomas Strangeways Pigg in 1866. Strangeways studied under
Alfredo Kanthack Alfredo Kanthack (1863-1898) was a Brazilian-born microbiologist and pathologist who worked in England. His distinguished career was cut short by his premature death at the age of 35. Early life Alfredo Antunes Kanthack was born on 4 March 1863 ...
at
St Bartholomew's Hospital St Bartholomew's Hospital, commonly known as Barts, is a teaching hospital located in the City of London. It was founded in 1123 by Rahere, and is currently run by Barts Health NHS Trust. History Early history Barts was founded in 1123 by ...
and received his medical degree in 1890. He followed Kanthack to the
University of Cambridge The University of Cambridge is a Public university, public collegiate university, collegiate research university in Cambridge, England. Founded in 1209, the University of Cambridge is the List of oldest universities in continuous operation, wo ...
after Kanthack was offered the chair of the Pathology Department there. Strangeways became a demonstrator and subsequently a lecturer in pathology at the University of Cambridge.


Founding of Cambridge Research Hospital

Strangeways developed an interest in the pathology of
rheumatoid arthritis Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects synovial joint, joints. It typically results in warm, swollen, and painful joints. Pain and stiffness often worsen following rest. Most commonly, the wrist and h ...
and in 1905 founded the Cambridge Research Hospital in order to study patients with this condition and related ones. Funded largely by Strangeways himself, noted doctors of his acquaintance, and donations from patients, the hospital began modestly with only six beds, and with research equipment located in renovated coal sheds. It closed briefly in 1908 due to lack of funding, but quickly reopened and moved to its current site in 1912 thanks to the support of
Otto Beit Sir Otto John Beit, 1st Baronet, KCMG, FRS (7 December 1865 – 7 December 1930) was a German-born British financier, philanthropist and art connoisseur. Life history and career Beit was born in Hamburg, Germany, the younger brother of Alfr ...
and to its temporary repurposing as a hospital for military officers in
World War I World War I or the First World War (28 July 1914 – 11 November 1918), also known as the Great War, was a World war, global conflict between two coalitions: the Allies of World War I, Allies (or Entente) and the Central Powers. Fighting to ...
. The hospital returned to its research purpose in 1917. Later, in 1923, the clinical aspects of the laboratory's work were moved back to
St Bartholomew's Hospital St Bartholomew's Hospital, commonly known as Barts, is a teaching hospital located in the City of London. It was founded in 1123 by Rahere, and is currently run by Barts Health NHS Trust. History Early history Barts was founded in 1123 by ...
so that the laboratory could focus on then-newly developing technologies in
tissue culture Tissue culture is the growth of tissue (biology), tissues or cell (biology), cells in an artificial medium separate from the parent organism. This technique is also called micropropagation. This is typically facilitated via use of a liquid, semi-s ...
and
cell biology Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living an ...
. Having learned about tissue culture techniques from
Alexis Carrel Alexis Carrel (; 28 June 1873 – 5 November 1944) was a French surgeon and biologist who spent most of his scientific career in the United States. He was awarded the Nobel Prize in Physiology or Medicine in 1912 for pioneering vascular suturi ...
, Strangeways took great interest in the new field, including developing demonstrations of the technique for his lectures. After
University of Edinburgh The University of Edinburgh (, ; abbreviated as ''Edin.'' in Post-nominal letters, post-nominals) is a Public university, public research university based in Edinburgh, Scotland. Founded by the City of Edinburgh Council, town council under th ...
zoology Zoology ( , ) is the scientific study of animals. Its studies include the anatomy, structure, embryology, Biological classification, classification, Ethology, habits, and distribution of all animals, both living and extinction, extinct, and ...
student
Honor Fell Dame Honor Bridget Fell, DBE, FRS (22 May 1900 – 22 April 1986) was a British scientist and zoologist. Her contributions to science included the development of experimental methods in organ culture, tissue culture, and cell biology. Early l ...
spent a summer working with him, he hired her as a research assistant; she would take over leadership of the laboratory following Strangeways' death in 1926. In the 1920s and 30s, the laboratory was the only British institution focused specifically on tissue culture technique, the utility of which was a controversial topic among scientists of the time.


Personal life

Strangeways became engaged to Dorothy Beck in 1901 and the couple married in 1902. As of the construction of the new hospital building in 1912, they had two children. Strangeways financed his laboratory out of his own earnings for most of his life, although he was not personally wealthy; a later director of the laboratory, John Dingle, wrote in a retrospective that "there is little doubt that his family suffered financially" from his investments, although Dorothy was consistently supportive of the project. Strangeways died unexpectedly of a
brain haemorrhage Intracerebral hemorrhage (ICH), also known as hemorrhagic stroke, is a sudden bleeding into the tissues of the brain (i.e. the parenchyma), into its ventricles, or into both. An ICH is a type of bleeding within the skull and one kind of stro ...
in 1926.


See also

*
David Strangeways David Inderwick Strangeways DSO, OBE (26 February 19121 August 1998) was a colonel in the British Army who helped organise several military deceptions during World War II. After leaving the army in 1957, he took holy orders.


References

{{DEFAULTSORT:Strangeways, Thomas
British pathologists 1866 births 1926 deaths