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Teething is the process by which an
infant In common terminology, a baby is the very young offspring of adult human beings, while infant (from the Latin word ''infans'', meaning 'baby' or 'child') is a formal or specialised synonym. The terms may also be used to refer to juveniles of ...
's first teeth (the
deciduous teeth Deciduous teeth or primary teeth, also informally known as baby teeth, milk teeth, or temporary teeth,Fehrenbach, MJ and Popowics, T. (2026). ''Illustrated Dental Embryology, Histology, and Anatomy'', 6th edition, Elsevier, page 287–296. are ...
, often called "baby teeth" or "milk teeth") appear by emerging through the gums, typically arriving in pairs. The mandibular central incisors are the first primary teeth to erupt, usually between 6 and 10 months of age and usually causes discomfort and pain to the infant. It can take several years for all 20 teeth to complete the
tooth eruption Tooth eruption is a process in tooth development in which the teeth enter the mouth and become visible. It is currently believed that the periodontal ligament plays an important role in tooth eruption. The first human teeth to appear, the decidu ...
. Though the process of teething is sometimes referred to as "cutting teeth", when teeth emerge through the gums they do not cut through the flesh. Instead,
hormones A hormone (from the Greek participle , "setting in motion") is a class of signaling molecules in multicellular organisms that are sent to distant organs or tissues by complex biological processes to regulate physiology and behavior. Hormones a ...
are released within the body that cause some cells in the gums to die and separate, allowing the teeth to come through. Teething may cause a slightly elevated temperature, but not rising into the
fever Fever or pyrexia in humans is a symptom of an anti-infection defense mechanism that appears with Human body temperature, body temperature exceeding the normal range caused by an increase in the body's temperature Human body temperature#Fever, s ...
range of greater than . Higher temperatures during teething are due to some form of infection, such as a herpes virus, initial infection of which is extremely widespread among children of teething age.


Signs and symptoms

The level of pain that a baby can handle will be different for each child. Some may appear to suffer more than others while they are teething. The soreness and swelling of the
gums The gums or gingiva (: gingivae) consist of the mucosal tissue that lies over the mandible and maxilla inside the mouth. Gum health and disease can have an effect on general health. Structure The gums are part of the soft tissue lining of the ...
before a tooth comes through is the cause of the pain and fussiness a baby experiences during this change. These symptoms usually begin about three to five days before the tooth shows, and they disappear as soon as the tooth breaks the skin. Some babies are not even bothered by teething. Common symptoms include
drooling Drooling, or slobbering, is the flow of saliva outside the mouth. Drooling can be caused by excess production of saliva, inability to retain saliva within the mouth (incontinence of saliva), or problems with swallowing (dysphagia or odynophagia) ...
or dribbling, increased
chew Chewing or mastication is the process by which food is crushed and ground by the teeth. It is the first step in the process of digestion, allowing a greater surface area for digestive enzymes to break down the foods. During the mastication proc ...
ing, mood changes, irritability or crankiness, and swollen gums. Crying,
sleeplessness Insomnia, also known as sleeplessness, is a sleep disorder where people have difficulty sleeping. They may have difficulty falling asleep, or staying asleep for as long as desired. Insomnia is typically followed by daytime sleepiness, low ene ...
, restless sleep at night, and mild fever are also associated with teething. Teething can begin as early as 3 months and continue until a child's third birthday. In rare cases, an area can be filled with fluid appearing over where a tooth is erupting and causing the gums to be even more sensitive. Pain is more often associated with the eruption of molars since they are larger, and do not penetrate through the gums as easily as the other teeth. Some noticeable symptoms that a baby has entered the teething stage include chewing on their fingers or toys to help relieve pressure on their gums. Babies might also refuse to eat or drink due to the pain. Symptoms will generally fade on their own, but a doctor should be notified if they worsen or are persistent. Teething may cause signs and symptoms in the mouth and gums, but does not cause problems elsewhere in the body. Pulling on the ears is another sign of pain: the pain in the mouth throbs throughout the baby's head, so they pull their ears believing that it will provide relief. Mild
rash A rash is a change of the skin that affects its color, appearance, or texture. A rash may be localized in one part of the body, or affect all the skin. Rashes may cause the skin to change color, itch, become warm, bumpy, chapped, dry, cracke ...
can develop around the mouth due to the skin irritation caused by excessive drooling or dribbling.


