Thomas S. Ray
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Thomas S. Ray (born September 21, 1954) is an American evolutionary biologist known for his research in tropical biology, digital evolution, and the human mind.


Early life and education

Ray earned his undergraduate degrees in biology and chemistry at
Florida State University Florida State University (FSU or Florida State) is a Public university, public research university in Tallahassee, Florida, United States. It is a senior member of the State University System of Florida and a preeminent university in the s ...
. He then proceeded to
Harvard University Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyma ...
, where he received his master's and Doctorate i
Biology
specializing in plant behavior.


Career

Ray began his career as a member of th
Society of Fellows
at the
University of Michigan The University of Michigan (U-M, U of M, or Michigan) is a public university, public research university in Ann Arbor, Michigan, United States. Founded in 1817, it is the oldest institution of higher education in the state. The University of Mi ...
at
Ann Arbor Ann Arbor is a city in Washtenaw County, Michigan, United States, and its county seat. The 2020 United States census, 2020 census recorded its population to be 123,851, making it the List of municipalities in Michigan, fifth-most populous cit ...
, and in 1981 joined the faculty of the University of Delaware'sbr>School of Life and Health Sciences
In 1993 he received a joint appointment i
Computer and Information Science
at U. Delaware while also being appointed to the External Faculty of th
Santa Fe Institute
In August 1993 he started a position as an invited researcher in th

Human Information Processing Research Labs Evolutionary Systems Department. In 1998 Ray became a Professor in the Zoology (late
Biology

Computer Science
departments at the
University of Oklahoma The University of Oklahoma (OU) is a Public university, public research university in Norman, Oklahoma, United States. Founded in 1890, it had existed in Oklahoma Territory near Indian Territory for 17 years before the two territories became the ...
. Ray retired from the University of Oklahoma in 2021. Throughout his career he has studied different disciplines: * Tropical Biology (1974 - 1989) where he focused on foraging behavior among vines primarily located throughout
Costa Rica Costa Rica, officially the Republic of Costa Rica, is a country in Central America. It borders Nicaragua to the north, the Caribbean Sea to the northeast, Panama to the southeast, and the Pacific Ocean to the southwest, as well as Maritime bo ...
. *
Artificial Life Artificial life (ALife or A-Life) is a field of study wherein researchers examine systems related to natural life, its processes, and its evolution, through the use of simulations with computer models, robotics, and biochemistry. The discipline ...
(1990 -2001) which delved into digital
evolution Evolution is the change in the heritable Phenotypic trait, characteristics of biological populations over successive generations. It occurs when evolutionary processes such as natural selection and genetic drift act on genetic variation, re ...
by
natural selection Natural selection is the differential survival and reproduction of individuals due to differences in phenotype. It is a key mechanism of evolution, the change in the Heredity, heritable traits characteristic of a population over generation ...
via the Tierra system. * Architecture of the Human
Mind The mind is that which thinks, feels, perceives, imagines, remembers, and wills. It covers the totality of mental phenomena, including both conscious processes, through which an individual is aware of external and internal circumstances ...
(Current) investigating
mental disorders A mental disorder, also referred to as a mental illness, a mental health condition, or a psychiatric disability, is a behavioral or mental pattern that causes significant distress or impairment of personal functioning. A mental disorder is ...
,
evolvability Evolvability is defined as the capacity of a system for adaptive evolution. Evolvability is the ability of a population of organisms to not merely generate genetic diversity, but to generate '' adaptive'' genetic diversity, and thereby evolve thr ...
,
consciousness Consciousness, at its simplest, is awareness of a state or object, either internal to oneself or in one's external environment. However, its nature has led to millennia of analyses, explanations, and debate among philosophers, scientists, an ...
, and molecular mental mechanisms as they relate to neurochemical interactions with psychoactive drugs.
Mindstate Design Labs
– as the scientific founder of Mindstate Design Labs, Ray researches psychoactive drugs to explore the chemical architecture of the human mind, proposing "mental organs" with specific neurotransmitter receptors that contribute to mental states and mental disorders.


Tropical biology

From 1974 to 1989, Ray worked as a tropical biologist, studying the evolution, ecology, and natural history of various organisms inhabiting rain forests. His research primarily focused on the foraging behavior of vines in the
Araceae The Araceae are a family of monocotyledonous flowering plants in which flowers are borne on a type of inflorescence called a spadix. The spadix is usually accompanied by, and sometimes partially enclosed in, a spathe (or leaf-like bract). Also ...
family, but also included studies on ants, butterflies, and beetle

Ray conducted most of his field work in
Costa Rica Costa Rica, officially the Republic of Costa Rica, is a country in Central America. It borders Nicaragua to the north, the Caribbean Sea to the northeast, Panama to the southeast, and the Pacific Ocean to the southwest, as well as Maritime bo ...
, where he established the Finca El Bejuco biological station in the northern lowland rain forests. He continues to own and operate this station and remains deeply involved in rain forest conservation in Costa Rica.


