HOME

TheInfoList



OR:

{{Infobox company , name = Resonac K.K. , native_name = レゾナック株式会社 , native_name_lang = ja , romanized_name = Rezonakku kabushiki gaisha , logo = Resonac logo.svg , type =
Public In public relations and communication science, publics are groups of individual people, and the public (a.k.a. the general public) is the totality of such groupings. This is a different concept to the sociology, sociological concept of the ''Öf ...
, traded_as = {{tyo, 4004 , hq_location_city =
Tokyo Tokyo, officially the Tokyo Metropolis, is the capital of Japan, capital and List of cities in Japan, most populous city in Japan. With a population of over 14 million in the city proper in 2023, it is List of largest cities, one of the most ...
, hq_location_country = Japan , key_people = Mitsuo Ohashi (chairman)
Hideo Ichikawa (president & CEO) , industry =
Chemicals A chemical substance is a unique form of matter with constant chemical composition and characteristic properties. Chemical substances may take the form of a single element or chemical compounds. If two or more chemical substances can be combin ...
, products = {{unbulleted list,
Inorganic An inorganic compound is typically a chemical compound that lacks carbon–hydrogen bonds⁠that is, a compound that is not an organic compound. The study of inorganic compounds is a subfield of chemistry known as '' inorganic chemistry''. Inor ...
s,
Aluminium Aluminium (or aluminum in North American English) is a chemical element; it has chemical symbol, symbol Al and atomic number 13. It has a density lower than that of other common metals, about one-third that of steel. Aluminium has ...
,
Electronics Electronics is a scientific and engineering discipline that studies and applies the principles of physics to design, create, and operate devices that manipulate electrons and other Electric charge, electrically charged particles. It is a subfield ...
,
Chemicals A chemical substance is a unique form of matter with constant chemical composition and characteristic properties. Chemical substances may take the form of a single element or chemical compounds. If two or more chemical substances can be combin ...
, operating_income = JPY 76.7 billion (2007) , net_income = JPY 1,023.2 billion (2007) , num_employees = 15,778 (2008) , homepage = {{URL, resonac.com} {{Nihongo, Resonac, レゾナック株式会社, Rezonakku Kabushiki-gaisha}, formerly {{Nihongo, Showa Denko K. K., 昭和電工株式会社, Shōwa Denkō Kabushiki-gaisha, abbreviated as SDK, is a Japanese chemical company producing chemical products and industrial materials. It was founded in 1939 by the merger of Nihon Electrical Industries and Showa Fertilizers, both established by a
Japan Japan is an island country in East Asia. Located in the Pacific Ocean off the northeast coast of the Asia, Asian mainland, it is bordered on the west by the Sea of Japan and extends from the Sea of Okhotsk in the north to the East China Sea ...
ese entrepreneur Nobuteru Mori. Resonac's products serve a wide array of fields ranging from
heavy industry Heavy industry is an industry that involves one or more characteristics such as large and heavy products; large and heavy equipment and facilities (such as heavy equipment, large machine tools, huge buildings and large-scale infrastructure); o ...
to the electronic and computer industries. The company is divided in five business sectors: petrochemicals (
olefins In organic chemistry, an alkene, or olefin, is a hydrocarbon containing a carbon–carbon double bond. The double bond may be internal or at the terminal position. Terminal alkenes are also known as α-olefins. The International Union of P ...
, organic chemicals, plastic products),
aluminum Aluminium (or aluminum in North American English) is a chemical element; it has chemical symbol, symbol Al and atomic number 13. It has a density lower than that of other common metals, about one-third that of steel. Aluminium has ...
(aluminum cans, sheets, ingots, foils), electronics (
semiconductors A semiconductor is a material with electrical conductivity between that of a conductor and an insulator. Its conductivity can be modified by adding impurities (" doping") to its crystal structure. When two regions with different doping levels ...
, ceramic materials,
hard disk drive A hard disk drive (HDD), hard disk, hard drive, or fixed disk is an electro-mechanical data storage device that stores and retrieves digital data using magnetic storage with one or more rigid rapidly rotating hard disk drive platter, pla ...
platters), chemicals (
industrial gases Industrial gases are the gaseous materials that are manufactured for use in industry. The principal gases provided are nitrogen, oxygen, carbon dioxide, argon, hydrogen, helium and acetylene, although many other gases and mixtures are also av ...
,
ammonia Ammonia is an inorganic chemical compound of nitrogen and hydrogen with the chemical formula, formula . A Binary compounds of hydrogen, stable binary hydride and the simplest pnictogen hydride, ammonia is a colourless gas with a distinctive pu ...
,
agrochemicals An agrochemical or agrichemical, a contraction of ''agricultural chemical'', is a chemical product used in industrial agriculture. Agrichemical typically refers to biocides (pesticides including insecticides, herbicides, fungicides and nematicid ...
), and inorganic materials (ceramics,
graphite Graphite () is a Crystallinity, crystalline allotrope (form) of the element carbon. It consists of many stacked Layered materials, layers of graphene, typically in excess of hundreds of layers. Graphite occurs naturally and is the most stable ...
electrodes). Showa Denko has more than 180 subsidiaries and affiliates. The company has vast overseas operations and a joint venture with
Netherlands , Terminology of the Low Countries, informally Holland, is a country in Northwestern Europe, with Caribbean Netherlands, overseas territories in the Caribbean. It is the largest of the four constituent countries of the Kingdom of the Nether ...
-based Montell and Nippon Petrochemicals to make and market
polypropylene Polypropylene (PP), also known as polypropene, is a thermoplastic polymer used in a wide variety of applications. It is produced via chain-growth polymerization from the monomer Propene, propylene. Polypropylene belongs to the group of polyolefin ...
s. In March 2001, Resonac merged with Showa Denko Aluminum Corporation to strengthen the high-
value-added Value added is a term in economics for calculating the difference between market value of a product or service, and the sum value of its constituents. It is relatively expressed by the demand curve, supply-demand curve for specific units of sale. ...
fabricated aluminum products operations, and is today developing next-generation optical communications-use wafers. Showa Denko is a member of the Mizuho
keiretsu A is a set of companies with interlocking business relationships and shareholdings that dominated the Japanese economy in the second half of the 20th century. In the legal sense, it is a type of business group that is in a loosely organized al ...
.


