Shi Yigong (; born May 1967) is a Chinese
biophysicist
Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study biological phenomena. Biophysics covers all scales of biological organization, from molecular to organismic and populations. B ...
who serves as founding and the current president of
Westlake University since April 2018.
He previously served as vice president of
Tsinghua University
Tsinghua University (; abbr. THU) is a national public research university in Beijing, China. The university is funded by the Ministry of Education.
The university is a member of the C9 League, Double First Class University Plan, Projec ...
from 2015 to 2018 and dean of Tsinghua University School of Life Sciences from 2009 to 2016.
Education
Shi Yigong received a
Bachelor of Science
A Bachelor of Science (BS, BSc, SB, or ScB; from the Latin ') is a bachelor's degree awarded for programs that generally last three to five years.
The first university to admit a student to the degree of Bachelor of Science was the University o ...
with majors in
biology
Biology is the scientific study of life. It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. For instance, all organisms are made up of cells that process hereditar ...
and
mathematics from Tsinghua University in 1989 and a
Doctor of Philosophy
A Doctor of Philosophy (PhD, Ph.D., or DPhil; Latin: or ') is the most common degree at the highest academic level awarded following a course of study. PhDs are awarded for programs across the whole breadth of academic fields. Because it is ...
in
molecular biophysics
Molecular biophysics is a rapidly evolving interdisciplinary area of research that combines concepts in physics, chemistry, engineering, mathematics and biology. It seeks to understand biomolecular systems and explain biological function in te ...
from
Johns Hopkins University
Johns Hopkins University (Johns Hopkins, Hopkins, or JHU) is a private research university in Baltimore, Maryland. Founded in 1876, Johns Hopkins is the oldest research university in the United States and in the western hemisphere. It consiste ...
in 1995.
During his graduate studies, he determined the
crystal structure
In crystallography, crystal structure is a description of the ordered arrangement of atoms, ions or molecules in a crystalline material. Ordered structures occur from the intrinsic nature of the constituent particles to form symmetric patterns t ...
of several critical apoptotic proteins, including
apaf-1
Apoptotic protease activating factor 1, also known as APAF1, is a human homolog of ''C. elegans'' CED-4 gene.
Function
The protein was identified in the lab of Xiaodong Wang as an activator of caspase-3 in the presense of cytochromeC and dATP ...
, DIAP1, and the BIR3 domain of
XIAP
X-linked inhibitor of apoptosis protein (XIAP), also known as inhibitor of apoptosis protein 3 (IAP3) and baculoviral IAP repeat-containing protein 4 (BIRC4), is a protein that stops apoptotic cell death. In humans, this protein (XIAP) is produc ...
.
Career
Shi Yigong was the Warner-Lambert/Parke-Davis Professor in the department of
Molecular Biology
Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and phys ...
at
Princeton University
Princeton University is a private research university in Princeton, New Jersey. Founded in 1746 in Elizabeth as the College of New Jersey, Princeton is the fourth-oldest institution of higher education in the United States and one of the n ...
. In June 2008, he was selected as a
Howard Hughes Medical Institute
The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, f ...
investigator. However, he rejected the award upon resigning his position at Princeton University in order to pursue his career at
Tsinghua University
Tsinghua University (; abbr. THU) is a national public research university in Beijing, China. The university is funded by the Ministry of Education.
The university is a member of the C9 League, Double First Class University Plan, Projec ...
, becoming the dean of the School of Life Sciences there. In 2003, he was appointed a Chair Professor of Tsinghua's Department of Biological Sciences and Biotechnology. In late 2007, He was appointed Vice Director of Tsinghua's Institute of Biomedicine and Vice Dean of Tsinghua's Department of Biological Sciences and Biotechnology before returning to China. He was appointed Dean of Tsinghua's School of Life Sciences (replacing the Department of Biological Sciences and Biotechnology) in 2009. In 2018, he became the founding and the first president of
Westlake University, a newly established private university in
Hangzhou
Hangzhou ( or , ; , , Standard Mandarin pronunciation: ), also romanized as Hangchow, is the capital and most populous city of Zhejiang, China. It is located in the northwestern part of the province, sitting at the head of Hangzhou Bay, wh ...
.
Shi
renounced his U.S. citizenship in 2011 in order to reclaim his Chinese citizenship.
Awards
* 2020, the
Tan Kah Kee Science Award
* 2017, the
Future Science Prize
The future is the time after the past and present. Its arrival is considered inevitable due to the existence of time and the laws of physics. Due to the apparent nature of reality and the unavoidability of the future, everything that currently ...
in Life Sciences.
* 2016, the
Ho Leung Ho Lee Award for Achievement in Science and Technology.
[https://ygshi.org/static/CV_YigongShi.pdf ]
* 2015, Nature Award for Mentoring in science.
* 2014, the
Gregori Aminoff Prize
The Gregori Aminoff Prize is an international prize awarded since 1979 by the Royal Swedish Academy of Sciences in the field of crystallography, rewarding "a documented, individual contribution in the field of crystallography, including areas conc ...
, from the Royal Swedish Academy of Sciences
* 2013, foreign associate of the US
National Academy of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nat ...
* 2013, foreign associate of the
European Molecular Biology Organization
The European Molecular Biology Organization (EMBO) is a professional, non-profit organization of more than 1,800 life scientists. Its goal is to promote research in life science and enable international exchange between scientists. It co-funds cour ...
* 2013, Academician
Chinese Academy of Sciences
The Chinese Academy of Sciences (CAS); ), known by Academia Sinica in English until the 1980s, is the national academy of the People's Republic of China for natural sciences. It has historical origins in the Academia Sinica during the Repub ...
, 中国科学院院士
* 2011,
Ray Wu Award from the Chinese Biological Investigators Society
* 2010
Raymond and Beverly Sackler International Prize
* Irving Sigal Young Investigator Award, from the
Protein Society
The Protein Society is an international, not-for-profit, Learned society, scholarly society with the mission to provide forums for the advancement of research into protein structure, function, design and applications.
History
It was founded in 1 ...
*
Searle Scholar Award
* Rita Allen Scholar Award
* 2000,
Wilson S. Stone Memorial Award
* 1995,
Paul Ehrlich Research Award in Basic Science
References
External links
Dr. Shi Yigong Appointed Vice Director of Tsinghua’s Institute of Biomedicine Tsinghua University News
Howard Hughes Medical Institute
The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, f ...
{{DEFAULTSORT:Shi, Yigong
1967 births
Living people
People from Zhengzhou
Biologists from Henan
Chinese biophysicists
Chinese emigrants to the United States
Educators from Henan
Foreign associates of the National Academy of Sciences
Howard Hughes Medical Investigators
Johns Hopkins University alumni
Members of the Chinese Academy of Sciences
Former United States citizens
Physicists from Henan
Princeton University faculty
Tsinghua University alumni
Academic staff of Tsinghua University
Members of the 14th Chinese People's Political Consultative Conference