Sequence of appearance

The infant teeth tend to emerge in pairs – first one lower incisor emerges, then the other lower incisor, after which the next set begin to emerge. The general pattern of emergence is: # Lower central
incisor Incisors (from Latin ''incidere'', "to cut") are the front teeth present in most mammals. They are located in the premaxilla above and on the mandible below. Humans have a total of eight (two on each side, top and bottom). Opossums have 18, wher ...
s (2) at approximately 6 months # Upper central incisors (2) at approximately 8 months # Upper lateral incisors (2) at approximately 10 months # Lower lateral incisors (2) at approximately 10 months # First molars (4) at approximately 14 months # Canines (4) at approximately 18 months # Second molars (4) at approximately 2–3 years
Milk teeth Milk Teeth (often stylised as MILK TEETH) were a British punk rock band from Stroud, Gloucestershire, which formed in May 2013. The band officially announced their breakup on Facebook and Twitter on 4 September 2020. History Formation and earl ...
tend to emerge sooner in females than in males. The exact pattern and initial starting times of teething appear to be
hereditary Heredity, also called inheritance or biological inheritance, is the passing on of traits from parents to their offspring; either through asexual reproduction or sexual reproduction, the offspring cells or organisms acquire the genetic inform ...
. When and how teeth appear in an infant has no bearing on the health of the child.


Misdiagnosis as teething

Teething has not been shown to cause fever or diarrhea; however, the belief that teething causes fever is extremely common among parents. Whilst there is some evidence that teething can cause an elevated temperature, it does not cause
fever Fever or pyrexia in humans is a symptom of an anti-infection defense mechanism that appears with Human body temperature, body temperature exceeding the normal range caused by an increase in the body's temperature Human body temperature#Fever, s ...
(medically defined as rectal temperature greater than ). One small 1992 study found a significant rise in temperature on the day of eruption of the first tooth. Another study in 2000 found "mild temperature elevation" but not fever over . There is a risk that fever around the age of teething is dismissed as due to teething when it is actually due to illness, particularly infection by herpes viruses. "Coincidentally, primary tooth eruption begins at about the time that infants are losing maternal antibody protection against the herpes virus. Also, reports on teething difficulties have recorded symptoms which are remarkably consistent with primary oral herpetic infection, such as fever, irritability, sleeplessness, and difficulty with eating." "Younger infants with higher residual levels of antibodies would experience milder infections, and these would be more likely to go unrecognized or be dismissed as teething difficulty." Herpes virus infection may take the form of
primary herpetic gingivostomatitis Gingivostomatitis is a combination of gingivitis and stomatitis, or an inflammation of the oral mucosa and gingiva. Herpetic gingivostomatitis is often the initial presentation during the first ("primary") herpes simplex infection. It is of greate ...
(HSV-1) or of infection by
human herpesvirus 6 Human herpesvirus 6 (HHV-6) is the common collective name for human herpesvirus 6A (HHV-6A) and human herpesvirus 6B (HHV-6B). These closely related viruses are two of the nine known herpesviruses that have humans as their primary host. HHV-6 ...
(HHV-6), which infects 90% of children by age 2. "The symptoms of elevated temperature and facial rash could be explainable by infection with the HHV-6 agent, which is ubiquitous among infants of teething age." Other viruses may also cause fevers which might be misattributed to teething, but the oral involvement that may occur with herpes viruses makes misdiagnosis a particular risk for such infections.


Treatment

Infants may chew on objects to aid in the teething process. Teething necklaces or bracelets are not recommended as they can cause
choking Choking, also known as foreign body airway obstruction (FBAO), is a phenomenon that occurs when breathing is impeded by a blockage inside of the respiratory tract. An obstruction that prevents oxygen from entering the lungs results in oxygen de ...
,
strangulation Strangling or strangulation is compression of the neck that may lead to unconsciousness or death by causing an increasingly hypoxic state in the brain by restricting the flow of oxygen through the trachea. Fatal strangulation typically occurs ...
, or irritation of the mouth. Teething rings and other toys, called
teether A teether, teething toy, or chew toy is a device given to teething infants. It has the effect of reducing the pain of irritable wisdom teeth. Most modern teethers are silicone, but can also be made of wood or rubber. Some teethers are filled w ...
s, are often designed with textures. Some infants gain relief from chewing on cold objects. Some people freeze small chunks of fresh fruits or vegetables and put them in teething nets.