History

* Dec 1908 : Sobo Marine Products K.K. was established by Showa Denko (SDK) founder, Nobuteru Mori, to manufacture and sell
iodine Iodine is a chemical element; it has symbol I and atomic number 53. The heaviest of the stable halogens, it exists at standard conditions as a semi-lustrous, non-metallic solid that melts to form a deep violet liquid at , and boils to a vi ...
in
Chiba Prefecture is a Prefectures of Japan, prefecture of Japan located in the Kantō region of Honshu. Chiba Prefecture has a population of 6,278,060 (1 June 2019) and has a geographic area of . Chiba Prefecture borders Ibaraki Prefecture to the north, Saitama ...
. Sobo Marine Products subsequently developed into Nihon Iodine K.K. * Oct 1926 : Nihon Iodine K.K. was established. * Apr 1928 : {{nihongo, Showa Fertilizer K.K., 昭和肥料, Shōwa Hiryō was established, also by Nobuteru Mori. * Apr 1931 : Showa Fertilizers opened the first
ammonium sulfate Ammonium sulfate (American English and international scientific usage; ammonium sulphate in British English); (NH4)2SO4, is an inorganic salt with a number of commercial uses. The most common use is as a soil fertilizer. It contains 21% nitrogen a ...
factory in Japan. * Mar 1934 : Nihon Iodine K.K. was renamed as Nihon Electrical Industries K.K. * Jun 1939 : Nihon Electrical Industries and Showa Fertilizers merged to form Showa Denko K.K. * May 1949 : SDK was listed on
Tokyo Stock Exchange The , abbreviated as Tosho () or TSE/TYO, is a stock exchange located in Tokyo, Japan. The exchange is owned by Japan Exchange Group (JPX), a holding company that it also lists (), and operated by Tokyo Stock Exchange, Inc., a wholly owned sub ...
. * Sept 1951 : SDK was awarded the first
Deming Prize The Deming Prize is the longest-running national quality award and one of the highest awards in the world. It recognizes both individuals for their contributions to the field of quality and businesses that have successfully implemented exemplary s ...
. * 1968 : Dumped mercury in the Agano River, which caused widespread
mercury poisoning Mercury poisoning is a type of metal poisoning due to exposure to mercury. Symptoms depend upon the type, dose, method, and duration of exposure. They may include muscle weakness, poor coordination, numbness in the hands and feet, skin rashe ...
* Apr 1969 : Oita Petrochemical Complex started commercial operation. * Mar 1977 : Second expansion project of
ethylene Ethylene (IUPAC name: ethene) is a hydrocarbon which has the formula or . It is a colourless, flammable gas with a faint "sweet and musky" odour when pure. It is the simplest alkene (a hydrocarbon with carbon–carbon bond, carbon–carbon doub ...
production capacity was completed at SDK Oita Petrochemical Complex. * Feb 1986 : SDK withdrew from its domestic aluminum smelting business. * Nov 1989 : Hard Disk Plant No 1 completed in Chiba. * Jan 1995 : Omachi Works obtained
ISO 9001 The ISO 9000 family is a set of international standards for quality management systems. It was developed in March 1987 by International Organization for Standardization. The goal of these standards is to help organizations ensure that they meet ...
certification. * May 1997 : Production Technology Center obtained
ISO 14001 The ISO 14000 family is a set of international standards for Natural environment, environment management systems. It was developed in March 1996 by International Organization for Standardization. The goal of these standards is to help organizations ...
