Steven Krilis (born 26 November 1947, in
Athens
Athens ( ; el, Αθήνα, Athína ; grc, Ἀθῆναι, Athênai (pl.) ) is both the capital and largest city of Greece. With a population close to four million, it is also the seventh largest city in the European Union. Athens dominates ...
,
Greece
Greece,, or , romanized: ', officially the Hellenic Republic, is a country in Southeast Europe. It is situated on the southern tip of the Balkans, and is located at the crossroads of Europe, Asia, and Africa. Greece shares land borders with ...
) is Professor of Immunology Allergies and Infectious diseases at the
University of New South Wales
The University of New South Wales (UNSW), also known as UNSW Sydney, is a public research university based in Sydney, New South Wales, Australia. It is one of the founding members of Group of Eight, a coalition of Australian research-intensive ...
and
St George Hospital in
Sydney
Sydney ( ) is the capital city of the state of New South Wales, and the most populous city in both Australia and Oceania. Located on Australia's east coast, the metropolis surrounds Sydney Harbour and extends about towards the Blue Mountain ...
, Australia. He is a
Fellow of the Royal Australasian College of Physicians
Fellow of the Royal Australasian College of Physicians, abbreviated as the post-nominal initials FRACP, is a recognition of the completion of the prescribed postgraduate specialist training programme in internal adult or internal paediatric medicin ...
.
Krilis specializes in the treatment and research of
Antiphospholipid syndrome; his laboratory was the first to recognise the major auto-antigen involved. In 2004, after a decade of research, Krilis led a team of researchers which identified a mechanism that can cause blood clots – a discovery with implications for those susceptible to deep-vein thrombosis, strokes, recurrent miscarriages and Antiphospholipid syndrome.
Krillis was made a
Member of the Order of Australia
The Order of Australia is an honour that recognises Australian citizens and other persons for outstanding achievement and service. It was established on 14 February 1975 by Elizabeth II, Queen of Australia, on the advice of the Australian Gove ...
(AM) in the
2019 Queen's Birthday Honours in recognition of his "significant service to medical research in the areas of inflammation, thrombosis and allergic disease".
Publications
Among his over 120 peer-reviewed papers, the most cited are:
*McNeil, H.P., Simpson, R.J., Chesterman, C.N., Krilis, S.A."Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: β2-glycoprotein I (apolipoprotein H)" (1990)
, 87 (11), pp. 4120–4124. Cited 920 times.
*McNeil, H.P., Chesterman, C.N., Krilis, S.A. "Immunology and clinical importance of antiphospholipid antibodies" (1991)
Advances in Immunology, 49, pp. 193–280. Cited 284 times.
*Hunt, J., Krilis, S. "The fifth domain of β2-glycoprotein I contains a phospholipid binding site (Cys281-Cys288) and a region recognized by anticardiolipin antibodies" (1994)
Journal of Immunology, 152 (2), pp. 653–659. Cited 195 times.
*Hunt, J.E., McNeil, H.P., Morgan, G.J., Crameri, R.M., Krilis, S.A. "A phospholipid-beta 2-glycoprotein I complex is an antigen for anticardiolipin antibodies occurring in autoimmune disease but not with infection." (1992)
Lupus
Lupus, technically known as systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. Symptoms vary among people and may be mild to severe. Comm ...
1 (2), pp. 75–81. Cited 147 times.
*Miyakis, S., Lockshin, M.D., Atsumi, T., Branch, D.W., Brey, R.L., Cervera, R., Derkesen, R.H.W.M., De Groot, P.G., Koike, T., Meroni, P.L., Reber, G., Shoenfeld, Y., Tincani, A., Vlachoyiannopoulos, P.G., Krilis, S.A. "International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)" (2006)
Journal of Thrombosis and Haemostasis 4 (2), pp. 295–306. Cited 116 times.
*Hunt, J.E., Simpson, R.J., Krilis, S.A. "Identification of a region of β2-glycoprotein I critical for lipid binding and anti-cardiolipin antibody cofactor activity" (1993)
90 (6), pp. 2141–2145. Cited 111 times.
References
External links
UNSW Position detailsan
research interests
{{DEFAULTSORT:Krilis, Steven
1947 births
Living people
University of New South Wales Medical School alumni
Members of the Order of Australia