Silvestro is both a surname and a masculine Italian given name. Notable people with the name include:
Surname:
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Alex Silvestro (born 1988), American football player
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Chris Silvestro (born 1979), Scottish footballer
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Jim Silvestro (born 1963), Australian rules footballer
* Milo Silvestro, Italian musician, and lead singer of American heavy metal band
Fear Factory
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René De Silvestro (born 1996), Italian para alpine skier
Given name:
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Silvestro Aldobrandini (1500–1558), Italian lawyer
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Silvestro de Buoni (died 1484), Italian Renaissance painter
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Silvestro Chiesa (died 1657), Italian Baroque painter
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Silvestro Durante (died 1672), Italian Baroque composer
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Silvestro Ganassi dal Fontego (born 1492), Italian musician
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Silvestro de' Gigli (died 1521), Italian Roman Catholic bishop
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Silvestro Lega (1826–1895), Italian painter
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Sylvestro "Pedro" Morales (18??–1???), Mexican bandit
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Silvestro Palma (1754–1834), Italian composer
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Silvestro Valiero (1630–1700), Doge of Venice
{{given name, type=both
Italian masculine given names