Tensin-like C1 domain-containing phosphatase is an
enzyme
An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...
that in humans is encoded by the ''TENC1''
gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
.
The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in regulating cell migration. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.
Interactions
TENC1 has been shown to
interact with
AXL receptor tyrosine kinase
Tyrosine-protein kinase receptor UFO is a protein that in human is encoded by the ''AXL'' gene. The gene was initially designated as UFO, in allusion to the unidentified function of this protein. However, in the years since its discovery, researc ...
.
References
Further reading
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External links
PDBe-KBprovides an overview of all the structure information available in the PDB for Human Tensin-2
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