Slayton A. Evans Jr. (May 17, 1943 – March 24, 2001) was an American chemist and professor at the
University of North Carolina, Chapel Hill. He was a leading researcher into organophosphorus chemistry. His research led to a greater understanding of the functions of
organophosphate
In organic chemistry, organophosphates (also known as phosphate esters, or OPEs) are a class of organophosphorus compounds with the general structure , a central phosphate molecule with alkyl or aromatic substituents. They can be considered a ...
compounds and innovations in methods to produce chemical compounds for pharmaceutical drugs.
Early life and education
Slayton Alvin Evans Jr. was born on May 17, 1943, in Chicago, Illinois to Corine M. Thompson Evans and Slayton A. Evans, Sr.
Months later, his father was called to serve in
World War II.
When Slayton was three years old, the family moved to
Meridian, Mississippi
Meridian is the List of municipalities in Mississippi, seventh largest city in the U.S. state of Mississippi, with a population of 41,148 at the 2010 United States Census, 2010 census and an estimated population in 2018 of 36,347. It is the count ...
,
where they lived in a segregated
public housing project and his father worked at a
J. C. Penney
Penney OpCo LLC, doing business as JCPenney and often abbreviated JCP, is a midscale American department store chain operating 667 stores across 49 U.S. states and Puerto Rico. Departments inside JCPenney stores include Mens, Womens, Boys, Girl ...
store. Slayton's interest in chemistry began early, when he was given a chemistry set. In addition, a small microscope allowed him to study various plant specimens and insects. Evans and his two younger siblings enrolled at a
segregated primary school run by the
Roman Catholic Church, and later he attended St. Joseph's High School. In 1957, when Evans was in the ninth grade, news of the artificial satellite
Sputnik
Sputnik 1 (; see § Etymology) was the first artificial Earth satellite. It was launched into an elliptical low Earth orbit by the Soviet Union on 4 October 1957 as part of the Soviet space program. It sent a radio signal back to Earth for t ...
inspired him to learn about rocketry and attempt to build his own. While he was given permission by the nuns at his school to buy chemicals to make
rocket fuel, he had to make his own powdered charcoal. He built six rockets, two of them achieving liftoff.
Evans helped pay for his school tuition by mowing lawns and during eighth grade he was a junior assistant janitor at his elementary school. Later he worked in the high school cafeteria. In his third year of high school, he considered going into the
Air Force, but was too tall for flight training. However, he took several competitive examinations and was the recipient of an academic scholarship to
Tougaloo College where he also received an athletic scholarship for basketball. He enrolled at Tougaloo in 1961.
By the end of his first year, Evans had top marks in chemistry in his class. He got a summer job working for the pharmaceutical company
Abbott Laboratories
Abbott Laboratories is an American multinational medical devices and health care company with headquarters in Abbott Park, Illinois, United States. The company was founded by Chicago physician Wallace Calvin Abbott in 1888 to formulate known dr ...
in Chicago where he was tasked first with creating chemical compounds from raw materials, and later with identifying the stages of chemical reactions.
Evans graduated from Tougaloo with a Bachelor of Science in Chemistry in 1965.
Evans was encouraged to attend graduate school, though he didn't know how to pay for it. He briefly attended the
Illinois Institute of Technology before transferring to
Case Western Reserve University
Case Western Reserve University (CWRU) is a private research university in Cleveland, Ohio. Case Western Reserve was established in 1967, when Western Reserve University, founded in 1826 and named for its location in the Connecticut Western Reser ...
in Cleveland, Ohio, where he was offered a research assistant position in the chemistry department. In his first year, he received a draft notice to go to the
Vietnam War. University officials contacted the draft board and explained that Evans' research was crucial to the war effort. He was researching a medicine to treat
schistosomiasis
Schistosomiasis, also known as snail fever, bilharzia, and Katayama fever, is a disease caused by parasitic flatworms called schistosomes. The urinary tract or the intestines may be infected. Symptoms include abdominal pain, diarrhea, bloody s ...
, a disease caused by parasitic flatworms that are common in Southeast Asia. He completed his coursework in 1969 and received his Ph.D in Chemistry in early 1970.
