Simplicius may refer to:
; Persons
*
Pope Simplicius
Pope Simplicius (died 2 or 10 March 483) was the bishop of Rome from 468 to his death on 10 March 483. He combated the Eutychian heresy, ended the practice of consecrating bishops only in December, and sought to offset the effects of Germanic i ...
(d. 483 AD)
*
Simplicius of Cilicia
Simplicius of Cilicia (; ; – c. 540) was a disciple of Ammonius Hermiae and Damascius, and was one of the last of the Neoplatonists. He was among the pagan philosophers persecuted by Justinian in the early 6th century, and was forced for ...
(d. c. 560 AD), philosopher
* Saint Simplicius, legendary 'founding' bishop of the Sardinian
Diocese of Civita
*
Simplicius, Constantius and Victorinus
Simplicius, Constantius and Victorinus (''Victorian(us)'') () are venerated as Christian martyrs of the 2nd century.Benedictine Monks, ''Book of the Saints'' (Kessinger Publishing, 2003), 246. Simplicius, was, according to tradition, a Christian o ...
(fl. 2nd century), Roman martyrs and saints
*
Simplicius, Faustinus and Beatrix (d. 302 or 303 AD), Roman martyrs and saints
; Art and fiction
* ''
Simplicius Simplicissimus
''Simplicius Simplicissimus'' () is a picaresque novel of the lower Baroque style, written in five books by German author Hans Jakob Christoffel von Grimmelshausen published in 1668, with the sequel ''Continuatio'' appearing in 1669. Inspired b ...
'', a picaresque novel about the character of the same name
*
''Simplicius'' (operetta), an operetta by Johann Strauss II
* A character in ''
Dialogue Concerning the Two Chief World Systems
''Dialogue Concerning the Two Chief World Systems'' (''Dialogo sopra i due massimi sistemi del mondo'') is a 1632 book by Galileo Galilei comparing Nicolaus Copernicus's Copernican heliocentrism, heliocentric system model with Ptolemy's geocen ...
'', a 1632 work by Galileo
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