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Sialography (also termed radiosialography) is the radiographic examination of the
salivary gland The salivary glands in many vertebrates including mammals are exocrine glands that produce saliva through a system of ducts. Humans have three paired major salivary glands ( parotid, submandibular, and sublingual), as well as hundreds of min ...
s. It usually involves the injection of a small amount of contrast medium into the salivary duct of a single gland, followed by routine
X-ray An X-ray (also known in many languages as Röntgen radiation) is a form of high-energy electromagnetic radiation with a wavelength shorter than those of ultraviolet rays and longer than those of gamma rays. Roughly, X-rays have a wavelength ran ...
projections. The resulting image is called a sialogram. Sialography has largely been replaced by sialoendoscopy and cross-sectional imaging, such as CT,
MRI Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to generate pictures of the anatomy and the physiological processes inside the body. MRI scanners use strong magnetic fields, magnetic field gradients, and rad ...
and ultrasonography.


Uses

This procedure is indicated when there is recurrent swelling and pain on the face but ultrasound has not revealed any problems. If Sjögren syndrome (also known as Sicca syndrome, an autoimmune disease that affects the lacrimal and salivary glands, causing reduced tears and saliva production) is suspected, this procedure is useful. Besides, when interventional proecudre is planned such as stone removal from salivary ducts or dilatation of the strictures in the salivary gland, this procedure is also indicated. However, for those who are pregnant, with allergy to iodinated contrast, and ongoing infection or inflammation of the face, the procedure is contraindicated.


Procedure

Contrast agents are classified into two groups: fat-soluble contrast agents and water-soluble contrast agents. Water-soluble contrast agents can fill the finer elements of the ductal system. Fat-soluble contrast agents are viscous and can cause allergic reactions. These can also cause discomfort to the patients. Fat-soluble contrast agents do not fill finer elements of the duct. A baseline radiograph (scout film) of the required salivary gland would be taken, the duct is dilated using graded lacrimal probes, a
cannula A cannula (; Latin meaning 'little reed'; : cannulae or cannulas) is a tube that can be inserted into the body, often for the delivery or removal of fluid or for the gathering of samples. In simple terms, a cannula can surround the inner or out ...
then is inserted in this salivary gland duct's opening in the mouth, then a radio-opaque fluid (contrast medium) is injected in the duct through a small tube. A series of radiographs would then be taken to determine the flow of the fluid, identify any obstructions and its location, the rate of fluid excretion from the gland. Usually the radiographs taken are lateral oblique views of the face as orthopantomograms are not useful for the purpose of locating the area due to superimpositions and the way they are taken to put the teeth in the main field.


Interpretation

This study is interpreted by evaluating the morphology of the salivary ducts for obstructions and chronic inflammation. Sialodochitis is a term describing dilation of the ducts caused by repeated inflammatory or infective processes. There is also irregular salivary duct stricture (narrowing) of the duct, which creates an appearance known as "sausage link" pattern on a sialogram. Suggestions of abscesses and autoimmune diseases such as Sjögren syndrome can also be elicited. Sialadenitis is inflammation of the salivary glands, which may cause acinar
atrophy Atrophy is the partial or complete wasting away of a part of the body. Causes of atrophy include mutations (which can destroy the gene to build up the organ), malnutrition, poor nourishment, poor circulatory system, circulation, loss of hormone, ...
and create an appearance known as "pruning of the tree" on a sialogram, where there are less branches visible from the duct system. A space occupying lesion that occurs within or adjacent to a salivary gland can displace the normal anatomy of the gland. This may create an appearance known as "ball in hand" on an sialogram, where the ducts are curved around the mass of the lesion.


Adverse effects

Like any medical imaging utilizing
ionizing radiation Ionizing (ionising) radiation, including Radioactive decay, nuclear radiation, consists of subatomic particles or electromagnetic waves that have enough energy per individual photon or particle to ionization, ionize atoms or molecules by detaching ...
, there will be a degree of direct ionizing damage and indirect damage from
free radical A daughter category of ''Ageing'', this category deals only with the biological aspects of ageing. Ageing Biogerontology Biological processes Causes of death Cellular processes Gerontology Life extension Metabolic disorders Metabolism ...
s created during the ionization of water molecules within cells. The risk of causing the development of a malignant tumor is incredibly small, and is weighed against the benefits of the investigation on a case-by-case basis. Possible complications include: * Pain on injection, * Post procedural infection, * Ductal rupture, * Extravasation of contrast media, * Allergic reaction to iodinated contrast media (which may present with urticaria, dyspnoea, and
hypotension Hypotension, also known as low blood pressure, is a cardiovascular condition characterized by abnormally reduced blood pressure. Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood and is ...
).


References

{{Medical imaging Projectional radiography Digestive system imaging