Tetrachlorvinphos is an
organophosphate
In organic chemistry, organophosphates (also known as phosphate esters, or OPEs) are a class of organophosphorus compounds with the general structure , a central phosphate molecule with alkyl or aromatic substituents. They can be considered ...
insecticide
Insecticides are pesticides used to kill insects. They include ovicides and larvicides used against insect eggs and larvae, respectively. The major use of insecticides is in agriculture, but they are also used in home and garden settings, i ...
used to kill
flea
Flea, the common name for the order (biology), order Siphonaptera, includes 2,500 species of small flightless insects that live as external parasites of mammals and birds. Fleas live by hematophagy, ingesting the blood of their hosts. Adult f ...
s and
tick
Ticks are parasitic arachnids of the order Ixodida. They are part of the mite superorder Parasitiformes. Adult ticks are approximately 3 to 5 mm in length depending on age, sex, and species, but can become larger when engorged. Ticks a ...
s.
[
]
History
Tetrachlorvinphos was initially registered for use in the United States in 1966 by the U.S. Department of Agriculture
The United States Department of Agriculture (USDA) is an executive department of the United States federal government that aims to meet the needs of commercial farming and livestock food production, promotes agricultural trade and production ...
. Tetrachlorvinphos was originally registered for use on various food crops, livestock, pet animals, and in or around buildings. The crop uses were voluntarily canceled from product registrations in 1987. In 2014, the Natural Resources Defense Council
The Natural Resources Defense Council (NRDC) is a United States–based 501(c)(3) non-profit international environmental advocacy group, with its headquarters in New York City and offices in Washington, D.C., San Francisco, Los Angeles, Chicag ...
(NRDC) filed a lawsuit against the United States Environmental Protection Agency
The Environmental Protection Agency (EPA) is an independent agency of the United States government tasked with environmental protection matters. President Richard Nixon proposed the establishment of EPA on July 9, 1970; it began operation on De ...
(EPA) seeking EPA to respond to NRDC's 2009 petition to ban tetrachlorvinphos in common pet flea treatment products.
Human health hazards
Symptoms of exposure to this material include increased perspiration
Perspiration, also known as sweat, is the fluid secreted by sweat glands in the skin of mammals.
Two types of sweat glands can be found in humans: eccrine glands and Apocrine sweat gland, apocrine glands. The eccrine sweat glands are distribu ...
, nausea
Nausea is a diffuse sensation of unease and discomfort, sometimes perceived as an urge to vomit. It can be a debilitating symptom if prolonged and has been described as placing discomfort on the chest, abdomen, or back of the throat.
Over 30 d ...
, lachrymation
Tears are a clear liquid secreted by the lacrimal glands (tear gland) found in the eyes of all land mammals. Tears are made up of water, electrolytes, proteins, lipids, and mucins that form layers on the surface of eyes. The different types of ...
, salivation
Saliva (commonly referred as spit or drool) is an extracellular fluid produced and secreted by salivary glands in the mouth. In humans, saliva is around 99% water, plus electrolytes, mucus, white blood cells, epithelial cells (from which DN ...
, blurred vision, diarrhea
Diarrhea (American English), also spelled diarrhoea or diarrhœa (British English), is the condition of having at least three loose, liquid, or watery bowel movements in a day. It often lasts for a few days and can result in dehydration d ...
, pulmonary edema
Pulmonary edema (British English: oedema), also known as pulmonary congestion, is excessive fluid accumulation in the tissue or air spaces (usually alveoli) of the lungs. This leads to impaired gas exchange, most often leading to shortness ...
, respiratory embarrassment and convulsion
A convulsion is a medical condition where the body muscles contract and relax rapidly and repeatedly, resulting in uncontrolled shaking. Because epileptic seizures typically include convulsions, the term ''convulsion'' is often used as a synony ...
s. The chemical material may be absorbed through the skin and is a lachrymator. It is a cholinesterase inhibitor
Cholinesterase inhibitors (ChEIs), also known as anti-cholinesterase, are chemicals that prevent the breakdown of the neurotransmitter acetylcholine or butyrylcholine by cholinesterase. This increases the amount of the acetylcholine or butyryl ...
and is a positive animal carcinogen
A carcinogen () is any agent that promotes the development of cancer. Carcinogens can include synthetic chemicals, naturally occurring substances, physical agents such as ionizing and non-ionizing radiation, and biologic agents such as viruse ...
.
Chemical properties
The substance is insoluble in water. Flash point
The flash point of a material is the "lowest liquid temperature at which, under certain standardized conditions, a liquid gives off vapours in a quantity such as to be capable of forming an ignitable vapour/air mixture".
The flash point is somet ...
data are not available for this chemical; however, it is probably combustible. Tetrachlorvinphos is slowly hydrolyzed in neutral and aqueous acidic media. Is rapidly hydrolyzed in alkaline media.
Alternative Chemical Names
This is a listing of alternate names for this chemical, including trade names and synonyms.
References
''This article contains public domain text from the EPA and the NOAA ''.
External links
Tetrachlorvinphos (TCVP)
Environmental Protection Agency
Environmental Protection Agency may refer to the following government organizations:
* Environmental Protection Agency (Queensland), Australia
* Environmental Protection Agency (Ghana)
* Environmental Protection Agency (Ireland)
* Environmenta ...
{{Acetylcholine metabolism and transport modulators
Acetylcholinesterase inhibitors
Organophosphate insecticides
Chloroarenes
IARC Group 2B carcinogens
Methoxy compounds