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Thiobarbital is a drug which is a
It is of note that although the drug can be prepared by the above route (cf e.g.
barbiturate
Barbiturates are a class of depressant drugs that are chemically derived from barbituric acid. They are effective when used medically as anxiolytics, hypnotics, and anticonvulsants, but have physical and psychological addiction potential as we ...
derivative. It is the thiobarbiturate analogue of barbital.
Synthesis
It is of note that although the drug can be prepared by the above route (cf e.g. thialbarbital
Thialbarbital (Intranarcon) is a barbiturate derivative invented in the 1960s. It has sedative effects, and was used primarily for induction in surgical anaesthesia. Thialbarbital is short acting and has less of a tendency to induce respiratory de ...
), reaction of barbital with phosphorus pentasulfide constitutes an alternative route to thiobarbital.
References
Thiobarbiturates GABAA receptor positive allosteric modulators {{nervous-system-drug-stub