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The theca externa is the outer layer of the theca folliculi. It is derived from connective tissue, the cells resembling fibroblasts, and contains abundant collagen. During ovulation, the surge in luteinizing hormone increases cAMP which increases progesterone and
PGF2α PGF may refer to: * Paternal grandfather * Patterson–Gimlin film, purporting to show Bigfoot * IATA code of Perpignan–Rivesaltes Airport, France * Placental growth factor, a human gene * Vector graphics language in the PGF/TikZ pair * Precisi ...
production. The PGF2α induces the contraction of the
smooth muscle Smooth muscle is an involuntary non- striated muscle, so-called because it has no sarcomeres and therefore no striations (''bands'' or ''stripes''). It is divided into two subgroups, single-unit and multiunit smooth muscle. Within single-unit ...
cells of the theca externa, increasing intrafollicular pressure. This aids in rupture of the mature
oocyte An oocyte (, ), oöcyte, or ovocyte is a female gametocyte or germ cell involved in reproduction. In other words, it is an immature ovum, or egg cell. An oocyte is produced in a female fetus in the ovary during female gametogenesis. The femal ...
, or immature oocyte at the germinal vesicle stage in the canine, along with
plasmin Plasmin is an important enzyme () present in blood that degrades many blood plasma proteins, including fibrin clots. The degradation of fibrin is termed fibrinolysis. In humans, the plasmin protein (in the zymogen form of plasminogen) is encode ...
and collagenase degradation of the follicle wall.


References


External links

* * - "Mammal, canine ovary (LM, High)" * - "Mammal, bovine ovary (LM, Medium)" * - externa *
Slide at trinity.edu
Mammal female reproductive system {{genitourinary-stub