Artificial life and digital evolution

In 1990, Ray turned his attention to
artificial life Artificial life (ALife or A-Life) is a field of study wherein researchers examine systems related to natural life, its processes, and its evolution, through the use of simulations with computer models, robotics, and biochemistry. The discipline ...
, exploring the outcomes of evolution by natural selection within digital computatio

This work began with the creation of Tierra, a system in which Self-replication, self-replicating
machine code In computer programming, machine code is computer code consisting of machine language instructions, which are used to control a computer's central processing unit (CPU). For conventional binary computers, machine code is the binaryOn nonb ...
programs evolve by
natural selection Natural selection is the differential survival and reproduction of individuals due to differences in phenotype. It is a key mechanism of evolution, the change in the Heredity, heritable traits characteristic of a population over generation ...
. His work in this field has attracted significant media attentio

In 2000, he implemented a new system calle
Virtual Life
building upon Evolved Virtual Creatures, a concept originally created by
Karl Sims Karl Sims (born 1962) is a computer graphics artist and researcher, who is best known for using particle systems and artificial life in computer animation. Biography Sims received a B.S. in Life Sciences from MIT in 1984, and a M.S. in computer g ...
. In 2003, Ray collaborated with Ivan Tanev to further develop the Virtual Life project.


Architecture of the Human Mind

The research conducted by T.S. Ray has substantially contributed to our understanding of the human mind, consciousness, and the effects of psychoactive substances. He has hypothesized that the human mind is composed of "mental organs," which are populations of neurons bearing a specific G-protein-coupled receptor (GPCR) (and other
metabotropic receptors A metabotropic receptor, also referred to by the broader term G-protein-coupled receptor, is a type of membrane receptor that initiates a number of metabolic steps to modulate cell activity. The nervous system utilizes two types of receptors: meta ...
) on their surface. These mental organs are thought to provide a direct link between mental properties—such as joy, consciousness, and reason—and the genes and regulatory elements associated with GPCR. Importantly, because there is heritable genetic variation associated with these mental organs, they can evolve over time. Ray's studies on psychedelic drugs have further elaborated on this theory. His research posits that the diverse effects of these substances can be attributed to their interactions with different mental organs. The breadth of these interactions is significant, with psychoactive substances showing activity across a wide range of receptor sites. This interaction pattern supports the idea that the diversity in effects of these drugs is likely due to their diverse interactions with different mental organs, emphasizing the roles of dozens of different receptors. The theory also offers a fresh perspective on the effects of MDMA, a drug that is known for its unique
entactogenic Entactogens, also known as empathogens or connectogens, are a class of psychoactive drugs that induce the production of experiences of emotional communion, oneness, connectedness, emotional openness—that is, empathy—as particularly observe ...
mental state. Traditional views suggest that MDMA's effects are primarily due to neurotransmitter release, especially serotonin. However, Ray proposes an alternative hypothesis: the distinctive mental state caused by MDMA arises from the simultaneous direct activation of imidazoline-1 (I1) and serotonin-2 (5-HT2) receptors, which correspond to specific mental organs. According to this theory, a mental organ can only enter consciousness if two things occur: the mental organ is directly activated at its defining receptor, and 5-HT2 is simultaneously activated. To test these hypotheses, Ray has proposed the "primer/probe" metho

A "primer" is a drug that selectively activates certain serotonin receptors, while a "probe" is a drug that activates a non-serotonin receptor corresponding to the mental organ that researchers want to bring into consciousness for study. By using both a primer and a probe, it is possible to load a mental organ into consciousness and thus study its role in the mind. Taken together, this body of research provides an innovative framework for understanding the human mind, consciousness, and the effects of psychoactive substances, suggesting a direct linkage between mental properties, neuronal structures, and genetic component


Mindstate Design Labs

Currently, Ray is the scientific founder o
Mindstate Design Labs
where his research revolves around Psychoactive_drug, psychoactive drugs as tools for probing the chemical architecture of the human
mind The mind is that which thinks, feels, perceives, imagines, remembers, and wills. It covers the totality of mental phenomena, including both conscious processes, through which an individual is aware of external and internal circumstances ...
. He proposes the existence of "mental organs", defined as populations of
neurons A neuron (American English), neurone (British English), or nerve cell, is an membrane potential#Cell excitability, excitable cell (biology), cell that fires electric signals called action potentials across a neural network (biology), neural net ...
bearing specific neurotransmitter receptors on their surface. Ray's work aims to use the diversity of mental organs to discover, design, and create diverse mental states.