certification. * Mar.2001 : SDK merged with Showa Aluminum Corporation. * Sept.2003 : Japan Polyolefins Co., Ltd. and Japan Polychem Corporation integrated the polyethylene businesses and established a new
joint venture A joint venture (JV) is a business entity created by two or more parties, generally characterized by shared ownership, shared returns and risks, and shared governance. Companies typically pursue joint ventures for one of four reasons: to acce ...
company. * Jul.2004 : Trace Strage Technology Corp., become a consolidated subsidiary. * Nov.2004 : SDK announced to produce high-power blue
LED A light-emitting diode (LED) is a semiconductor device that emits light when current flows through it. Electrons in the semiconductor recombine with electron holes, releasing energy in the form of photons. The color of the light (corresp ...
chips. * Mar 2005 : SDK sold shares in SDS Biotech K.K. via
management buyout A management buyout (MBO) is a form of acquisition in which a company's existing managers acquire a large part, or all, of the company, whether from a parent company or individual. Management- and/or leveraged buyouts became noted phenomena of 19 ...
scheme. * Jul 2005 : SDK started production of world's first perpendicular magnetic recording technology HD media. * Jan 2006 : SDK opened new medium-term consolidated business plan "PASSION Project" for the 2006-2008 period. * Sept 2006 : SDK opened new aluminum cylinders plant in Oita. * Dec 2006 : SDK opened new hard disk media plant in
Singapore Singapore, officially the Republic of Singapore, is an island country and city-state in Southeast Asia. The country's territory comprises one main island, 63 satellite islands and islets, and one outlying islet. It is about one degree ...
. * Feb 2007 : SDK develops new crystal growth technology for
GaN The word Gan or the initials GAN may refer to: Places * Gan, a component of Hebrew placenames literally meaning "garden" China * Gan River (Jiangxi) * Gan River (Inner Mongolia), * Gan County, in Jiangxi province * Gansu, abbreviated '' ...
-based blue/white LEDs. * Sept 2007 : SDK opened its second
neodymium Neodymium is a chemical element; it has Symbol (chemistry), symbol Nd and atomic number 60. It is the fourth member of the lanthanide series and is considered to be one of the rare-earth element, rare-earth metals. It is a hard (physics), hard, sli ...
-based alloys plant in
China China, officially the People's Republic of China (PRC), is a country in East Asia. With population of China, a population exceeding 1.4 billion, it is the list of countries by population (United Nations), second-most populous country after ...
. * Jun 2008 : Showa Tansan Co., Ltd. become a consolidated subsidiary. * Dec 2019 : SDK acquired Hitachi Chemical for US$8.8 billion to scale up the
lithium-ion battery A lithium-ion or Li-ion battery is a type of rechargeable battery that uses the reversible intercalation of Li+ ions into electronically conducting solids to store energy. Li-ion batteries are characterized by higher specific energy, energ ...
and advanced materials businesses. * June 2020 : Hitachi Chemical was renamed as Showa Denko Materials. * Jan 2023 : Showa Denko K.K. and Showa Denko Materials Co., Ltd. merge to form Resonac.{{Cite web , title=Showa Denko reborn as Resonac , url=https://www.resonac.com/corporate/name-change.html , access-date=2023-03-23 , website=www.resonac.com


