Sherlock Biosciences is a

biotechnology Biotechnology is a multidisciplinary field that involves the integration of natural sciences and Engineering Science, engineering sciences in order to achieve the application of organisms and parts thereof for products and services. Specialists ...

company based in

Cambridge, Massachusetts Cambridge ( ) is a city in Middlesex County, Massachusetts, United States. It is a suburb in the Greater Boston metropolitan area, located directly across the Charles River from Boston. The city's population as of the 2020 United States census, ...

developing

diagnostic Diagnosis (: diagnoses) is the identification of the nature and cause of a certain phenomenon. Diagnosis is used in a lot of different academic discipline, disciplines, with variations in the use of logic, analytics, and experience, to determine " ...

tests using

CRISPR CRISPR (; acronym of clustered regularly interspaced short palindromic repeats) is a family of DNA sequences found in the genomes of prokaryotic organisms such as bacteria and archaea. Each sequence within an individual prokaryotic CRISPR is d ...

- Cas13. The company was founded in 2019 by

Feng Zhang Feng Zhang (; born October 22, 1981) is a Chinese-born American biochemist. Zhang currently holds the James and Patricia Poitras Professorship in Neuroscience at the McGovern Institute for Brain Research and in the Departments of Brain and Co ...

, Jim Collins, Omar Abudayyeh, and Jonathan Gootenberg of the

Broad Institute The Eli and Edythe L. Broad Institute of MIT and Harvard (IPA: , pronunciation respelling: ), often referred to as the Broad Institute, is a biomedical and genomic research center located in Cambridge, Massachusetts, United States. The institu ...

. Cas13 was discovered by Zheng and

Eugene Koonin Eugene Viktorovich Koonin (Russian: Евге́ний Ви́кторович Ку́нин; born October 26, 1956) is a Russian-American biologist and Senior Investigator at the National Center for Biotechnology Information (NCBI). He is a recognis ...

using

computational biology Computational biology refers to the use of techniques in computer science, data analysis, mathematical modeling and Computer simulation, computational simulations to understand biological systems and relationships. An intersection of computer sci ...

methods, and then further characterized by

Jennifer Doudna Jennifer Anne Doudna (; born February 19, 1964) is an American biochemist who has pioneered work in CRISPR gene editing, and made other fundamental contributions in biochemistry and genetics. She received the 2020 Nobel Prize in Chemistry, wit ...

's team at the

University of California, Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California), is a Public university, public Land-grant university, land-grant research university in Berkeley, California, United States. Founded in 1868 and named after t ...

. In 2020, both Sherlock Biosciences and

Mammoth Biosciences Mammoth Biosciences is a biotechnology company based in Brisbane, California developing diagnostic tests using CRISPR-Cas12a and CRISPR-based therapies using its proprietary ultra-small CRISPR systems. Several CRISPR-Cas systems identified throug ...

from Doudna's lab at UC Berkeley used their similar CRISPR technologies to develop tests for

COVID-19 Coronavirus disease 2019 (COVID-19) is a contagious disease caused by the coronavirus SARS-CoV-2. In January 2020, the disease spread worldwide, resulting in the COVID-19 pandemic. The symptoms of COVID‑19 can vary but often include fever ...

. In 2021, Sherlock Biosciences and The Forsyth Institute entered into a strategic partnership with its focus being on the research and development of products related to the “detection of human biomarkers in oral cavity and other oral health applications."

External links

Company webpage

References

American companies established in 2019 Biotechnology companies of the United States Genomics companies Health care companies based in Massachusetts Life sciences industry Medical diagnosis {{US-company-stub

See also

External links

References