Academic appointments

Over the years, Ray has held several academic positions. In 1981, he joined the faculty of the
University of Delaware The University of Delaware (colloquially known as UD, UDel, or Delaware) is a Statutory college#Delaware, privately governed, state-assisted Land-grant university, land-grant research university in Newark, Delaware, United States. UD offers f ...

School of Life and Health Sciences
In 1993, he received a joint appointment i
Computer and Information Science
at the University of Delaware and was appointed to the External Faculty of th
Santa Fe Institute
Later that year, he joined the Evolutionary Systems Department a

Human Information Processing Research Labs in Japan as an invited researcher. In August 1998, he became a Professor of Zoology (late
Biology
at the
University of Oklahoma The University of Oklahoma (OU) is a Public university, public research university in Norman, Oklahoma, United States. Founded in 1890, it had existed in Oklahoma Territory near Indian Territory for 17 years before the two territories became the ...
, with an adjunct appointment as a Professor o
Computer Science


Tierra Software

Tierra is a computer program developed by Dr. Thomas S. Ray in the early 1990s. This innovative software allowed computer programs to compete for time ( central processing unit (CPU) time) and space (access to main memory). Within the Tierra
virtual machine In computing, a virtual machine (VM) is the virtualization or emulator, emulation of a computer system. Virtual machines are based on computer architectures and provide the functionality of a physical computer. Their implementations may involve ...
, these computer programs are evolvable and capable of Self-replication, self-replicating and recombining. The virtual machine of Tierra is written in C and operates on a custom machine instruction set designed to facilitate code changes and reordering, featuring elements such as "jump to template" as opposed to the relative or absolute jumps common to most instruction sets. The Tierra model has been utilized to explore the fundamental processes of evolutionary and ecological dynamics in a computational environment. It facilitates the investigation of processes such as the dynamics of
punctuated equilibrium In evolutionary biology, punctuated equilibrium (also called punctuated equilibria) is a Scientific theory, theory that proposes that once a species appears in the fossil record, the population will become stable, showing little evolution, evol ...
, host-parasite co-evolution, and density-dependent natural selection. Unlike more conventional models of
evolutionary computation Evolutionary computation from computer science is a family of algorithms for global optimization inspired by biological evolution, and the subfield of artificial intelligence and soft computing studying these algorithms. In technical terms ...
, such as
genetic algorithms In computer science and operations research, a genetic algorithm (GA) is a metaheuristic inspired by the process of natural selection that belongs to the larger class of evolutionary algorithms (EA). Genetic algorithms are commonly used to g ...
, Tierra does not have an explicit, or exogenous,
fitness function A fitness function is a particular type of objective or cost function that is used to summarize, as a single figure of merit, how close a given candidate solution is to achieving the set aims. It is an important component of evolutionary algorit ...
built into the model. The fitness function in Tierra is endogenous, with survival and death being the core factors determining the "fitness" of a program, resulting in an instance of natural selection. According to Ray and other researchers, this setup might allow for more "open-ended" evolution, in which the feedback dynamics between evolutionary and ecological processes can change over time. However, this claim is yet to be realized. Like other digital evolution systems, Tierra eventually reaches a point where novelty ceases to be created, and the system at large either begins looping or ceases to 'evolve'. The challenge of implementing true open-ended evolution in an artificial system is an ongoing question in the field of artificial life. Researchers
Mark Bedau Mark A. Bedau is an American philosopher who works in the field of artificial life. He is the son of the philosopher Hugo Bedau (1926–2012). Mark Bedau earned his B.A. in philosophy at Reed College in 1977, and his Ph.D. in Philosophy from Univer ...
and
Norman Packard Norman Harry Packard (born 1954 in Billings, Montana) is a chaos theory physicist and one of the founders of the Prediction Company and ProtoLife. He is an alumnus of Reed College, with a PhD from the University of California, Santa Cruz. Packard ...
developed a statistical method of classifying evolutionary systems. In 1997, they applied these statistics to Evita, an artificial life model like Tierra and
Avida Avida may refer to: * Avida (software), artificial life software platform * ''Avida'' (film), 2006 French film * Avida, the former name of the kibbutz Neve Harif * Mordechai Avida, Israeli radio broadcaster See also * Abida (biblical figure) ...
, concluding that Tierra-like systems do not exhibit the open-ended evolutionary signatures of naturally evolving systems. Similarly, Russell K. Standish measured the informational complexity of 'organisms' within Tierra and did not observe complex growth in their evolution.


