Smita Krishnaswamy is an American scientist and associate professor in genetics and computer science at

Yale University Yale University is a Private university, private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the List of Colonial Colleges, third-oldest institution of higher education in the United Sta ...

. She specializes in the development of

machine learning Machine learning (ML) is a field of inquiry devoted to understanding and building methods that 'learn', that is, methods that leverage data to improve performance on some set of tasks. It is seen as a part of artificial intelligence. Machine ...

techniques to analyze high-dimensional high-throughput biomedical data with applications in

immunology Immunology is a branch of medicineImmunology for Medical Students, Roderick Nairn, Matthew Helbert, Mosby, 2007 and biology that covers the medical study of immune systems in humans, animals, plants and sapient species. In such we can see ther ...

immunotherapy Immunotherapy or biological therapy is the treatment of disease by activating or suppressing the immune system. Immunotherapies designed to elicit or amplify an immune response are classified as ''activation immunotherapies,'' while immunotherap ...

cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bl ...

neuroscience Neuroscience is the science, scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions and disorders. It is a Multidisciplinary approach, multidisciplinary science that combines physiology, an ...

developmental biology Developmental biology is the study of the process by which animals and plants grow and develop. Developmental biology also encompasses the biology of regeneration, asexual reproduction, metamorphosis, and the growth and differentiation of ste ...

and health outcomes. She organized the Open Problems in Single-Cell Biology effort with the

Chan Zuckerberg Initiative The Chan Zuckerberg Initiative (CZI) is an organization established and owned by Facebook founder Mark Zuckerberg and his wife Priscilla Chan with an investment of 99 percent of the couple's wealth from their Facebook shares over their lifetime ...

and remains a scientific advisor for the project.

Education and early career

Krishnaswamy obtained her Ph.D. in computer science and engineering from

University of Michigan , mottoeng = "Arts, Knowledge, Truth" , former_names = Catholepistemiad, or University of Michigania (1817–1821) , budget = $10.3 billion (2021) , endowment = $17 billion (2021)As o ...

in 2008. She then joined IBM's T.J. Watson Research Center as a scientist in the systems division, where she researched formal methods for automated error detection. Her Deltasyn algorithm was utilized in

IBM System p The IBM System p is a high-end line of RISC ( Power)/UNIX-based servers. It was the successor of the RS/6000 line, and predecessor of the IBM Power Systems server series. History The previous RS/6000 line was originally a line of workstations ...

and

IBM System z IBM Z is a family name used by IBM for all of its z/Architecture mainframe computers. In July 2017, with another generation of products, the official family was changed to IBM Z from IBM z Systems; the IBM Z family now includes the newest mod ...

high-performance server chips. Krishnaswamy switched her research efforts to biology and completed postdoctoral training in 2015 at

Columbia University Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manha ...

in the Department of

Systems Biology Systems biology is the computational modeling, computational and mathematical analysis and modeling of complex biological systems. It is a biology-based interdisciplinary field of study that focuses on complex interactions within biological syst ...

, where she focused on learning computational models of

cellular signaling In biology, cell signaling (cell signalling in British English) or cell communication is the ability of a cell to receive, process, and transmit signals with its environment and with itself. Cell signaling is a fundamental property of all cellula ...

from single-cell

mass cytometry Mass cytometry is a mass spectrometry technique based on inductively coupled plasma mass spectrometry and time of flight mass spectrometry used for the determination of the properties of cells (cytometry). In this approach, antibodies are conjug ...

data.

Awards and honors

In 2022, Krishnaswamy's research, teaching and community work were honored by a

FASEB Excellence in Science Award The Excellence in Science Award was established by the Federation of American Societies for Experimental Biology (FASEB) in 1989 to recognize outstanding achievement by women in biological science. All women who are members of one or more of the so ...

(Early-Career Investigator Award) from the Federation of American Societies for Experimental Biology funded by Eli Lilly and Company. In 2009, Krishnaswamy was the recipient of the European Design Automation Association's Outstanding Dissertation Award in the category "new directions in circuit and system test". In 2005, Krishnaswamy received a best-paper award from the

Design Automation and Test in Europe A design is a plan or specification for the construction of an object or system or for the implementation of an activity or process or the result of that plan or specification in the form of a prototype, product, or process. The verb ''to design' ...

conference for the paper of which she was the lead author.

Publications

Krishnaswamy co-authored a book published by

Springer Verlag Springer Science+Business Media, commonly known as Springer, is a German multinational publishing company of books, e-books and peer-reviewed journals in science, humanities, technical and medical (STM) publishing. Originally founded in 1842 in ...

and over 50 peer-reviewed publications, including journal papers in ''

Nature Biotechnology ''Nature Biotechnology'' is a monthly peer-reviewed scientific journal published by Nature Portfolio. The chief editor heads an in-house team of editors. The focus of the journal is biotechnology including research results and the commercial busi ...

'', ''

Nature Protocols ''Nature Protocols'', published by the Nature Publishing Group, is an on-line scientific journal publishing methods in a recipe-style format. The journal was launched in June 2006 and the content includes both classical methods and cutting-edge tec ...

'',

Nature Methods ''Nature Methods'' is a monthly peer-reviewed scientific journal covering new scientific techniques. It was established in 2004 and is published by Springer Nature under the Nature Portfolio. Like other ''Nature'' journals, there is no external ed ...

Science Science is a systematic endeavor that Scientific method, builds and organizes knowledge in the form of Testability, testable explanations and predictions about the universe. Science may be as old as the human species, and some of the earli ...

'', ''

Cell Cell most often refers to: * Cell (biology), the functional basic unit of life Cell may also refer to: Locations * Monastic cell, a small room, hut, or cave in which a religious recluse lives, alternatively the small precursor of a monastery w ...

'' and conference papers in

International Conference on Machine Learning The International Conference on Machine Learning (ICML) is the leading international academic conference in machine learning. Along with NeurIPS and ICLR, it is one of the three primary conferences of high impact in machine learning and artifici ...

.
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References

External links

Open Problems in Single-Cell Biology
* * {{DEFAULTSORT:Krishnaswamy, Smita Living people American women scientists Yale School of Medicine faculty American electrical engineers University of Michigan alumni IBM employees People from Kalamazoo, Michigan Year of birth missing (living people)