The Translational Genomics Research Institute (TGen) is a

non-profit A nonprofit organization (NPO), also known as a nonbusiness entity, nonprofit institution, not-for-profit organization, or simply a nonprofit, is a non-governmental (private) legal entity organized and operated for a collective, public, or so ...

genomics Genomics is an interdisciplinary field of molecular biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, ...

research institute A research institute, research centre, or research organization is an establishment founded for doing research. Research institutes may specialize in basic research or may be oriented to applied research. Although the term often implies natural ...

based in Phoenix, Arizona, United States.

History and activities

TGen was established in July 2002 by Jeffrey Trent in

Phoenix, Arizona Phoenix ( ) is the List of capitals in the United States, capital and List of cities and towns in Arizona#List of cities and towns, most populous city of the U.S. state of Arizona. With over 1.6 million residents at the 2020 census, it is the ...

, with an initial investment of US$100 million from Arizona public- and private-sector investors. The field of translational genomics research searches for ways to apply results from the

Human Genome Project The Human Genome Project (HGP) was an international scientific research project with the goal of determining the base pairs that make up human DNA, and of identifying, mapping and sequencing all of the genes of the human genome from both a ...

to the development of improved diagnostics,

prognostics Prognostics is an engineering discipline focused on predicting the time at which a system or a component will no longer perform its intended function. This lack of performance is most often a failure beyond which the system can no longer be used to ...

, and therapies for cancer,

neurological disorders Neurological disorders represent a complex array of medical conditions that fundamentally disrupt the functioning of the nervous system. These Disorder of consciousness, disorders affect the brain, spinal cord, and nerve networks, presenting unique ...

diabetes Diabetes mellitus, commonly known as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels. Diabetes is due to either the pancreas not producing enough of the hormone insulin, or the cells of th ...

and other complex

disease A disease is a particular abnormal condition that adversely affects the structure or function (biology), function of all or part of an organism and is not immediately due to any external injury. Diseases are often known to be medical condi ...

s. The mission of TGen is to make and translate genomic discoveries into advances in human health. TGen has contributed to the growth of scientific research and biotechnology in Arizona. The institute has been involved in collaborations and studies, such as the research on chronic traumatic encephalopathy (CTE) in former NFL players in partnership with Exosome Sciences.

References

{{authority control Genetics or genomics research institutions Bioinformatics organizations Research institutes in Arizona Research institutes established in 2002 Organizations based in Arizona 2002 establishments in Arizona