Subramania Ranganathan
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Subramania Ranganathan (1934–2016), popularly known as Ranga, was an Indian bioorganic chemist and professor and head of the department of chemistry at the Indian Institute of Technology, Kanpur. He was known for his studies on synthetic and mechanistic organic chemistry and was an elected fellow
Indian National Science Academy The Indian National Science Academy (INSA) is a national academy in New Delhi New Delhi (; ) is the Capital city, capital of India and a part of the Delhi, National Capital Territory of Delhi (NCT). New Delhi is the seat of all three b ...
, National Academy of Sciences, India and the
Indian Academy of Sciences The Indian Academy of Sciences, Bangalore was founded by Indian Physicist and List of Nobel laureates, Nobel Laureate Chandrasekhara Venkata Raman, C. V. Raman, and was registered as a society on 27 April 1934. Inaugurated on 31 July 1934, it ...
The
Council of Scientific and Industrial Research The Council of Scientific and Industrial Research (CSIR; IAST: ''vaigyanik tathā audyogik anusandhāna pariṣada'') is a research and development (R&D) organisation in India to promote scientific, industrial and economic growth. Headquarter ...
, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 1977, for his contributions to chemical sciences.


Biography

Ranganathan, born on 2 February 1934 in the south Indian state of
Tamil Nadu Tamil Nadu (; , TN) is the southernmost States and union territories of India, state of India. The List of states and union territories of India by area, tenth largest Indian state by area and the List of states and union territories of Indi ...
, graduated in chemistry from
Madras University The University of Madras is a public university, public State university (India), state university in Chennai (Madras), Tamil Nadu, India. Established in 1857, it is one of the oldest and most prominent universities in India, incorporated by an ...
and continued there to complete his master's degree in 1957. Before moving to US to pursue his doctoral studies on a Sloan Kettering Foundation fellowship, he worked at the biochemistry department of the
Central Leather Research Institute Central Leather Research Institute or CLRI is the world's largest leather research institute in terms of Academic paper, research papers and patents. The institute located in Chennai, Tamil Nadu was founded on 24 April 1948 as a constituent labo ...
for a short while. In the US, he enrolled at
Ohio State University The Ohio State University (Ohio State or OSU) is a public university, public Land-grant university, land-grant research university in Columbus, Ohio, United States. A member of the University System of Ohio, it was founded in 1870. It is one ...
at Harold Shechter's laboratory and secured a PhD in 1962. He moved to the laboratory of
Robert Burns Woodward Robert Burns Woodward (April 10, 1917 – July 8, 1979) was an American organic chemist. He is considered by many to be the preeminent synthetic organic chemist of the twentieth century, having made many key contributions to the subject, esp ...
, the 1965
Nobel laureate The Nobel Prizes (, ) are awarded annually by the Royal Swedish Academy of Sciences, the Swedish Academy, the Karolinska Institutet, and the Norwegian Nobel Committee to individuals and organizations who make outstanding contributions in th ...
, at
Harvard University Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyma ...
for his post- doctoral studies and in 1964, he shifted to Woodward Research Institute,
Basel Basel ( ; ), also known as Basle ( ), ; ; ; . is a city in northwestern Switzerland on the river Rhine (at the transition from the High Rhine, High to the Upper Rhine). Basel is Switzerland's List of cities in Switzerland, third-most-populo ...
to complete the studies in 1964. On his return to India in 1966, he joined
IIT Kanpur The Indian Institute of Technology Kanpur (IIT- Kanpur or IIT-K) is a public institute of technology located in Kanpur, Uttar Pradesh, India. As an Indian Institute of Technology (IIT), it was declared an Institute of National Importance by th ...
where he spent his entire official academic career, holding positions of a professor, head of the department and dean, before superannuating in 1994. Post-retirement, he served as an INSA senior scientist, first at National Institute for Interdisciplinary Science and Technology and later at the
Indian Institute of Chemical Technology The CSIR-Indian Institute of Chemical Technology is a national-level research center located in Hyderabad, Telangana, India under the Council of Scientific and Industrial Research (CSIR). IICT conducts research in basic and applied chemistry, bio ...
(IICT), both the facilities were earlier known as Regional Research Laboratories. Ranganathan was holding the position of an honorary position at IICT when he died on 8 January 2016, at the age of 81, survived by his son, Anand. He was married to Darshan Ranganathan, an academic, research associate and his co-author; his wife predeceased him. Anand Ranganathan is a scientist working on drugs for TB and Malaria at
International Centre for Genetic Engineering and Biotechnology The International Centre for Genetic Engineering and Biotechnology (ICGEB) was established as a project of the United Nations Industrial Development Organization (UNIDO) in 1983. The Organisation has three Component laboratories with over 45 ongo ...
.


