In
enzymology
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
, a thiocyanate hydrolase () is an
enzyme that
catalyzes
Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recyc ...
the
chemical reaction
:thiocyanate + 2 H
2O
carbonyl sulfide + NH
3 + HO-
Thus, the two
substrates of this enzyme are
thiocyanate and
H2O, whereas its 3
products are
carbonyl sulfide,
NH3, and
HO-.
This enzyme belongs to the family of
hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in nitriles. The
systematic name of this enzyme class is thiocyanate aminohydrolase.
Structural studies
As of late 2007, 4
structures have been solved for this class of enzymes, with
PDB accession codes , , , and .
References
*
*
EC 3.5.5
Enzymes of known structure
{{3.5-enzyme-stub