(), abbreviated OPC, is a

pharmaceutical company The pharmaceutical industry is a Medicine, medical industry that discovers, develops, produces, and markets pharmaceutical goods such as medications and medical devices. Medications are then administered to (or Self-medicate, self-administered b ...

headquartered in

Tokyo Tokyo, officially the Tokyo Metropolis, is the capital of Japan, capital and List of cities in Japan, most populous city in Japan. With a population of over 14 million in the city proper in 2023, it is List of largest cities, one of the most ...

Osaka is a Cities designated by government ordinance of Japan, designated city in the Kansai region of Honshu in Japan. It is the capital of and most populous city in Osaka Prefecture, and the List of cities in Japan, third-most populous city in J ...

and

Naruto ''Naruto'' is a Japanese manga series written and illustrated by Masashi Kishimoto. It tells the story of Naruto Uzumaki, a young ninja who seeks recognition from his peers and dreams of becoming the Hokage, the leader of his village. T ...

Japan Japan is an island country in East Asia. Located in the Pacific Ocean off the northeast coast of the Asia, Asian mainland, it is bordered on the west by the Sea of Japan and extends from the Sea of Okhotsk in the north to the East China Sea ...

. The company was established August 10, 1964.

History

OPC's parent company Otsuka Holdings Co. Ltd. joined the

Tokyo Stock Exchange The , abbreviated as Tosho () or TSE/TYO, is a stock exchange located in Tokyo, Japan. The exchange is owned by Japan Exchange Group (JPX), a holding company that it also lists (), and operated by Tokyo Stock Exchange, Inc., a wholly owned sub ...

through an

initial public offering An initial public offering (IPO) or stock launch is a public offering in which shares of a company are sold to institutional investors and usually also to retail (individual) investors. An IPO is typically underwritten by one or more investm ...

(IPO) on December 15, 2010, at which time Otsuka Holdings was Japan's No.2 drug maker by sales after industry leader

Takeda Pharmaceutical Company The is a Japanese multinational pharmaceutical company. It is the third largest pharmaceutical company in Asia, behind Sinopharm and Shanghai Pharmaceuticals, and one of the top 20 largest pharmaceutical companies in the world by revenue (t ...

. The IPO debuted at $2.4 billion, making it the largest for a pharmaceutical company up to that time.

Otsuka Pharmaceutical Co. Ltd Holdings

In 1955, the company started a

football Football is a family of team sports that involve, to varying degrees, kick (football), kicking a football (ball), ball to score a goal (sports), goal. Unqualified, football (word), the word ''football'' generally means the form of football t ...

club called "Otsuka Pharmaceutical SC." In 2005 the name changed to

Tokushima Vortis is a Japanese professional football club located in Tokushima, capital of Tokushima Prefecture. The club currently playing in the J2 League, the Japanese second tier of professional football league. Name origin The name, "Vortis" was named in 19 ...

. The club is based in Naruto. In 2008, Otsuka Pharmaceutical Co. acquired 49% of Alma S.A., which is the parent company of CG Roxane. In early 2012, Otsuka announced it would focus its "future operations on CNS disorders and oncology". This decision necessitated a revision in the terms of an agreement with UCB to end collaboration on immunology products while continuing collaboration in the CNS area. In March 2017, the company agreed to acquire Neurovance, Inc. for $250 million, gaining the firm's Phase III-ready

ADHD Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterised by symptoms of inattention, hyperactivity, impulsivity, and emotional dysregulation that are excessive and pervasive, impairing in multiple ...

drug centanafadine (previously EB-1020). Otsuka's subsidiary Otsuka America will pay $100 million upfront for Neurovance, plus up-to $150 million in development and approval milestones. As a result of the transaction, Neurovance will operate as an indirect, wholly owned subsidiary. In 2023, the company announced the acquisition of Mindset Pharma for $58.6 million.

Acquisition history

* Otsuka Pharmaceutical Co., Ltd **

Ridge Vineyards Ridge Vineyards is a California winery specializing in Cabernet Sauvignon, Zinfandel, and Chardonnay wines. Ridge produces wine at two winery locations in northern California. The original winery facilities are located at an elevation of on Mo ...

(Acq 1986) **

Crystal Geyser Water Company Crystal Geyser Water Company, or just Crystal Geyser, is a private company founded in 1977 in Calistoga, California which produces bottled sparkling water based on mineral water and spring water sources at their original facility in Calistoga. C ...

(Acq 1990) **

Astex Pharmaceuticals Astex Pharmaceuticals is a biotechnology company focused on the discovery and development of drugs in oncology and diseases of the central nervous system. Astex was founded in 1999 by Sir Tom Blundell, Chris Abell & Harren Jhoti, and is located ...

(Merged 2011, Acq 2013) *** Astex Therapeutics Limited *** SuperGen, Inc ** Avanir Pharmaceuticals (Acq 2014) **

Daiya Daiya Foods Inc. is a Canada-based dairy- alternative food company located in Burnaby, British Columbia. The company was established in 2008 by Andre Kroecher and Greg Blake. Daiya's original products are cheese analogues made from coconut oil a ...

(Acq 2017) ** ReCor Medical, Inc. (Acq 2019) ** Otsuka America, Inc *** Visterra (Acq 2019) *** Neurovance, Inc (Acq 2017) *** Mindset Pharma Inc (Acq 2023) *** Jnana Therapeutics Inc. (Acq 2024)

Products

CalorieMate CalorieMate (カロリーメイト ''karorīmeito'') is a brand of nutritional energy bar and energy gel foods produced by Otsuka Pharmaceutical Co., in Japan. It was first released in 1983 debuting with a cheese flavored block. CalorieMate com ...

Pocari Sweat is a Japanese sports drink, manufactured by Otsuka Pharmaceutical. It was launched in 1980, and is sold across Asia and the Middle East; it is also available in Australia, Mexico and the United States. Pocari Sweat is a mild-tasting, non-carbo ...

Oronamin C , produced by Otsuka Chemical Holdings Co., Ltd., (distributed and sold by Otsuka Pharmaceutical Co.) is a carbonated beverage available in Japan. It is commonly called Oronamin C or Oronamin. Its name is similar to the Takeda Pharmaceutical Co. ...

* Aripiprazole / Abilify * Brexpiprazole / Rexulti *

Rejoyn Rejoyn is a prescription-only digital therapeutic smartphone app approved by the US FDA for the treatment of major depressive disorder (MDD) in adults ages 22 and up. It is prescribed in conjunction with standard antidepressant medication and profe ...

* SoyJoy

References

External links

*
Otsuka Pharmaceutical Company, Limited.
*
Otsuka Integrated Report 2017
(PDF) () {{Authority control Companies listed on the Tokyo Stock Exchange Pharmaceutical companies established in 1964 Japanese brands 2010 initial public offerings Multinational companies headquartered in Japan Naruto, Tokushima