United States
* Spencer House (Hartford, Connecticut), listed on the National Register of Historic Places (NRHP) in Hartford County * Spencer House in Columbus, Georgia, former home of educator William Henry Spencer * Spencer House (Lima, New York), listed on the NRHP in Livingston County * Spencer House (Syracuse, New York), listed on the NRHP in Onondaga County * Arthur Champlin Spencer and Margaret Fenton Spencer House, Portland, Oregon, listed on the NRHP in Multnomah County * Spencer–Shippee–Lillbridge House, East Greenwich, Rhode Island, listed on the NRHP in Kent County * William B. Spencer House, West Warwick, Rhode Island, listed on the NRHP in Kent County * Spencer House (Bishopville, South Carolina), listed on the NRHP in Lee County * Spencer House (Cincinnati), a hotel from 1853 to 1935 {{disambiguation