Medication

In cases where the infant is in obvious pain, some doctors recommend the use of
non-steroidal anti-inflammatory drug Non-steroidal anti-inflammatory drugs (NSAID) are members of a therapeutic drug class which reduces pain, decreases inflammation, decreases fever, and prevents blood clots. Side effects depend on the specific drug, its dose and duration of ...
s (NSAIDs) or child-safe pain-relief treatments containing
benzocaine Benzocaine, sold under the brand name Orajel amongst others, is a local anesthetic, belonging to the amino ester drug class, commonly used as a topical painkiller or in cough drops. It is the active ingredient in many over-the-counter ...
,
lidocaine Lidocaine, also known as lignocaine and sold under the brand name Xylocaine among others, is a local anesthetic of the amino amide type. It is also used to treat ventricular tachycardia and ventricular fibrillation. When used for local anae ...
, or choline salicylate. Benzocaine must be used cautiously because it can cause
methemoglobinemia Methemoglobinemia, or methaemoglobinaemia, is a condition of elevated methemoglobin in the blood. Symptoms may include headache, dizziness, shortness of breath, nausea, poor muscle coordination, and blue-colored skin (cyanosis). Complications ma ...
; choline salicylate is related to
aspirin Aspirin () is the genericized trademark for acetylsalicylic acid (ASA), a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain, fever, and inflammation, and as an antithrombotic. Specific inflammatory conditions that aspirin is ...
and "may cause
Reye's syndrome Reye syndrome is a rapidly worsening brain disease. Symptoms of Reye syndrome may include vomiting, personality changes, confusion, seizures, and loss of consciousness. While liver toxicity typically occurs in the syndrome, jaundice usually does ...
in susceptible children, especially those with or recovering from viral infections, or when used in combination with other NSAIDs". 5% lidocaine gel produces
anaesthesia Anesthesia (American English) or anaesthesia (British English) is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes. It may include some or all of analgesia (relief from or prev ...
(numbing) within 2–5 minutes, lasting for 10–20 minutes. However, one author concludes that, "Overall, the risks and adverse effects from inappropriate or prolonged use of pharmacological agents outweigh their potential benefits." She points out that "the psychological trauma involved in administering medications or applying topical preparations to infants must be considered", and argues that "the placebo effect must not be overlooked. For example, applying a gel of 20% benzocaine in
polyethylene glycol Polyethylene glycol (PEG; ) is a polyether compound derived from petroleum with many applications, from industrial manufacturing to medicine. PEG is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular wei ...
may give only a modest benefit over applying the placebo, which gives an efficacy of 60% compared with 90% for the active preparation." Medicines are often applied to the babies' gums to relieve swelling and pain. These gels are similar to the toothache gel that is used by adults for sore gums and toothaches, but is administered in much smaller doses. Teething gels work as a numbing agent to dull the nerves in the gums so that the pain is less noticeable. It is important to follow the directions on the package to ensure that the correct amount of medication is administered and that proper techniques are used to reduce the risk for infection. It is important not to let the medicine numb the throat as it may interfere with the normal gag reflex and may make it possible for food to enter the lungs. Similar medicines are also available in powder form, as "teething powder". Some traditional medicines used to treat teething pain have been found to be harmful due to high lead content, with effects including
toxic encephalopathy Toxic encephalopathy is a neurologic disorder caused by exposure to neurotoxic organic solvents such as toluene, following exposure to heavy metals such as manganese, as a side effect of melarsoprol treatment for African trypanosomiasis, adverse e ...
. Surma or
kohl Kohl may refer to: *Kohl (cosmetics), an ancient eye cosmetic *Kohl (surname), including a list of people with the surname *Kohl's Kohl's Corporation (Kohl's is stylized in all caps) is an American department store retail chain store, chain. ...
has traditionally been used in the Middle East and Indian subcontinent as a teething powder, as have the Middle Eastern saoott/cebagin. Santrinj – a 98%
lead oxide Lead oxides are a group of inorganic compounds with formulas including lead (Pb) and oxygen Oxygen is a chemical element; it has chemical symbol, symbol O and atomic number 8. It is a member of the chalcogen group (periodic table), gr ...
product otherwise used as a paint primer – is also used in the Middle East as a home remedy for teething.


