Stephanie Schorge is a Professor of Neuroscience in the Department of Neuroscience, Physiology and Pharmacology at

University College London University College London (Trade name, branded as UCL) is a Public university, public research university in London, England. It is a Member institutions of the University of London, member institution of the Federal university, federal Uni ...

. She is known for her research into mutations that cause neurological diseases.

Education and career

Schorge received her B.S. from

Yale University Yale University is a Private university, private Ivy League research university in New Haven, Connecticut, United States. Founded in 1701, Yale is the List of Colonial Colleges, third-oldest institution of higher education in the United Stat ...

in 1994. She obtained a Ph.D. in Neuroscience from

Brown University Brown University is a Private university, private Ivy League research university in Providence, Rhode Island, United States. It is the List of colonial colleges, seventh-oldest institution of higher education in the US, founded in 1764 as the ' ...

where she worked with Diane Lipscombe. Schorge has held postdoctoral positions at the Department of Pharmacology and the Institute of Neurology, both at the University College London. She has had a fellowship from the

Worshipful Company of Pewterers The Worshipful Company of Pewterers is one of the 111 Livery Companies of the City of London. It ranks 16th in the order of precedence of City Livery Companies and has existed since at least 1348. Like all the other City Livery Companies, the ...

and a university research fellowship from the

Royal Society The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, re ...

. In 2018 Schorge moved to the

UCL School of Pharmacy The UCL School of Pharmacy (formerly The School of Pharmacy, University of London) is the pharmacy school of University College London (UCL). The School forms part of UCL's Faculty of Life Sciences and is located in London, United Kingdom. Th ...

to become professor in translational neuroscience and director of the research department of pharmacology. In 2021 she became head of the Department of Neuroscience, Physiology and Pharmacology (NPP). She was subsequently awarded the

Sophia Jex-Blake Sophia Louisa Jex-Blake (21 January 1840 – 7 January 1912) was an English physician, teacher, and feminism, feminist. She led the campaign to secure women access to a university education, when she began studying medicine at the Universit ...

Chair of

Physiology Physiology (; ) is the science, scientific study of function (biology), functions and mechanism (biology), mechanisms in a life, living system. As a branches of science, subdiscipline of biology, physiology focuses on how organisms, organ syst ...

Research

Schorge is known for her research in how mutations in ion channels can cause neurological disease and how manipulating ion channels can be used to treat disease. She has worked on RNA processing in voltage gated calcium channels, single channel biophysics of

NMDA receptor The ''N''-methyl-D-aspartate receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and predominantly Ca2+ ion channel found in neurons. The NMDA receptor is one of three types of ionotropic glutamate receptors, the other ...

s. and investigated the functional impacts of mutations in ion channels that are linked to human neurological disorders, the

channelopathies Channelopathies are a group of diseases caused by the dysfunction of ion channel subunits or their interacting proteins. These diseases can be inherited or acquired by other disorders, drugs, or toxins. Mutations in genes encoding ion channels, wh ...

. She has also examined the genetics and functions of mutations linked to epilepsy, particularly in sodium channels, and researched gene therapy treatments for epilepsy.

Selected publications

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References

External links

* {{DEFAULTSORT:Schorge, Stephanie Living people Yale University alumni Brown University alumni Academics of University College London Women neuroscientists Year of birth missing (living people)