Thomas P. Loughran, Jr. is an American physician-scientist who specializes in

cancer Cancer is a group of diseases involving Cell growth#Disorders, abnormal cell growth with the potential to Invasion (cancer), invade or Metastasis, spread to other parts of the body. These contrast with benign tumors, which do not spread. Po ...

research and treatment. He became director of the

University of Virginia Cancer Center University of Virginia Cancer Center is a National Cancer Institute-designated Comprehensive Cancer Center affiliated with the University of Virginia School of Medicine and the UVA Health System. Focused on research and education, UVA Cancer Cen ...

, F. Palmer Weber-Smithfield Foods Professor of Oncology Research and Professor of Medicine at the

University of Virginia The University of Virginia (UVA) is a Public university#United States, public research university in Charlottesville, Virginia, United States. It was founded in 1819 by Thomas Jefferson and contains his The Lawn, Academical Village, a World H ...

on August 15, 2013. Between 2003 and 2013, Loughran served as the founding director of the Penn State Hershey Cancer Institute and professor of medicine at the

Penn State College of Medicine The Pennsylvania State College of Medicine (PSCOM) is the medical school of Pennsylvania State University, a public university system in Pennsylvania. It is located in Hershey near the Penn State Milton S. Hershey Medical Center and Penn State H ...

. His previous appointments included program leader of hematologic malignancies at the H. Lee Moffitt Cancer Center & Research Institute at the University of South Florida, associate director of the Bone Marrow Transplant Program at SUNY Health Science Center and chief of hematology at the Syracuse Veteran's Affairs Medical Center in Syracuse, New York. Loughran completed his fellowship in medical oncology in 1985 at the

Fred Hutchinson Cancer Research Center The Fred Hutchinson Cancer Center, formerly known as the Fred Hutchinson Cancer Research Center and also known as Fred Hutch or The Hutch, is a cancer research institute established in 1975 in Seattle, Washington (state), Washington. History ...

Seattle Seattle ( ) is the most populous city in the U.S. state of Washington and in the Pacific Northwest region of North America. With a population of 780,995 in 2024, it is the 18th-most populous city in the United States. The city is the cou ...

Washington Washington most commonly refers to: * George Washington (1732–1799), the first president of the United States * Washington (state), a state in the Pacific Northwest of the United States * Washington, D.C., the capital of the United States ** A ...

under direction of Nobel Laureate E. Donnall Thomas. He remained on faculty there for seven years. Loughran earned his medical degree from Hahnemann Medical School in

Philadelphia Philadelphia ( ), colloquially referred to as Philly, is the List of municipalities in Pennsylvania, most populous city in the U.S. state of Pennsylvania and the List of United States cities by population, sixth-most populous city in the Unit ...

in 1979.

LGL leukemia research

Loughran's primary research interest is large granular lymphocyte leukemia (LGL), a hematologic malignancy he discovered in the mid-1980s. He is considered the international expert on this form of leukemia. He has received continuous federal grant support for the past 26 years and currently is the principal investigator on two R01 grants and a P01 grant from the

National Cancer Institute The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. ...

, as well as a translational research grant from the

Leukemia & Lymphoma Society The Leukemia & Lymphoma Society (LLS), a 501(c)(3) charitable organization founded in 1949, is a voluntary health organization dedicated to fighting blood cancer world-wide. LLS funds blood cancer research on cures for leukemia, lymphoma, Hodgkin ...

. Loughran has published numerous articles in high impact peer-reviewed journals including

The New England Journal of Medicine ''The New England Journal of Medicine'' (''NEJM'') is a weekly medical journal published by the Massachusetts Medical Society. Founded in 1812, the journal is among the most prestigious peer-reviewed medical journals. Its 2023 impact factor w ...

Annals of Internal Medicine ''Annals of Internal Medicine'' is an academic medical journal published by the American College of Physicians (ACP). It is one of the most widely cited and influential specialty medical journals in the world. ''Annals'' publishes content releva ...

The Lancet ''The Lancet'' is a weekly peer-reviewed general medical journal, founded in England in 1823. It is one of the world's highest-impact academic journals and also one of the oldest medical journals still in publication. The journal publishes ...

Journal of Clinical Investigation The ''Journal of Clinical Investigation'' is a semi-monthly peer-reviewed medical journal covering biomedical research. It was established in 1924 and is published by the American Society for Clinical Investigation. Articles focus on the mechanisms ...

Journal of Clinical Oncology The ''Journal of Clinical Oncology'' is a peer-reviewed medical journal published 3 times a month by ASCO Publications. It covers research on all aspects of clinical oncology. The journal was established in 1983 and the editor-in-chief is Jonat ...

, and

Blood Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood is com ...

. Loughran holds American Board certifications in

internal medicine Internal medicine, also known as general medicine in Commonwealth nations, is a medical specialty for medical doctors focused on the prevention, diagnosis, and treatment of diseases in adults. Its namesake stems from "treatment of diseases of ...

and

medical oncology Oncology is a branch of medicine that deals with the study, treatment, diagnosis, and prevention of cancer. A medical professional who practices oncology is an ''oncologist''. The name's etymological origin is the Greek word ὄγκος (''� ...

. In his clinical practice, he treats patients with bone marrow disorders and leukemia.

References

External links

UVA Health System Doctor Profile

Official Loughran Lab Website
{{DEFAULTSORT:Loughran, Thomas P., Jr. Year of birth missing (living people) Living people American cancer researchers University of Virginia School of Medicine faculty Drexel University alumni Fred Hutchinson Cancer Research Center people