Also known as Queensland itch, seasonal recurrent dermatitis (SSRD), summer itch or more technically, ''Culicoides'' hypersensitivity.
Sweet itch is a medical condition in
equines
''Equus'' , is a genus of mammals in the family Equidae, which includes horses, donkeys, and zebras. Within the Equidae, ''Equus'' is the only recognized extant genus, comprising seven living species. Like Equidae more broadly, ''Equus'' has n ...
caused by an
allergic
Allergies, also known as allergic diseases, refer a number of conditions caused by the hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic derm ...
response to the bites of ''
Culicoides
''Culicoides'' is a genus of biting midges in the family Ceratopogonidae. There are over 1000 species in the genus,Connelly, C. RBiting midges: ''Culicoides'' spp.Featured Creatures, Entomology and Nematology Department, University of Florida IFA ...
''
midge
A midge is any small fly, including species in several families of non- mosquito Nematoceran Diptera. Midges are found (seasonally or otherwise) on practically every land area outside permanently arid deserts and the frigid zones. Some m ...
s. It may be found in horses and
ponies
A pony is a type of small horse ('' Equus ferus caballus''). Depending on the context, a pony may be a horse that is under an approximate or exact height at the withers, or a small horse with a specific conformation and temperament. Compared ...
, especially in the warmer regions. It may also occur, too, in other equines. It is also found in Canada, Australia, the US and many other parts of the world.
Causes
A
hypersensitivity
Hypersensitivity (also called hypersensitivity reaction or intolerance) refers to undesirable reactions produced by the normal immune system, including allergies and autoimmunity. They are usually referred to as an over-reaction of the immune ...
reaction to specific
allergen
An allergen is a type of antigen that produces an abnormally vigorous immune response in which the immune system fights off a perceived threat that would otherwise be harmless to the body. Such reactions are called allergies.
In technical ter ...
s (
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respon ...
molecules causing an extreme immune response in sensitised individuals) in the
saliva of ''Culicoides'' midges. There are multiple allergens involved, although some works claim that the larger proteins (of molecular weight 65
kDa
The dalton or unified atomic mass unit (symbols: Da or u) is a non-SI unit of mass widely used in physics and chemistry. It is defined as of the mass of an unbound neutral atom of carbon-12 in its nuclear and electronic ground state and at re ...
) are the most important. These allergens appear to be cross-reactive across many species of ''Culicoides'' - i.e. many different varieties of midges produce similar allergens, giving the same effects upon horses.
The hypersensitivity response is mediated by
IgE, an
antibody
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and Viral disease, viruses. The antibody recognizes a unique m ...
produced by the horse's
immune system
The immune system is a network of biological processes that protects an organism from diseases. It detects and responds to a wide variety of pathogens, from viruses to parasitic worms, as well as Tumor immunology, cancer cells and objects such ...
which binds the allergens, causing a cascade production of
histamine
Histamine is an organic nitrogenous compound involved in local immune responses, as well as regulating physiological functions in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus. Since histamine was discovered in ...
and
cytokines which make the horse's skin inflamed and
itchy. Of these, histamine appears the most important in the initial phase of reaction.
Symptoms
* The allergic reaction develops at the site where the insects feed
* The majority of affected horses show skin lesions affecting the
mane
Mane may refer to:
* Mane (horse), the line of hair along the spine of the neck
* Mane (lion), the hair found around the male mammal's neck
In arts and entertainment
* ''Mane'' (film) is a 1990 Kannada language film directed by Girish Kasaravall ...
and tail and dorsal midline.
*
Ventral
Standard anatomical terms of location are used to unambiguously describe the anatomy of animals, including humans. The terms, typically derived from Latin or Greek roots, describe something in its standard anatomical position. This position prov ...
midline symptoms may also occur.
* Lesions around the ears and head are also common.
* These lesions are characterised by intense
pruritus
Itch (also known as pruritus) is a sensation that causes the desire or reflex to scratch. Itch has resisted many attempts to be classified as any one type of sensory experience. Itch has many similarities to pain, and while both are unpleasant ...
(itching), which results in rubbing and considerable self-trauma. This damage is caused by the horse violently rubbing itself against objects, and causes:
** broken hairs
** broken and sometimes bleeding skin
** bald patches.
*
Secondary infections may result
Treatment and prevention
Few treatments are fully efficacious once lesions have appeared. The only effective form of treatment is preventative - i.e. prevent further insect bites - so these techniques will also be discussed here. Treatments generally fall into one of the following categories:
*Insecticides and repellents: These may be applied to the horse or its environment. The most commonly used and effective are
permethrin
Permethrin is a medication and an insecticide. As a medication, it is used to treat scabies and lice. It is applied to the skin as a cream or lotion. As an insecticide, it can be sprayed onto clothing or mosquito nets to kill the insects tha ...
s. and
benzyl benzoate Citronella has been used, with variable effect. Some sources advocate draining of any stagnant water or pools, to reduce the local breeding potential of the insects. Midge numbers are often larger near water sources, for example ponds, bogs, and slow moving water. Moving the horse away from these areas may help to prevent further problems.
