A sialoglycoprotein is a combination of sialic acid and

glycoprotein Glycoproteins are proteins which contain oligosaccharide chains covalently attached to amino acid side-chains. The carbohydrate is attached to the protein in a cotranslational or posttranslational modification. This process is known as g ...

, which is, itself, a combination of sugar and

protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respon ...

. These proteins often contain one or more sialyl oligosaccharides that are covalently bound to the rest of the molecule. Glycophorin C is one common sialoglycoprotein.

Podocalyxin Podocalyxin, a sialoglycoprotein, is thought to be the major constituent of the glycocalyx of podocytes in the glomerulus ( Bowman's capsule) in the kidneys. It is a member of the CD34 family of transmembrane sialomucins. It coats the secondar ...

is another sialoglycoprotein found in the foot processes of the podocyte cells of the glomerulus in kidneys.

is negatively charged and therefore repels other negatively charged molecules, thus contributing to the minimal filtration of negatively charged molecules by the kidney. Its molecular weight is 46 kDa.

References

External links

* Glycoproteins {{Protein-stub