Research and academic career
Evans took a postdoctoral fellowship at the
University of Texas at Arlington for the 1970–1971 academic year, followed by second fellowship at the
University of Notre Dame in Indiana,
where he worked with the organic chemist
Ernest L. Eliel studying
stereochemistry
Stereochemistry, a subdiscipline of chemistry, involves the study of the relative spatial arrangement of atoms that form the structure of molecules and their manipulation. The study of stereochemistry focuses on the relationships between stereois ...
.
Upon the completion of the fellowship, he was invited to be a research instructor at
Dartmouth College in 1972,
though they did not have the laboratory equipment he required to continue his research.
Evans then joined the faculty of the
University of North Carolina at Chapel Hill as an Assistant Professor of Chemistry in 1974.
He was the first African-American chemistry professor at the university.
After 10 years at Chapel Hill, Evans became a full professor, and in 1992 was honored with a Kenan Professor chair.
Evans was a leading researcher in the field of organophosphorus chemistry,
authoring more than 85 scientific articles on organosulfur and organophosphorus chemistry.
His research led to a deeper understanding of the functions of
organophosphate
In organic chemistry, organophosphates (also known as phosphate esters, or OPEs) are a class of organophosphorus compounds with the general structure , a central phosphate molecule with alkyl or aromatic substituents. They can be considered a ...
compounds and innovations in methods to produce chemical compounds for pharmaceutical drugs. Evans was inspired by
William Standish Knowles, who in 1968 developed a method of
asymmetric hydrogenation, which Evans used to develop alternative
asymmetric synthesis
Enantioselective synthesis, also called asymmetric synthesis, is a form of chemical synthesis. It is defined by IUPAC as "a chemical reaction (or reaction sequence) in which one or more new elements of chirality are formed in a substrate molecul ...
methods as a way to produce single
stereoisomers. Evans started experimenting with organophosphorus chemistry in 1970, developing a process using phosphorus atoms of organophosphate compounds as agents to produce specific stereoisomers. He also devised a method of asymmetric synthesis to synthesize alpha-amino phosphonic acids by adding phosphorus to
sulfimide
In chemistry, a sulfilimine (or sulfimide) is a type of chemical compound containing a sulfur-to-nitrogen bond which is often represented as a double bond (). In fact, a double bond violates the octet rule, and the bond may be considered a single ...
s.
At the
University of North Carolina Evans assembled a research team of undergraduates, graduate students, and postdoctoral fellows from around the world. In the 1980s, a
Ford Foundation Fellowship
The Ford Foundation is an American private foundation with the stated goal of advancing human welfare. Created in 1936 by Edsel Ford and his father Henry Ford, it was originally funded by a US$25,000 gift from Edsel Ford. By 1947, after the death ...
allowed him to create ties between his research team and a research group at the
Paul Sabatier University in France, where he spent a full sabbatical year. Later, with the help of a
Fulbright Fellowship, he built ties with groups in Mexico, Poland, Germany, Greece, and Russia.
Evans championed recruiting minority applicants to UNC-Chapel Hill,
while on the national front, he served on committees of the
American Chemical Society, the
National Institutes of Health, the
National Science Foundation, and was chair of the U.S. National Committee of the
International Union of Pure and Applied Chemistry.
He also served on a council that advised the
National Institute of General Medical Sciences.
Selected publications
*
*
*
*
*
Awards and recognition
*1994 — Tanner Award for Teaching Excellence
*1995 — NSF Special Creativity Award in Organophosphorus Chemistry
*1998 — ACS Award for Encouraging Disadvantaged Students into Careers in the Chemical Sciences
*Chancellor's Award for Excellence in Undergraduate Education
*Howard University Outstanding Achievement Award
Personal life
Evans married Tommie Johnson in 1967. They had two children. Evans died on March 24, 2001, in
Chapel Hill Chapel Hill or Chapelhill may refer to:
Places Antarctica
*Chapel Hill (Antarctica) Australia
* Chapel Hill, Queensland, a suburb of Brisbane
* Chapel Hill, South Australia, in the Mount Barker council area
Canada
*Chapel Hill, Ottawa, a neighbo ...
. The Slayton A. Evans Jr. Memorial Lecture Fund
and the Slayton Evans Research Award were both named in his honor post-humously.
References
{{DEFAULTSORT:Evans, Slayton A
1943 births
2001 deaths
20th-century American chemists
African-American chemists
Case Western Reserve University alumni
Dartmouth College faculty
Stereochemists
Tougaloo College alumni
University of North Carolina at Chapel Hill faculty