Suranjith Seneviratne
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Suranjith Seneviratne is a doctor from
Sri Lanka Sri Lanka, officially the Democratic Socialist Republic of Sri Lanka, also known historically as Ceylon, is an island country in South Asia. It lies in the Indian Ocean, southwest of the Bay of Bengal, separated from the Indian subcontinent, ...
who practices in
allergology Allergies, also known as allergic diseases, are various conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include Allergic rhinitis, hay fever, Food allergy, food al ...
and
immunology Immunology is a branch of biology and medicine that covers the study of Immune system, immune systems in all Organism, organisms. Immunology charts, measures, and contextualizes the Physiology, physiological functioning of the immune system in ...
.


Education

Seneviratne completed his basic Medical Degree with First Class Honours, eight distinctions and ten gold medals and was his year's valedictorian. He earned his Medical Degree in Internal Medicine and attended
John Radcliffe Hospital John Radcliffe Hospital (informally known as the JR or the John Radcliffe) is a large tertiary teaching hospital in Oxford, England. It forms part of Oxford University Hospitals NHS Foundation Trust and is named after John Radcliffe (physician) ...
in
Oxford Oxford () is a City status in the United Kingdom, cathedral city and non-metropolitan district in Oxfordshire, England, of which it is the county town. The city is home to the University of Oxford, the List of oldest universities in continuou ...
for training in Clinical Immunology and Allergy. He completed a DPhil in Molecular Immunology and Allergy at the Weatherall Institute of Molecular Medicine,
University of Oxford The University of Oxford is a collegiate university, collegiate research university in Oxford, England. There is evidence of teaching as early as 1096, making it the oldest university in the English-speaking world and the List of oldest un ...
as a Commonwealth Scholar.


Professional activity

Currently a Consultant in Clinical Immunology and Allergy at the Royal Free Hospital and University College London, the largest Primary Immunodeficiency Centre in Europe, Seneviratne was a Consultant and Lead Clinician in Clinical Immunology and Allergy at St Mary's Hospital and
Imperial College London Imperial College London, also known as Imperial, is a Public university, public research university in London, England. Its history began with Prince Albert of Saxe-Coburg and Gotha, Prince Albert, husband of Queen Victoria, who envisioned a Al ...
before, a world renowned Allergy and Immunology Centre, and the birthplace of the widely practiced procedure of Allergen Immunotherapy over 100 years ago. Seneviratne has also been appointed as the Director of Centre for Mast Cell Disorders and as the President of the UK-Sri Lanka Immunology Foundation, an organisation that contributes towards the Immunology and Allergy education in
Sri Lanka Sri Lanka, officially the Democratic Socialist Republic of Sri Lanka, also known historically as Ceylon, is an island country in South Asia. It lies in the Indian Ocean, southwest of the Bay of Bengal, separated from the Indian subcontinent, ...
. He is one of the leading authorities in the world on the diagnosis and management of Histamine and Mast Cell related disorders and has managed Mast Cell/ Histamine/ Immunology/ Allergy aspects of over 1100 patients with
Ehlers Danlos Syndrome Ehlers may refer to: * Ehlers–Danlos syndrome Ehlers–Danlos syndromes (EDS) is a group of 14 genetic connective-tissue disorders. Symptoms often include loose joints, joint pain, stretchy velvety skin, and abnormal scar formation. These ...
in both the UK and Asia during the past 7 years.


Publications

Seneviratne is the author of over 134 journal publications and was one of the principal investigators in the Pan-European study of adult Food Allergy (EUROPREVALL) in the UK. Furthermore, he has been an author of research articles published in high impact journals such as ''
Nature Medicine ''Nature Medicine'' is a monthly peer-reviewed medical journal published by Nature Portfolio covering all aspects of medicine. It was established in 1995. The journal seeks to publish research papers that "demonstrate novel insight into disease p ...
'', ''Journal of Experimental Medicine'', ''Blood'', ''
The Journal of Allergy and Clinical Immunology ''The Journal of Allergy and Clinical Immunology'' (JACI) is a monthly peer-reviewed medical journal covering research on allergy and immunology. It is one of three official journals of the American Academy of Allergy, Asthma, and Immunology. The j ...
'' and the ''Journal of Clinical Investigation and Allergy''. He is currently the Principal Investigator of the STILLPAD-UK study, a prospective study of lung disease in Immunodeficiency. He directs the Gastrointestinal Immunology and Cancer Research Group at the Department of Surgery, Faculty of Medicine at the
University of Colombo The University of Colombo (informally Colombo University or UoC) is a Public University, public research university located primarily in Colombo, Sri Lanka. It is the oldest institution of modern higher education in Sri Lanka. Specialised in t ...
,
Sri Lanka Sri Lanka, officially the Democratic Socialist Republic of Sri Lanka, also known historically as Ceylon, is an island country in South Asia. It lies in the Indian Ocean, southwest of the Bay of Bengal, separated from the Indian subcontinent, ...
and is a member of the
NIHR The National Institute for Health and Care Research (NIHR) is the British government's major funder of clinical, public health, social care and translational research. With a budget of over £1.2 billion in 2020–21, its mission is to "improv ...
Bio-resource Genetic study on Primary Immunodeficiency patients Seneviratne is also involved in several molecular genetic studies on patients with
Hyper IgM syndrome Hyper IgM syndrome is a rare primary immune deficiency disorders characterized by low or absent levels of serum IgG, IgA, IgE and normal or increased levels of serum IgM. They are resulting from mutations in the pathway from B-cell activation ...
, LRBA deficiency, CTLA4 Haploinsufficiency, Hyper IgE syndrome, CVID, Complement deficiencies, Food Allergy and Mast Cell Activation Disorder. In addition Seneviratne has also contributed/involved in the following publications: * Respiratory Infections and Antibiotic Usage in Common Variable Immunodeficiency * Epidemiology, Pathogenesis and Treatment of Ulcerative Colitis in South Asia * Crohn's disease in South Asia * Mast cell disorders in Ehlers-Danlos syndrome * Mini-review: Can non-human leucocyte antigen genes determine susceptibility to severe dengue syndromes?


Affiliations

Professor Seneviratne is a member of a following organisations: * Royal College of Physicians * Royal College of Pathologists * Ceylon College of Physicians * British Society of Immunology * British Society of Allergy and Clinical Immunology * European Academy of Allergy and Clinical Immunology * American Academy of Allergy and Clinical Immunology * Clinical Immunology Society * European Society of Immunodeficiency


Known for

* Food Allergy * Urticia * Mast cell or Histamine disorders * Low lymphocyte counts or low immunoglobulin G, A or M level * Inflammatory conditions – involving several systems ** Vasculitis ** SLE ** Other Autoimmune disorders * Drug Allergy * Angioedema * Allergic Rhinitis and de-sensitisation * Suspected Immunodeficiency disorders * Allergic Asthma * Evaluation of a patient's immune factors * Recurrent chest or sinus infections


References

{{DEFAULTSORT:Seneviratne, Suranjith Year of birth missing (living people) Living people Sinhalese people Sri Lankan medical doctors Allergologists Immunologists