Simmondsin is a component of

jojoba Jojoba (; botanical name: ''Simmondsia chinensis'')also commonly called goat nut, deer nut, pignut, wild hazel, quinine nut, coffeeberry, and gray box bushis an evergreen, dioecious shrub native to the Southwestern United States and northern M ...

seeds (pronounced "ho-HO-bah") ('' Simmondsia chinensis''). While it had been considered toxic due to jojoba seed meal causing weight loss in animals, in recent years its

appetite suppressant An anorectic is a drug that reduces appetite, resulting in lower food consumption, leading to weight loss. These substances work by affecting the central nervous system or certain neurotransmitters to create a feeling of fullness or reduce the desi ...

effect has also been researched as a potential treatment for obesity. It is thought to reduce appetite by increasing levels of

cholecystokinin Cholecystokinin (CCK or CCK-PZ; from Greek ''chole'', "bile"; ''cysto'', "sac"; ''kinin'', "move"; hence, ''move the bile-sac (gallbladder)'') is a peptide hormone of the gastrointestinal system responsible for stimulating the digestion of fat a ...

References

Anorectics Cyanogenic glycosides Plant toxins {{gastrointestinal-drug-stub