History

Teething used to be considered (wrongly) a cause of death, as many children died in the first years of life, at the same time as teething occurs. "The tendency in the past to attribute serious disease to teething was so prevalent that in 1842 teething was the registered cause of death in 4.8% of all infants who died in London under the age of 1 year and 7.3% of those between the ages of 1 to 3 years according to the Registrar General's report." Ironically, while teething is a natural process which creates little more than discomfort, some methods for relieving teething pain have caused serious harm and even death. Old remedies for teething include "blistering, bleeding, placing leeches on the gums, and applying cautery to the back of the head". In the sixteenth century the French surgeon
Ambroise Paré Ambroise Paré (; – 20 December 1590) was a French barber surgeon who served in that role for kings Henry II, Francis II, Charles IX and Henry III. He is considered one of the fathers of surgery and modern forensic pathology and a pione ...
introduced the lancing of gums using a lancet, in the belief that teeth were failing to emerge from the gums due to lack of a pathway, and that this failure was a cause of death. This belief and practice persisted for centuries, with some exceptions, until towards the end of the nineteenth century lancing became increasingly controversial and was then abandoned, although as late as 1938 an Anglo-American dental textbook advised in favour of lancing, and described the procedure. In the first half of the twentieth century, teething powders in the English-speaking world often contained
calomel Calomel is a Mercury element, mercury chloride mineral with Chemical formula, formula Hg2Cl2 (see mercury(I) chloride). It was used as a medicine from the 16th to early 20th century, despite frequently causing mercury poisoning in patients. The ...
, a form of mercury. It was removed from most powders in 1954 when it was shown to cause "pink disease" ( acrodynia), a form of
mercury poisoning Mercury poisoning is a type of metal poisoning due to exposure to mercury. Symptoms depend upon the type, dose, method, and duration of exposure. They may include muscle weakness, poor coordination, numbness in the hands and feet, skin rashe ...
. Teething toys have a long history. In England in the 17th–19th centuries, a ''coral'' meant a teething toy made of coral, ivory, or bone, often mounted in silver as the handle of a rattle. A museum curator has suggested that these substances were used as
sympathetic magic Sympathetic magic, also known as imitative magic, is a type of Magic (paranormal), magic based on imitation or correspondence. Similarity and contagion James George Frazer coined the term "sympathetic magic" in ''The Golden Bough'' (1889); Rich ...
, and that the animal bone could symbolize animal strength to help the child cope with pain.


See also

*
Tooth eruption Tooth eruption is a process in tooth development in which the teeth enter the mouth and become visible. It is currently believed that the periodontal ligament plays an important role in tooth eruption. The first human teeth to appear, the decidu ...
*
Deciduous teeth Deciduous teeth or primary teeth, also informally known as baby teeth, milk teeth, or temporary teeth,Fehrenbach, MJ and Popowics, T. (2026). ''Illustrated Dental Embryology, Histology, and Anatomy'', 6th edition, Elsevier, page 287–296. are ...
*
Permanent teeth Permanent teeth or adult teeth are the second set of teeth formed in diphyodont mammals. In humans and old world simians, there are thirty-two permanent teeth, consisting of six maxillary and six mandibular molars, four maxillary and four mandib ...
*
Dentition Dentition pertains to the development of teeth and their arrangement in the mouth. In particular, it is the characteristic arrangement, kind, and number of teeth in a given species at a given age. That is, the number, type, and morpho-physiology ...


References


External links


NHS Choices Birth to Five Planner
Teething
NHS Choices Health A–Z
Teething * {{Infants and their care Infancy Pediatrics Teeth Pedodontology