Group companies

Hard Disc Media * Showa Denko HD Pte., Ltd. Petrochemicals * Showa Highpolymer Co., Ltd. Chemicals * GMM Nonstick Coatings * Nippon Polytech Corp. Inorganics * Showa Titanium Co., Ltd. * Showa Denko Kenso Co., Ltd. * Tohoku Metal Chemical Co., Ltd. Aluminum * Showa Aluminum Can Corp. * Showa Denko Aluminum Trading K.K. * Showa Denko Packaging Co., Ltd. Electronics, other * Showa Engineering Co., Ltd. * Showa Denko Kenzai K.K. * Shoko Co., Ltd. * Fuyo Perlite Co., Ltd. * Union Showa K.K.


Petrochemicals sector

The Petrochemicals Sector supports the growth of Showa Denko's basic business through the manufacture and sales of organic chemicals, olefins and specialty polymers. SDK is the leader of the Asian
ethyl acetate Ethyl acetate commonly abbreviated EtOAc, ETAC or EA) is the organic compound with the formula , simplified to . This flammable, colorless liquid has a characteristic sweet smell (similar to pear drops) and is used in glues, nail polish removers, ...
market. The Oita Plant, the main manufacturing base, supplies SDK and other chemical companies with the basic materials for making acetyl derivatives, synthetic resin,
synthetic rubber A synthetic rubber is an artificial elastomer. They are polymers synthesized from petroleum byproducts. About of rubber is produced annually in the United States, and of that amount two thirds are synthetic. Synthetic rubber, just like natural ru ...
, and styrene monomers. Innovative products include a new heat-resistant, transparent sheet and film that can be used in flexible displays such as electronic paper and organic EL displays.