Legacy

During his post-doctoral days, Ranganathan worked closely with Woodward and was known to have assisted the latter in his work on
Woodward–Hoffmann rules The Woodward–Hoffmann rules (or the pericyclic selection rules) are a set of rules devised by Robert Burns Woodward and Roald Hoffmann to rationalize or predict certain aspects of the stereochemistry and activation energy of Pericyclic reaction, ...
. It was during this time, he accomplished the total synthesis of
Cephalosporin C Cephalosporin C is an antibiotic of the cephalosporin class. It was isolated from a fungus of the genus '' Acremonium'' and first characterized in 1961. Although not a very active antibiotic itself, synthetic analogs of cephalosporin C, such as ...
and Woodward's Nobel lecture was based on this synthesis. Later, basing his researches on synthetic and mechanistic organic chemistry, he identified new methodologies for the synthesis of
prostaglandins Prostaglandins (PG) are a group of physiologically active lipid compounds called eicosanoids that have diverse hormone-like effects in animals. Prostaglandins have been found in almost every tissue in humans and other animals. They are derive ...
, a group of biologically active compounds. His researches have been documented by way of a number of books and over 200 peer-reviewed articles; the online repository of Indian Academy of Sciences has listed 97 of them; and many authors have cited his researches in their publications.


Awards and honors

Ranganathan received the Basudev Banerjee Medal in 1975 and the Council of Scientific and Industrial Research awarded him the
Shanti Swarup Bhatnagar Prize Shanti or Shanthi may refer to: In Sanskrit * Inner peace, a state of being mentally and spiritually at peace, with enough knowledge and understanding to keep oneself strong in the face of discord or stress * Kshanti, one of the paramitas of B ...
, one of the highest Indian science awards, in 1977. He received R. C. Mehrotra Endowment Gold Medal in 2000 and the Silver Medal of the
Chemical Research Society of India Chemical Research Society of India (CRSI) is an India based scientific society dedicated to the field of chemistry. It was established in 1999 as a part of celebrating India's 50th anniversary of independence Independence is a conditi ...
in 2001; CRSI would honor him again in 2006 with the Lifetime Achievement Award. In 2014, he was awarded the Best Teacher Award by the Indian National Science Academy. He held lectureships of the University Grants Commission of India (1979–80), Science and Engineering Research Board (1991) and
Department of Atomic Energy The Department of Atomic Energy (DAE) (IAST: ''Paramāṇu Ūrjā Vibhāga'') is an Indian government department with headquarters in Mumbai, Maharashtra, India. DAE was established in 1954 with Jawaharlal Nehru as its first minister and Homi ...
(2001) and delivered several award orations including Professor K. Venkatraman Lecture (1979), Professor A. B. Kulkarni Lecture (1982); Professor N. V. Subba Rao Memorial Lecture (1985), Professor T. R. Seshadri Memorial Lecturer (1993) and Maitreyi Memorial Lecture (1994). The
Indian Academy of Sciences The Indian Academy of Sciences, Bangalore was founded by Indian Physicist and List of Nobel laureates, Nobel Laureate Chandrasekhara Venkata Raman, C. V. Raman, and was registered as a society on 27 April 1934. Inaugurated on 31 July 1934, it ...
elected him as a fellow in 1975 and he became an elected fellow of and the
Indian National Science Academy The Indian National Science Academy (INSA) is a national academy in New Delhi New Delhi (; ) is the Capital city, capital of India and a part of the Delhi, National Capital Territory of Delhi (NCT). New Delhi is the seat of all three b ...
and the National Academy of Sciences, India in 1981 and 1991 respectively.


Books

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See also


References

{{DEFAULTSORT:Ranganathan, Subramania Recipients of the Shanti Swarup Bhatnagar Award in Chemical Science 1934 births Fellows of the Indian Academy of Sciences Tamil scientists University of Madras alumni 2016 deaths Scientists from Tamil Nadu Fellows of the Indian National Science Academy Fellows of the National Academy of Sciences, India Ohio State University alumni Harvard University alumni Academic staff of IIT Kanpur Council of Scientific and Industrial Research Indian Tamil academics Indian organic chemists 20th-century Indian chemists