Theca interna cells express
receptors for
luteinizing hormone
Luteinizing hormone (LH, also known as luteinising hormone, lutropin and sometimes lutrophin) is a hormone produced by gonadotropic cells in the anterior pituitary gland. The production of LH is regulated by gonadotropin-releasing hormone (G ...
(LH) to produce
androstenedione, which via a few steps, gives the
granulosa the precursor for
estrogen
Estrogen (also spelled oestrogen in British English; see spelling differences) is a category of sex hormone responsible for the development and regulation of the female reproductive system and secondary sex characteristics. There are three ...
manufacturing.
After rupture of the mature
ovarian follicle
An ovarian follicle is a roughly spheroid cellular aggregation set found in the ovaries. It secretes hormones that influence stages of the menstrual cycle. In humans, women have approximately 200,000 to 300,000 follicles at the time of puberty, ea ...
, the theca interna cells differentiate into the
theca lutein cells of the
corpus luteum
The corpus luteum (Latin for "yellow body"; : corpora lutea) is a temporary endocrine structure in female ovaries involved in the production of relatively high levels of progesterone, and moderate levels of estradiol, and inhibin A. It is the ...
. Theca lutein cells secrete
androgen
An androgen (from Greek ''andr-'', the stem of the word meaning ) is any natural or synthetic steroid hormone that regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors. This includes ...
s
[ and ]progesterone
Progesterone (; P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. It belongs to a group of steroid hormones called the progestogens and is the ma ...
. Theca lutein cells are also known as small luteal cells.[The IUPS Physiome Project --> Female Reproductive System - Cells]
Retrieved on Nov 9, 2009
See also
* theca folliculi
References
External links
*
* - "Mammal, canine ovary (LM, High)"
* - "Mammal, bovine ovary (LM, Medium)"
* - interna
*
Slide at trinity.edu
Endocrine system anatomy
Mammal female reproductive system
Steroid hormone secreting cells
Human female endocrine system
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