Thomas Jessell
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Thomas Michael Jessell (2 August 1951 – 28 April 2019) was the Claire Tow Professor of
biochemistry Biochemistry, or biological chemistry, is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology, a ...
and molecular biophysics at
Columbia University Columbia University in the City of New York, commonly referred to as Columbia University, is a Private university, private Ivy League research university in New York City. Established in 1754 as King's College on the grounds of Trinity Churc ...
in New York and a prominent developmental neuroscientist. In 2018, Columbia University announced his termination from his administrative positions after an internal investigation uncovered violations of university policies. He died shortly after from a rapidly neurodegenerative condition diagnosed as
progressive supranuclear palsy Progressive supranuclear palsy (PSP) is a late-onset neurodegenerative disease involving the gradual deterioration and death of specific volumes of the brain, linked to 4-repeat tau pathology. The condition leads to symptoms including Balance di ...
.


Education

Jessell received his PhD in neuroscience from the
University of Cambridge The University of Cambridge is a Public university, public collegiate university, collegiate research university in Cambridge, England. Founded in 1209, the University of Cambridge is the List of oldest universities in continuous operation, wo ...
PhD in 1977 with Leslie Iversen at the MRC Neurochemical Pharmacology Unit.


Career and research

After his PhD, he worked as a
postdoctoral A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). Postdocs most commonly, but not always, have a temporary acade ...
fellow at
Harvard Medical School Harvard Medical School (HMS) is the medical school of Harvard University and is located in the Longwood Medical and Academic Area, Longwood Medical Area in Boston, Massachusetts. Founded in 1782, HMS is the third oldest medical school in the Un ...
with Gerald Fischbach. In 1981 he became an assistant professor in the Department of Neurobiology at
Harvard Medical School Harvard Medical School (HMS) is the medical school of Harvard University and is located in the Longwood Medical and Academic Area, Longwood Medical Area in Boston, Massachusetts. Founded in 1782, HMS is the third oldest medical school in the Un ...
. In 1985 he joined the
Columbia University Columbia University in the City of New York, commonly referred to as Columbia University, is a Private university, private Ivy League research university in New York City. Established in 1754 as King's College on the grounds of Trinity Churc ...
faculty where he worked for the remainder of his career and became Claire Tow Professor of Motor Neuron Disorders (in neuroscience). Jessell is known for his work on chemical
signals A signal is both the process and the result of Signal transmission, transmission of data over some transmission media, media accomplished by embedding some variation. Signals are important in multiple subject fields including signal processin ...
that play a role when
nerve cell A neuron (American English), neurone (British English), or nerve cell, is an excitable cell that fires electric signals called action potentials across a neural network in the nervous system. They are located in the nervous system and help to ...
s assemble during
development Development or developing may refer to: Arts *Development (music), the process by which thematic material is reshaped * Photographic development *Filmmaking, development phase, including finance and budgeting * Development hell, when a proje ...
to form neuronal circuits. In 1994, he showed that netrin guides commissural axons in the vertebrate spinal cord.


Awards

In 1994 Jessell was awarded the
NAS Award for Scientific Reviewing The NAS Award for Scientific Reviewing is awarded by the United States National Academy of Sciences, U.S. National Academy of Sciences (NAS) "to recognize authors whose reviews have synthesized extensive and difficult material, rendering a signific ...
from the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, NGO, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the ...
. He was a co-recipient, with Pasko Rakic and Sten Grillner, of the inaugural Kavli Prize for Neuroscience in 2008. He was elected a
Fellow of the Royal Society Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the Fellows of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural science, natural knowledge, incl ...
in 1996. He won the Ralph W. Gerard Prize from the Society for Neuroscience in 2016. He was a fellow of the
Norwegian Academy of Science and Letters The Norwegian Academy of Science and Letters (, DNVA) is a learned society based in Oslo, Norway. Its purpose is to support the advancement of science and scholarship in Norway. History The Royal Frederick University in Christiania was establis ...
.


Books

Jessell is the co-editor, with Eric R. Kandel and James Schwartz, of the well-known textbook Principles of Neural Science.


Misconduct investigation and firing

On March 7, 2018, Jessell was removed from his post at Columbia University following what a Columbia statement described as "an investigation that revealed serious violations of university policies and values governing the behavior of faculty members in an academic environment". The university did not give details of the nature of the violations. His appointment as an investigator at the
Howard Hughes Medical Institute The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization headquartered in Chevy Chase, Maryland with additional facilities in Ashburn, Virginia. It was founded in 1953 by Howard Hughes, an American busin ...
, which he had held since 1985, was also ended. The ''
Columbia Daily Spectator The ''Columbia Daily Spectator'' (known colloquially as ''Spec'') is the student newspaper of Columbia University. Founded in 1877, it is the second-oldest continuously operating college news daily in the nation after '' The Harvard Crimson'', a ...
'' reported on April 12 that Jessell "was engaged in a relationship with a lab member under his supervision for years, violating University policies on consensual romantic and sexual relationships, before being removed from all administrative posts this past March". The newspaper subsequently reported that Jessell "was removed from his administrative post, following an investigation that found him responsible for sexual misconduct". It is reported Jessell was suffering symptoms of an aggressive neurodegenerative disease during this period.


References


External links


Jessell's Faculty Profile
{{DEFAULTSORT:Jessell, Thomas 1951 births 2019 deaths 20th-century American biochemists Columbia University faculty Columbia Medical School faculty British emigrants to the United States Foreign associates of the National Academy of Sciences Fellows of the Royal Society Howard Hughes Medical Investigators Kavli Prize laureates in Neuroscience Members of the Norwegian Academy of Science and Letters Members of the National Academy of Medicine 21st-century American biochemists People with rare diseases Deaths from neurodegenerative disease