Steven M. Block (born 1952) is an American biophysicist and Professor at
Stanford University with a joint appointment in the departments of Biology and Applied Physics. In addition, he is a member of the scientific advisory group
JASON
Jason ( ; ) was an ancient Greece, ancient Greek Greek mythology, mythological hero and leader of the Argonauts, whose quest for the Golden Fleece featured in Greek literature. He was the son of Aeson, the rightful king of Iolcos. He was marri ...
, a senior fellow of Stanford's
Freeman Spogli Institute for International Studies
Stanford University has many centers and institutes dedicated to the study of various specific topics. These centers and institutes may be within a department, within a school but across departments, an independent laboratory, institute or center ...
, and an amateur
bluegrass musician. Block received his B.A. and M.A. from
Oxford University
Oxford () is a city in England. It is the county town and only city of Oxfordshire. In 2020, its population was estimated at 151,584. It is north-west of London, south-east of Birmingham and north-east of Bristol. The city is home to the ...
. He has been elected to the U.S.
National Academy of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nat ...
(2007) and the
American Academy of Arts and Sciences
The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, ...
(2000), and is a winner of the
Max Delbruck Prize
The Max Delbruck Prize, formerly known as the Biological physics prize, is awarded by the Division of Biological Physics of the American Physical Society, to recognize and encourage outstanding achievement in biological physics research. The pr ...
of the
American Physical Society (2008), as well as the Single Molecule Biophysics Prize of the
Biophysical Society
The Biophysical Society is an international scientific society whose purpose is to lead the development and dissemination of knowledge in biophysics. Founded in 1958, the Society currently consists of over 7,500 members in academia, government, an ...
(2007). He served as President of the Biophysical Society during 2005-6. His graduate work was completed in the laboratory of
Howard Berg
Howard Curtis Berg (March 16, 1934 – December 30, 2021) was the Herchel Smith Professor of Physics and Professor of Molecular and Cellular Biology at Harvard University, where he taught biophysics and studied the motility of the bacterium ''Esch ...
at the
University of Colorado
The University of Colorado (CU) is a system of public universities in Colorado. It consists of four institutions: University of Colorado Boulder, University of Colorado Colorado Springs, University of Colorado Denver, and the University o ...
and
Caltech
The California Institute of Technology (branded as Caltech or CIT)The university itself only spells its short form as "Caltech"; the institution considers other spellings such a"Cal Tech" and "CalTech" incorrect. The institute is also occasional ...
. He received his Ph.D. in 1983 and went on to do postdoctoral research at Stanford. Since that time, Block has held positions at the
Rowland Institute for Science
The Rowland Institute for Science was founded by Edwin H. Land, founder of Polaroid Corporation, as a nonprofit, privately endowed basic research organization in 1980. The institute merged with Harvard University on July 1, 2002, and is now called ...
,
Harvard University
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of high ...
, and
Princeton University
Princeton University is a private research university in Princeton, New Jersey. Founded in 1746 in Elizabeth as the College of New Jersey, Princeton is the fourth-oldest institution of higher education in the United States and one of the n ...
before returning to Stanford in 1999.
As a graduate student, Block picked apart the
adaptation kinetics
Kinetics ( grc, κίνησις, , kinesis, ''movement'' or ''to move'') may refer to:
Science and medicine
* Kinetics (physics), the study of motion and its causes
** Rigid body kinetics, the study of the motion of rigid bodies
* Chemical k ...
involved in bacterial
chemotaxis. As an independent scientist, Block has pioneered the use of
optical tweezers
Optical tweezers (originally called single-beam gradient force trap) are scientific instruments that use a highly focused laser beam to hold and move microscopic and sub-microscopic objects like atoms, nanoparticles and droplets, in a manner simila ...
, a technique developed by
Arthur Ashkin
Arthur Ashkin (September 2, 1922 – September 21, 2020) was an American scientist and Nobel laureate who worked at Bell Laboratories and Lucent Technologies. Ashkin has been considered by many as the father of optical tweezers, "LaserFest – th ...
, to study biological enzymes and polymers at the single-molecule level. Work in his lab has led to the direct observation of the 8 nm steps taken by
kinesin
A kinesin is a protein belonging to a class of motor proteins found in eukaryotic cells.
Kinesins move along microtubule (MT) filaments and are powered by the hydrolysis of adenosine triphosphate (ATP) (thus kinesins are ATPases, a type of enz ...
and the sub-nanometer stepping motions of
RNA polymerase
In molecular biology, RNA polymerase (abbreviated RNAP or RNApol), or more specifically DNA-directed/dependent RNA polymerase (DdRP), is an enzyme that synthesizes RNA from a DNA template.
Using the enzyme helicase, RNAP locally opens the ...
on a
DNA template. While consulting for the United States government through
JASON
Jason ( ; ) was an ancient Greece, ancient Greek Greek mythology, mythological hero and leader of the Argonauts, whose quest for the Golden Fleece featured in Greek literature. He was the son of Aeson, the rightful king of Iolcos. He was marri ...
, Block has researched the many threats associated with bioterrorism and headed influential studies on how advances in genetic engineering have impacted biological warfare.
Selected publications
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*
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*
*
References
External links
Steven Block ProfileBlock Lab Website
{{DEFAULTSORT:Block, Steven
1952 births
Living people
University of Colorado alumni
Harvard University faculty
Princeton University faculty
Stanford University Department of Biology faculty
Stanford University Department of Applied Physics faculty
Members of the United States National Academy of Sciences
Members of JASON (advisory group)
Alumni of the University of Oxford
Fellows of the American Academy of Arts and Sciences
Presidents of the Biophysical Society
Fellows of the American Physical Society