Simmondsin is a component of
jojoba
Jojoba (; botanical name: ''Simmondsia chinensis'')also commonly called goat nut, deer nut, pignut, wild hazel, quinine nut, coffeeberry, and gray box bushis an evergreen, dioecious shrub native to the Southwestern United States and northern M ...
seeds (pronounced "ho-HO-bah") (''
Simmondsia chinensis''). While it had been considered toxic due to jojoba seed meal causing weight loss in animals, in recent years its
appetite suppressant
An anorectic is a drug that reduces appetite, resulting in lower food consumption, leading to weight loss. These substances work by affecting the central nervous system or certain neurotransmitters to create a feeling of fullness or reduce the desi ...
effect has also been researched as a potential treatment for obesity. It is thought to reduce appetite by increasing levels of
cholecystokinin
Cholecystokinin (CCK or CCK-PZ; from Greek ''chole'', "bile"; ''cysto'', "sac"; ''kinin'', "move"; hence, ''move the bile-sac (gallbladder)'') is a peptide hormone of the gastrointestinal system responsible for stimulating the digestion of fat a ...
.
References
Anorectics
Cyanogenic glycosides
Plant toxins
{{gastrointestinal-drug-stub