Chemicals sector

Originally focused on general-purpose industrial gases, medical gases, and industrial chemicals, SDK now provides a variety of products including high-purity gases and chemicals for the semiconductor industry. As the semiconductor industry shifted to other Asian locations, SDK established overseas specialty gases production sites in
Shanghai Shanghai, Shanghainese: , Standard Chinese pronunciation: is a direct-administered municipality and the most populous urban area in China. The city is located on the Chinese shoreline on the southern estuary of the Yangtze River, with the ...
and Singapore. The company also offers an array of technologies and products covering various fields, including food additives, feed additives, cosmetic ingredients, medical and agricultural intermediates, optical-function materials, information-recording materials, functional polymeric materials, differentiated composite material, and liquid chromatography equipment ( Shodex). SDK recently launched an environmental initiative to reduce waste and encourage chemical recycling. In 2016 Showa Denko acquired GMM Nonstick Coatings, one of the world's largest nonstick coatings companies founded in 2007 by
Ravin Gandhi Ravin Gandhi is an American businessman. Gandhi was an executive with Coatings and Chemicals Corporation before its sale to Akzo Nobel. He later founded Glenborn Partners, a private equity firm, and GMM Nonstick Coatings, where he remained its CE ...
. Clients included companies in the American housewares industry including
KitchenAid KitchenAid is an American home appliance brand owned by Whirlpool Corporation. The company was started in 1919 by The Hobart Manufacturing Company to produce Mixer (appliance), stand mixers; the H-5 is the first model that was introduced. The com ...
and Calphalon, in addition to foreign markets.


Electronics sector

The Electronics Sector includes compound semiconductors,
rare-earth magnet A rare-earth magnet is a strong permanent magnet made from alloys of rare-earth elements. Developed in the 1970s and 1980s, rare-earth magnets are the strongest type of permanent magnets made, producing significantly stronger magnetic fields tha ...
ic alloys, solid aluminum capacitors, and hard disks. The compound semiconductors business deals with the crystal growth process, providing a wide range of products including Ultrabright LED Chips as well as blue LED Chips. The solid aluminum capacitor business relies on conductive polymers, a combination of inorganic aluminum materials with organic polymers. The products offer with high heat resistance and high capacitance. The electronics sector also produces aluminum-based and glass-based hard disks as well as aluminum substrates for hard disks. In September 2008 SDK announced a consolidation their hard disk (HD) media operations by establishing a joint venture with Hoya corporation in January 2009. The joint venture was to be owned about 75% by SDK and about 25% by HOYA. However, this joint venture ended in March 2009 due to the rapid deterioration of the global economy in the Hard Disk Sector.


Inorganics sector

The Inorganics Sector consists of the Ceramics Division, Carbons Division and Fine Carbon Department. *Ceramics Division SDK's Ceramics products are used in a wide range of fields, including chemical products, refractory products, ceramics, paper manufacture, plastics and electronics. Key products include alumina hydroxide,
alumina Aluminium oxide (or aluminium(III) oxide) is a chemical compound of aluminium and oxygen with the chemical formula . It is the most commonly occurring of several aluminium oxides, and specifically identified as aluminium oxide. It is commonly ...
, and high-purity alumina. SDK also produces fused alumina abrasive grains,
silicon carbide Silicon carbide (SiC), also known as carborundum (), is a hard chemical compound containing silicon and carbon. A wide bandgap semiconductor, it occurs in nature as the extremely rare mineral moissanite, but has been mass-produced as a powder a ...
and
boron nitride Boron nitride is a thermally and chemically resistant refractory compound of boron and nitrogen with the chemical formula B N. It exists in various crystalline forms that are isoelectronic to a similarly structured carbon lattice. The hexago ...
. *Carbons Division SDK produces artificial graphite electrodes, an indispensable material for the recycling of steel. Other products include fine carburizing agents for iron casting. *Fine Carbon Department In addition to VGCF carbon nanofibers and fuel battery materials already on the market, SDK is focusing R&D efforts on high-functionality carbon products, including battery materials, electronics materials, and materials for alternative energy solutions.{{buzzword inline, date=September 2019


Aluminium sector

SDK produces heat exchangers, beverage cans, and other high value-added fabricated products from aluminum materials (including rolled, extruded and forged products).