*Barrier techniques: Rugs etc., that prevent flies and midges settling on the animal's skin to bite. These include "Boett Rugs" and fly masks. In addition, thin screens may be placed over stable doors and windows to exclude biting insects. Stabling the horse at times of day when the midges are most prevalent is also quite effective.
*Immunotherapy: A wide variety
immunotherapy
Immunotherapy or biological therapy is the treatment of disease by activating or suppressing the immune system. Immunotherapies designed to elicit or amplify an immune response are classified as ''activation immunotherapies,'' while immunotherap ...
and
desensitisation protocols have been trialled in attempts to reduce or modify the immune response, with considerable success rates. More research is ongoing, and first products are already marketed.
*Nutritional supplements: Various supplements may be effective in individuals, including
fatty acid
In chemistry, particularly in biochemistry, a fatty acid is a carboxylic acid with an aliphatic chain, which is either saturated or unsaturated. Most naturally occurring fatty acids have an unbranched chain of an even number of carbon atoms, ...
supplementation and
linseed oil
Linseed oil, also known as flaxseed oil or flax oil (in its edible form), is a colourless to yellowish oil obtained from the dried, ripened seeds of the flax plant (''Linum usitatissimum''). The oil is obtained by Expeller pressing, pressing, some ...
. However, although owners perceived an improvement, this was not bourne out by objective statistical analysis.
*Symptomatic control: Control of symptoms to some degree can be achieved with
antihistamines
Antihistamines are drugs which treat allergic rhinitis, common cold, influenza, and other allergies. Typically, people take antihistamines as an inexpensive, generic (not patented) drug that can be bought without a prescription and provides ...
(especially
hydroxyzine
Hydroxyzine, sold under the brand names Atarax, Vistaril and others, is an antihistamine medication. It is used in the treatment of itchiness, insomnia, anxiety, and nausea, including that due to motion sickness. It is used either by mouth or ...
, and with
corticosteroids
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are in ...
, although the potential side effects (e.g.
laminitis
Laminitis is a disease that affects the feet of ungulates and is found mostly in horses and cattle. Clinical signs include foot tenderness progressing to inability to walk, increased digital pulses, and increased temperature in the hooves. Seve ...
, immune suppression) make this a less preferred option. In addition,
antibiotics
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention ...
may be required to manage any
secondary infection
An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable di ...
.
*Alternative medicines: A wide variety of
herbal
A herbal is a book containing the names and descriptions of plants, usually with information on their medicinal, tonic, culinary, toxic, hallucinatory, aromatic, or magical powers, and the legends associated with them.Arber, p. 14. A herbal ...
,
homeopathic
Homeopathy or homoeopathy is a pseudoscientific system of alternative medicine. It was conceived in 1796 by the German physician Samuel Hahnemann. Its practitioners, called homeopaths, believe that a substance that causes symptoms of a dis ...
and other alternative remedies have been suggested. Among the natural remedies suggested are
sulfur
Sulfur (or sulphur in British English) is a chemical element with the symbol S and atomic number 16. It is abundant, multivalent and nonmetallic. Under normal conditions, sulfur atoms form cyclic octatomic molecules with a chemical formul ...
, wild
geranium
''Geranium'' is a genus of 422 species of annual, biennial, and perennial plants that are commonly known as geraniums or cranesbills. They are found throughout the temperate regions of the world and the mountains of the tropics, but mostly i ...
(as the base for a shampoo),
lavender oil
Lavender oil is an essential oil obtained by distillation from the flower spikes of certain species of lavender. There are over 400 types of lavender worldwide with different scents and qualities. Two forms of lavender oil are distinguished, ''l ...
,
aloe vera
''Aloe vera'' () is a succulent plant species of the genus ''Aloe''. It is widely distributed, and is considered an invasive species in many world regions.
An evergreen perennial, it originates from the Arabian Peninsula, but grows wild in tro ...
(to reduce the itching).
The Holistic Horse
/ref>
Overall, the wide variety of treatments proposed leads to the conclusion that no one method is universally effective.
See also
*Ceratopogonidae
Ceratopogonidae is a family of flies commonly known as no-see-ums, or biting midges, generally in length. The family includes more than 5,000 species, distributed worldwide, apart from the Antarctic and the Arctic.
Ceratopogonidae are holomet ...
(The family of which ''Culicoides'' is a member)
*'' Culicoides imicola'' (species of midge)
*'' Culicoides impunctatus'' (species of midge)
* Veterinary parasitology
References
{{Reflist
* PonyGalax
Detailed Information On SSRD
External links
British Horse Society Sweet Itch Datasheet
Detailed Information on Sweet Itch and its Causes
Information about what Sweet Itch is, Causes and Treatment
The Sweet Itch Help Centre
Horse diseases