Synthetic ribosomes are artificial small-molecules that can synthesize peptides in a sequence-specific matter. David Alan Leigh's lab built synthetic ribosome using a chemical structure based on a

rotaxane In chemistry, a rotaxane () is a mechanically interlocked molecular architecture consisting of a dumbbell-shaped molecule which is threaded through a macrocycle (see graphical representation). The two components of a rotaxane are kinetically ...

. The Cédric Orelle research group created ribosomes with tethered and inseparable subunits (or Ribo-T).

References

{{Reflist Synthetic biology