Personal life

Ray was born in Norman Oklahoma. He has a daughter named Ariel Ivy Ray who was born in 1993.


Sample of Publications

Strong, D. R. and T. S. Ray. 1975. Host tree location behavior of a tropical vine (Monstera gigantea) by skototropism. Science, 190: 804–06

Ray, T. S., and C. C. Andrews. 1980. Antbutterflies: Butterflies that follow army ants to feed on antbird droppings. Science 210: 1147–1148

Ray, T. S. 1980. Syngonium oduberi (Araceae): A new species from the Osa Peninsula of Costa Rica. Aroideana 3(4): 128–129

Ray, T. S. 1983. Monstera tenuis. In D. Janzen d. Costa Rican natural history, 278–80. University of Chicago Press

Ray, T. S. 1985. The host plant, Erythroxylum (Erythroxylaceae), of Agrias (Nymphalidae). J. Lep. Soc. 39(4):266–267

Ray, T. S. 1988. Diversification of growth habits in the Araceae. Amer. J. Bot.76(Suppl.): 276. Ray, T. S. 1990. Metamorphosis in the Araceae. Amer. J. Bot. 77(12): 1599–1609.

Ray, T. S. 1991. Evolution and optimization of digital organisms. In: Billingsley K. R., E. Derohanes, H. Brown, III ds. Scientific Excellence in Supercomputing: The IBM 1990 Contest Prize Papers, Athens, GA, 30602: The Baldwin Press, The University of Georgia. Publication date: December 1991, Pp. 489–531. Ray, T. S. 1991. An approach to the synthesis of life. In : Langton, C., C. Taylor, J. D. Farmer, & S. Rasmussen ds Artificial Life II, Santa Fe Institute Studies in the Sciences of Complexity, vol. XI, 371–408. Redwood City, CA: Addison-Wesley.

Ray, T. S. 1992. Foraging behaviour in tropical herbaceous climbers (Araceae). Journal of Ecology 80: 189–203

Ray, T. S. 1994. An evolutionary approach to synthetic biology: Zen and the art of creating life. Artificial Life 1(1/2): 195–226. Reprinted In: Langton, C. G. d. Artificial Life, an overview. The MIT Press, 1995

Ray, T. S. 1994. Evolution, complexity, entropy, and artificial reality. Physica D 75: 239–263.

Thearling, Kurt, and Thomas S. Ray. 1997. “Evolving Parallel Computation,” Complex Systems, 10(3):229–237. (June 1996

Ray, T. S. 1998. Selecting Naturally for Differentiation: preliminary evolutionary results. Complexity, 3(5): 25–33. John Wiley & Sons, Inc

Ray, T. S. 2001. Aesthetically Evolved Virtual Pets. Leonardo 34(4): 313–316.

Ray, T. S. 2002. Kurzweil’s Turing Fallacy. In: Jay Wesley Richards d. “Are We Spiritual Machines?: Ray Kurzweil vs. the Critics of Strong AI”, with George Gilder, Ray Kurzweil, William Dembski, John Searle, Michael Denton and Thomas Ray. Discovery Institute, Seattle. Pp. 116–127

Ray, T.S. 2010. Psychedelics and the Human Receptorome. PLoS ONE.

February 2, 2010. Ray, T. S. 2012. Mental Organs and the Origins of Mind. In: L. Swan (Ed) Origins of Mind, pp. 301–326. New York / Heidelberg: Springer.

Ray, T. S. 2015. Constructing the ecstasy of MDMA from its component mental organs: Proposing the primer/probe method. Medical Hypotheses / Elsevier, 87, 48 – 60

Ray, T.S. 2017. Mental Organs and the Breadth and Depth of Consciousness. Transform Press. June 27, 2017


External links


Tom Ray’s Personal Home Page

VirtualLife project

Publications on Tropical Biology

Artificial Life Publications

Publications on the human mind


References

{{DEFAULTSORT:Ray, Thomas S. 1954 births American ecologists 21st-century American zoologists Researchers of artificial life University of Oklahoma faculty University of Delaware faculty Florida State University alumni Harvard University alumni Living people