Thiochrome (TChr)is a tricyclic
organic compound
Some chemical authorities define an organic compound as a chemical compound that contains a carbon–hydrogen or carbon–carbon bond; others consider an organic compound to be any chemical compound that contains carbon. For example, carbon-co ...
that arises from the oxidation of the vitamin
thiamine
Thiamine, also known as thiamin and vitamin B1, is a vitamin – an Nutrient#Micronutrients, essential micronutrient for humans and animals. It is found in food and commercially synthesized to be a dietary supplement or medication. Phosp ...
. Being highly fluorescent, it is often the derivative that is quantified in the analysis of thiamine. The oxidation can be effected with
ceric ammonium nitrate
Ceric ammonium nitrate (CAN) is the inorganic compound with the formula . This orange-red, water-soluble cerium salt is a specialised oxidizing agent in organic synthesis and a standard oxidant in quantitative analysis.
Preparation, properties, ...
,
hydrogen peroxide
Hydrogen peroxide is a chemical compound with the formula . In its pure form, it is a very pale blue liquid that is slightly more viscosity, viscous than Properties of water, water. It is used as an oxidizer, bleaching agent, and antiseptic, usua ...
, and related reagents. Hydrolysis of thiamine can yield a thiol derivative (TSH), which is also susceptible to oxidation to the
disulfide
In chemistry, a disulfide (or disulphide in British English) is a compound containing a functional group or the anion. The linkage is also called an SS-bond or sometimes a disulfide bridge and usually derived from two thiol groups.
In inorg ...
(TSST).
[{{cite journal , doi=10.1016/j.plefa.2004.10.009, title=Thiamine and vasculopathies , year=2005 , last1=Stepuro , first1=I.I. , journal=Prostaglandins, Leukotrienes and Essential Fatty Acids , volume=72 , issue=2 , pages=115–127 , pmid=15626594 ]
References
Primary alcohols
Thiazoles
Heterocyclic compounds with 3 rings