IgA pemphigus is a subtype of
pemphigus with two distinct forms:
* ''Subcorneal pustular dermatosis'' (also known as Sneddon–Wilkinson disease and pustulosis subcornealis) is skin condition that is a rare, chronic, recurrent, pustular eruption characterized histopathologically by subcorneal pustules that contain abundant neutrophils.
[James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. .] This is distinct from and not to be confused with
subcorneal pustular dermatosis type of IgA pemphigus
IgA pemphigus is a subtype of pemphigus with two distinct forms:
* ''Subcorneal pustular dermatosis'' (also known as Sneddon–Wilkinson disease and pustulosis subcornealis) is skin condition that is a rare, chronic, recurrent, pustular eruption ...
.
Sneddon's syndrome, also known as Ehrmann-Sneddon syndrome, is also a different syndrome.
* ''Intraepidermal neutrophilic IgA dermatosis'' is characterized
histologically by
intraepidermal bullae with
neutrophils
Neutrophils (also known as neutrocytes or heterophils) are the most abundant type of granulocytes and make up 40% to 70% of all white blood cells in humans. They form an essential part of the innate immune system, with their functions varying in ...
, some
eosinophils, and
acantholysis.
History
Early descriptions were made by
Darrell Wilkinson, a British dermatologist.
See also
*
Pemphigus
*
List of cutaneous conditions
Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands. The major function of this system is as a barrier against t ...
*
List of conditions caused by problems with junctional proteins
*
List of immunofluorescence findings for autoimmune bullous conditions
References
External links
Chronic blistering cutaneous conditions
{{Vesiculobullous disease