Controversy


Niigata Minamata disease

{{Further, Niigata Minamata disease The company is known for causing the second outbreak of
Minamata disease is a neurological disease caused by severe mercury poisoning. Signs and symptoms include ataxia, numbness in the hands and feet, general muscle weakness, loss of peripheral vision, and damage to hearing and speech. In extreme cases, insanity, ...
(a type of severe
mercury poisoning Mercury poisoning is a type of metal poisoning due to exposure to mercury. Symptoms depend upon the type, dose, method, and duration of exposure. They may include muscle weakness, poor coordination, numbness in the hands and feet, skin rashe ...
) in Kanose, currently part of Aga-machi,
Niigata Prefecture is a Prefectures of Japan, prefecture in the Chūbu region of Honshu of Japan. Niigata Prefecture has a population of 2,131,009 (1 July 2023) and is the List of Japanese prefectures by area, fifth-largest prefecture of Japan by geographic area ...
, through the release of organomercury compounds into the Agano River.


Tryptophan contamination

In the 1980s Showa Denko applied
genetic engineering Genetic engineering, also called genetic modification or genetic manipulation, is the modification and manipulation of an organism's genes using technology. It is a set of Genetic engineering techniques, technologies used to change the genet ...
to the bacteria it used in the
fermentation Fermentation is a type of anaerobic metabolism which harnesses the redox potential of the reactants to make adenosine triphosphate (ATP) and organic end products. Organic molecules, such as glucose or other sugars, are catabolized and reduce ...
through which it manufactured
tryptophan Tryptophan (symbol Trp or W) is an α-amino acid that is used in the biosynthesis of proteins. Tryptophan contains an α-amino group, an α-carboxylic acid group, and a side chain indole, making it a polar molecule with a non-polar aromat ...
so that the bacteria would be more efficient. At the same time, they also changed the technique used to purify the tryptophan.Edward A Belongia, MD. Toxic Tryptophan? Investigating the Eosinophila Myalgia Syndrome in Minnesota. Chapter 26 i
Cases in Field Epidemiology: A Global Perspective
Ed Mark Dworkin. Jones & Bartlett Learning, 2011
{{rp, 327–328 Multiple epidemiological studies{{cite journal , vauthors=Slutsker L, Hoesly FC, Miller L, Williams LP, Watson JC, Fleming DW , title = Eosinophilia-myalgia syndrome associated with exposure to tryptophan from a single manufacturer , journal = JAMA , volume = 264 , issue = 2 , pages = 213–7 , year = 1990 , pmid = 2355442, doi = 10.1001/jama.264.2.213 {{cite journal , vauthors=Back EE, Henning KJ, Kallenbach LR, Brix KA, Gunn RA, Melius JM , title = Risk factors for developing eosinophilia myalgia syndrome among L-tryptophan users in New York , journal = J. Rheumatol. , volume = 20 , issue = 4 , pages = 666–72 , year = 1993 , pmid = 8496862 {{cite journal , vauthors=Kilbourne EM, Philen RM, Kamb ML, Falk H , title = Tryptophan produced by Showa Denko and epidemic eosinophilia-myalgia syndrome , journal = The Journal of Rheumatology. Supplement , volume = 46 , pages = 81–8; discussion 89–91 , year = 1996 , pmid = 8895184 traced an outbreak of eosinophilia-myalgia syndrome (EMS) to L-tryptophan supplied by Showa Denko, which resulted in 37 deaths.U. S. Food and Drug Administration Center for Food Safety and Applied Nutrition, Office of Nutritional Products, Labeling, and Dietary Supplements. February 200
FDA Information Paper on L-tryptophan and 5-hydroxy-L-tryptophan
/ref> It was further hypothesized that one or more trace impurities produced during the manufacture of tryptophan may have been responsible for the EMS outbreak.{{cite journal , vauthors=Mayeno AN, Lin F, Foote CS, Loegering DA, Ames MM, Hedberg CW, Gleich GJ , title = Characterization of "peak E," a novel amino acid associated with eosinophilia-myalgia syndrome , journal = Science , volume = 250 , issue = 4988 , pages = 1707–8 , year = 1990 , pmid = 2270484 , doi = 10.1126/science.2270484 , bibcode = 1990Sci...250.1707M {{cite journal , vauthors=Ito J, Hosaki Y, Torigoe Y, Sakimoto K , title = Identification of substances formed by decomposition of peak E substance in tryptophan , journal = Food Chem. Toxicol. , volume = 30 , issue = 1 , pages = 71–81 , year = 1992 , pmid = 1544609 , doi = 10.1016/0278-6915(92)90139-C The fact that the Showa Denko facility used genetically engineered bacteria to produce L-tryptophan gave rise to speculation that genetic engineering was responsible for such impurities.{{cite journal , vauthors=Mayeno AN, Gleich GJ , title = Eosinophilia-myalgia syndrome and tryptophan production: a cautionary tale , journal = Trends Biotechnol. , volume = 12 , issue = 9 , pages = 346–52 , date=September 1994 , pmid = 7765187 , doi = 10.1016/0167-7799(94)90035-3 However, the methodology used in the initial epidemiological studies has been criticized.{{cite journal , author = Shapiro S , title = Epidemiologic studies of the association of L-tryptophan with the eosinophilia-myalgia syndrome: a critique , journal = The Journal of Rheumatology. Supplement , volume = 46 , pages = 44–58; discussion 58–9 , year = 1996 , pmid = 8895181 {{cite journal , vauthors=Horwitz RI, Daniels SR , title = Bias or biology: evaluating the epidemiologic studies of L-tryptophan and the eosinophilia-myalgia syndrome , journal = The Journal of Rheumatology. Supplement , volume = 46 , pages = 60–72 , year = 1996 , pmid = 8895182 An alternative explanation for the 1989 EMS outbreak is that large doses of tryptophan produce
metabolites In biochemistry, a metabolite is an intermediate or end product of metabolism. The term is usually used for small molecules. Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on enzymes, c ...
which inhibit the normal degradation of
histamine Histamine is an organic nitrogenous compound involved in local immune responses communication, as well as regulating physiological functions in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus. Discovered in 19 ...
and excess histamine in turn has been proposed to cause EMS.{{cite journal , vauthors=Smith MJ, Garrett RH , title = A heretofore undisclosed crux of eosinophilia-myalgia syndrome: compromised histamine degradation , journal = Inflamm. Res. , volume = 54 , issue = 11 , pages = 435–50 , year = 2005 , pmid = 16307217 , doi = 10.1007/s00011-005-1380-7 , s2cid = 7785345 Once the link between EMS and Showa Denko's tryptophan had been established, chemical analyses of the tryptophan was performed by researchers at the
Mayo Clinic Mayo Clinic () is a Nonprofit organization, private American Academic health science centre, academic Medical centers in the United States, medical center focused on integrated health care, healthcare, Mayo Clinic College of Medicine and Science ...
, the U.S.
Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is respo ...
(FDA), the
Centers for Disease Control The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency under the Department of Health and Human Services (HHS), and is headquartered in Atlanta, ...
(CDC) and the Japanese National Institute of Hygienic Sciences to determine if any contaminants were associated with EMS. Showa Denko reportedly destroyed the GM bacterial stocks after the EMS cases began to emerge. In 2017, the last of the 6 contaminant associated with the 1989 EMS disease outbreak, labelled ''Peak AAA'', has been identified using high-resolution mass spectroscopy.{{cite journal, journal=Toxicology Letters, title=Structure determination of disease associated peak AAA from l-Tryptophan implicated in the eosinophilia-myalgia syndrome, year=2017, volume=282, pages=71–80, number=5, author=Klaus Klarskov & Al., doi=10.1016/j.toxlet.2017.10.012, pmid=29037509


References

{{Reflist {{Nikkei 225 {{Authority control Chemical companies based in Tokyo Defense companies of Japan Conglomerate companies based in Tokyo Fuyo Group Japanese companies established in 1939 Chemical companies established in 1939 Companies listed on the Tokyo Stock Exchange Companies in the Nikkei 225